ライフサイエンスコーパス: become apparent

1 of 50 degrees C before enhanced pigmentation became apparent.

2 (+) T cell responses, particularly to HASPB, became apparent.

3 acteristics particular to specific genotypes became apparent.

4 , the same age at which cognitive impairment became apparent.

5 ating DOM composition and watershed land use became apparent.

6 ional differences between the three proteins became apparent.

7 perception before microvascular pathologies become apparent.

8 any roles of the matrix are only starting to become apparent.

9 ases of imprinting and the X chromosome have become apparent.

10 al effects of HLA molecules in viral disease become apparent.

11 drogen bonds they form with hydration water, become apparent.

12 ency, the need for clinical surveillance has become apparent.

13 terial) in the genomes of healthy humans has become apparent.

14 ng T cell activation and differentiation has become apparent.

15 tably relax such that the mutational effects become apparent.

16 only recently has their role in autoimmunity become apparent.

17 fective in patients with cystic fibrosis has become apparent.

18 t distinct morbidity-related phenotypes have become apparent.

19 ttern; however, changes in the hierarchy did become apparent.

20 n human disease and regulatory processes has become apparent.

21 D8 T cells in the innate immune response has become apparent.

22 nd on the function of rheumatoid factor (RF) become apparent.

23 nd involvement of lipoprotein receptors have become apparent.

24 ology of gastrointestinal stromal tumor have become apparent.

25 uch a meaningful collision has only recently become apparent.

26 in multiple stages of T-cell development has become apparent.

27 ted truths and new layers of complexity have become apparent.

28 pair or 'heal' this damage has only recently become apparent.

29 before symptoms of Alzheimer's disease (AD) become apparent.

30 experimental and computational analyses has become apparent.

31 performance monitoring) is only beginning to become apparent.

32 ro- and eukaryotic phosphosignalling systems become apparent.

33 regulated Ca(2+) elevations and contractions become apparent.

34 formational motions in the polymerase domain becomes apparent.

35 d, the protective effect of lower Sf1 levels becomes apparent.

36 ther intestinal enzyme(s) with ARAT activity becomes apparent.

37 ipids and gluconeogenesis for growth in vivo becomes apparent.

38 king proteins and neