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1 MC is mandatory for appropriate treatment to be rendered.
2 c community, so that prompt intervention may be rendered.
4 w how enhancers of macrophage-specific genes are rendered accessible in differentiating macrophages t
5 istence of labile assembly machines that can be rendered accessible as next-generation drug targets b
7 Here, we show that hydrophobic P4 molecules are rendered air-stable and water-soluble within the hyd
12 ls activated in the absence of costimulation are rendered anergic and are hyporesponsive when present
13 igens are present with low frequency and may be rendered anergic by the tumors that express them, we
16 the catalytic activity of a light chain can be rendered antigen-specific by pairing with a noncovale
17 on CD95 is frequently downregulated or cells are rendered apoptosis resistant, raising the possibilit
18 resistant to TNFalpha-induced apoptosis but are rendered apoptosis-sensitive on coculture with strom
22 te vector-based drawings and scenes that can be rendered as raster-graphics images, allowing for easy
26 e critically considered, and overall opinion is rendered based on the available peer-reviewed literat
28 ully mismatched lung grafts from donors that were rendered brain dead and mechanically ventilated for
29 Following each bump, individual microvilli are rendered briefly (~100-200 ms) refractory, thereby r
30 hat the smooth, regular, structures produced are rendered by highly dynamic supramolecular transforma
31 , respectively, whereas enzymatic inhibition was rendered by a potent second-generation small molecul
32 ly constitutes a key step in exocytosis that is rendered Ca(2+)-dependent by interactions with synapt
33 r and the boronic acid at copper; the system is rendered catalytic in copper under the aerobic condit
36 lamino)pyridine (DMAP) and benzoic anhydride are rendered chiral via interaction with a chiral thiour
38 acoresistant temporal lobe epilepsy will not be rendered completely seizure-free after temporal lobe
40 s of in vitro aggregation of alpha-synuclein are rendered complex because of the formation of a heter
41 ty, B6 mice bearing the human CD19 transgene were rendered congenic for the Sle1(z) genetic locus and
43 kinase is an important cellular enzyme that is rendered constitutively active in the breakpoint clus
44 required for LRT persistence even when BvgAS is rendered constitutively active, suggesting the presen
45 synapse from mutant mice in which syntaxin-1 is rendered constitutively open and SNARE-complex assemb
46 s cause similar phenotypic defects when they are rendered defective by mutation, but the underlying c
49 fide-bonded Agp is not dependent on DsbC but is rendered dependent by engineering into it the conserv
50 r-driven NF-kappaB activity (CARMA1-KO mice) were rendered diabetic and transplanted with islet allog
56 AND Cav1 knockout and wild-type C57BL/6 mice were rendered diabetic with streptozotocin, and changes
59 e expression of a glutamate-terminal protein is rendered difficult because the N-terminal methionine
61 d relapse or achieved an incomplete response were rendered disease free by salvage surgical resection
62 as been broadly implicated in longevity, but is rendered dispensable for rIIS lifespan extension by e
63 findings suggest that the basement membrane is rendered distensible by proteolytic degradation to al
65 the discovery of key cellular pathways that are rendered dysfunctional during cancer progression.
67 ct DNA repair pathways depending on how they are rendered dysfunctional, and that A-NHEJ is a major p
68 fection, plasmacytoid dendritic cells (pDCs) are rendered dysfunctional, as measured by their decreas
70 stant to extinction, but extinction training was rendered effective when the training was combined wi
72 carbinols and nitroalkene substrates and can be rendered enantioselective and diastereoselective by t
73 st that many processes that rely on SmI2 can be rendered enantioselective by the design of suitable l
74 of appropriate chiral ligands, this reaction is rendered enantioselective and applies to both aromati
75 WT) control, TxNIP(-/-), and TxNIP(+/-) mice were rendered equally diabetic with low-dose streptozoto
76 ddress this question, we have used mice that were rendered estradiol-deficient or estradiol-resistant
77 sensitivity to IL-7 and IL-15, whereby they are rendered "fit" for homeostatic self-renewal as well
79 netic field enhancement of charge order that is rendered fragile in zero magnetic fields because of i
82 llular rejection at the time of testing that is rendered from a single ordinal gene-expression profil
83 llular rejection at the time of testing that is rendered from a single ordinal gene-expression profil
86 accessibility when PDZ2 is occupied, and can be rendered functional in vivo by additional mutation of
87 that the process of CD8(+) T cell activation is rendered fundamentally different by early life AHR si
92 t the genome except at the test locus, which is rendered hemizygous for alternative alleles from the
93 PdCl(2) catalysts without requiring them to be rendered heterogeneous, the addition of exogenous lig
95 inistic control of ferroelastic domains that are rendered highly mobile in a controlled and reversibl
96 ia a simple two-step synthesis, the pigments are rendered highly soluble in organic solvents and in p
99 ramics, which are generally hydrophilic, can be rendered hydrophobic by polymeric modifiers, these de
100 erties of CB[7], the inner cavity of MOP can be rendered hydrophobic by using octadecyl HDA (3) as gu
101 c" system between two mica surfaces that had been rendered hydrophobic by the adsorption of a double-
103 oxO1 (L-FoxO1) and their control littermates were rendered hyperglycemic by streptozotocin administra
105 bryonic Ag expressed by a variety of tumors, is rendered immunogenic if targeted to the APCs using th
108 ostate biopsies stained with acridine orange are rendered in seconds and contain excellent contrast a
109 is normally in a nucleosome-depleted region, is rendered inaccessible by altered nucleosome positioni
110 no experimental information is included but were rendered inaccurate by the SHAPE data of Das and co
115 eveloping new plasmids in which the pBt gene is rendered inactive after excision of the transposon fr
117 unable to achieve the fully closed state and is rendered inactive despite possessing all of the resid
120 ing in a subset of CRPC tumors as the AR-LBD is rendered inactive, suggesting an important mechanism
123 vely acid-stable hemagglutinin (HA) proteins are rendered incapable of pH-induced triggering for memb
124 proton channel, the mechanisms by which they are rendered ineffective against M2S31N are unclear.
125 examples in which small molecule inhibitors are rendered ineffective when their kinase targets are i
127 circumvent known resistance mechanisms, can be rendered ineffective by unrecognised adaptations in t
131 paired by sediment infilling, croplands will be rendered infertile by salt, and water scarcity will p
132 lt and 5 prepubertal recipient macaques that were rendered infertile with alkylating chemotherapy.
134 Viruses inhibited by pseudoknot aptamers were rendered insensitive by a naturally occurring R277K
135 H)(2)D(3) in control cells, almost all (113) were rendered insensitive to the hormone in VDRE-BP-over
136 od effects were included, cohort differences were rendered insignificant (OR = 1.23, 95% CI: 0.78, 1.
140 use xenograft models of human glioma and can be rendered into three-dimensional images offering exqui
141 ns of maturing animals of several species to be rendered into vellum of equal quality and fineness.
142 on binding to fibrillin-1, the BMP-7 complex is rendered into a closed ring shape, which also confers
143 t existing genome browsers, where the genome is rendered into images on the webserver and the role of
145 isual synchrony even when the visual stimuli are rendered invisible through interocular masking.
146 ssion, a suprathreshold monocular target can be rendered invisible by a salient competitor stimulus p
148 A testing stimulus presented to one eye was rendered invisible by a masking stimulus presented t
150 versions in which the hierarchical structure was rendered irregular whereas the local structure was k
151 r, the VAT-Claisen reaction described herein is rendered irreversible by C-C bond cleavage, not by de
152 ed to retinal ischemia after IPC, or retinas were rendered ischemic after pharmacological opening of
157 l medicines discovered in a cellular screen, are rendered less active by mutations in a parasite P-ty
160 ch as artemisinin combination therapies have been rendered less effective due to developing parasite
161 ls; toddlers failed when these trials either were rendered less effective or were used in a high-inhi
162 ped with dideoxy termini, whereas 3'-PG ends were rendered ligatable, linked to an anchor, and quanti
163 ongly enhanced when the mRNA decay machinery is rendered limiting by mRNA decay enzyme depletion or T
164 ue clearing in which whole organs and bodies are rendered macromolecule-permeable and optically trans
166 rs are crystallographically inequivalent but are rendered magnetically equivalent on the time scale o
167 osome missegregation rates have been reduced are rendered markedly more resistant to IR, exhibiting d
168 found that membrane-permeable bioagents can be rendered membrane impermeable by covalent attachment
169 east cancer cells with the inhibitors, which were rendered membrane permeable by attachment of an oct
171 bed only during growth on methanol, mcrBDCGA was rendered methanol dependent and the strain was unabl
175 cate that several transient Env epitopes can be rendered more accessible to antibodies (Abs) via spec
176 as "carbohydrate-like" behaviour may need to be rendered more flexible, at least as far as interactio
178 is either native to both continents but has been rendered more pathogenic in North America by mutati
179 ency to allow genome-wide investigation, but is rendered more flexible by sampling regression coeffic
181 upon restoration of extracellular Ca(2+) but were rendered more sustained by the PLC inhibitors.
183 with high molecular weight DNA, SNM1A alone is rendered much more active, being capable of digesting
185 when molecular- and activity-dependent cues are rendered nearly equal in force, they drive topograph
187 ted deletion of the cathelicidin gene, Cnlp, were rendered neutropenic prior to cutaneous infection.
188 complex in the plasma membrane, the channel is rendered non-functional because of inherent negative
189 rtance of the Ugt1 locus in mice, this locus was rendered non-functional by interrupting exon 4 to cr
190 ssed a cytoplasmic actin in Sf9 cells, which was rendered non-polymerizable by virtue of two point mu
192 the related receptor EF-Tu receptor that can be rendered nonfunctional by disruption of single glycos
193 Here we show that both Mx1 and Mx2 have been rendered nonfunctional in Odontoceti cetaceans (too
194 ed homologue for wild-type human p53 protein is rendered nonfunctional by cytoplasmic sequestration.
195 ex that facilitates miRNA-mediated silencing is rendered nonfunctional during cellular stress, includ
198 rived from host plasma membrane, the vacuole is rendered nonfusogenic with the host endolysosomal sys
202 genome could be used as a vaccine if the DNA were rendered noninfectious, we deleted the reverse tran
204 Alternatively, the infectious agent may be rendered nonpathogenic by sequestration in amyloid pl
205 transgenic mice where Ser22/23 in cTnI have been rendered nonphosphorylatable by mutation to alanine
210 Streptozotocin-induced diabetic FVB/NJ mice were rendered normoglycemic with a therapeutic mass of s
211 s were isolated from EP4(flox/flox) mice and were rendered null for the EP4 receptor with adenoCre vi
213 puts to orientation-selective ganglion cells are rendered orientation selective within the presynapti
214 ought to be unrelated to the RF ablation and was rendered pain-free after subsequent surgical treatme
215 attack frequency) was 82% and four patients were rendered pain-free for prolonged periods of time.
220 utologous CD4 T cells in which the CCR5 gene was rendered permanently dysfunctional by a zinc-finger
221 ically the two catecholaminergic groups, can be rendered persistently impaired after long-term exposu
223 rget areas of tissues or organisms that have been rendered photosensitive by genetic targeting of ChR
224 e nail material adjacent to the ablated area was rendered porous in appearance presumably due to loca
226 ating-exposure conformational cycle that has been rendered proton-independent by the gate mutations.
227 ctively downregulated and that the cells had been rendered refractory to subsequent in vivo Ag contac
228 nors carry a KDPI over 35 and have therefore been rendered relatively inaccessible to pediatric recip
229 table metastatic colorectal cancer (CRC) can be rendered resectable with systemic chemotherapy in app
230 Free RGS18 levels also rise when platelets are rendered resistant to activation by exposure to pros
231 not mediate graft-versus-host reactions and are rendered resistant to destruction by alemtuzumab.
232 which either p38alpha or p38beta kinase has been rendered resistant to the effects of specific inhib
239 on was significantly greater in patients who were rendered seizure-free, suggesting that a smaller re
241 novel lentiviral vectors (CD4-LV) that have been rendered selective for human or simian CD4(+) cells
242 iodide was used as an additive, the reaction was rendered selective for dimer formation (dimer/trimer
244 The endothelial cell line expressing vGPCR was rendered sensitive to treatment with the nucleoside
245 ly occurring, pseudoknot-insensitive viruses were rendered sensitive by the inverse K277R mutation, e
246 sistant to treatment with antibodies to VEGF were rendered sensitive in IL-17 receptor (IL-17R)-knock
248 the absence of functional GNL1, Golgi stacks were rendered sensitive to the selective ARF-GEF inhibit
251 nterface, dozens of ligand-protein complexes are rendered simultaneously to parallelize the analysis
252 nervous system, hundreds of volume channels are rendered simultaneously, whereas fluorescence intens
253 ale planar membranes of controlled size that are rendered soluble in aqueous solution via an encircli
254 cell (SBC) activity in the Mongolian gerbil is rendered sparser and more reliable by subtractive inh
255 tion and Trail Making Test Parts A and B and was rendered statistically nonsignificant by APOE epsilo
257 ST-1 is neutral, coordinated water molecules are rendered sufficiently acidic by Cu(II) to contribute
259 ransformed cells 'addicted' to AP-1 activity are rendered susceptible to SARI-mediated inhibition of
261 as found to be testosterone: male mice could be rendered susceptible to liver inflammation by castrat
262 d immunopathogenesis, WT and MyD88(-/-) mice were rendered susceptible to PcP by depletion of CD4(+)
263 horylation in three-dimensional collagen and were rendered susceptible to PLX4720 by Akt3 knockdown.
267 ated females of the plant bug Lygus hesperus are rendered temporarily unattractive by seminal fluids
268 lated position of a small moving target that was rendered temporarily invisible and whose trajectory
269 f primed animals, were expanded ex vivo, and were rendered TGF-beta insensitive by infecting with a r
270 ure and empirical knowledge, a super surface was rendered that incorporated the ideal portions from 4
275 e responding cells become fully activated or are rendered tolerant by administration of peptide Ag al
276 ough the indirect pathway of Ag presentation are rendered tolerant in molecular chimeras, transgenic
279 (BM) donors, anti-alphaGal-producing B cells were rendered tolerant in reconstituted recipients expre
281 l-), and three such Tra+ Pil- mutant strains were rendered Tra- upon deletion of virB2, indicating th
282 (bovine serum albumin, BSA) particles which were rendered transiently insoluble using a novel, reduc
284 e of kidneys with existing tumors, which may be rendered tumor free after surgical excision and recon
286 were abolished when cholangiocarcinoma cells were rendered unable to regenerate cilia by stable trans
289 SF dimer in which binding to the second site is rendered unfavorable by FMS binding at the first site
291 ) T cells in anti-CD3-conditioned recipients were rendered unresponsive, anergic, Foxp3(+), or type I
292 when intermediate states of gene expression are rendered unstable by the underlying genetic circuitr
296 indicate that the cerebral microvasculature is rendered vulnerable to thrombus formation in beta(s)
297 ate; the resulting water-soluble cages could be rendered water-insoluble through reverse anion exchan
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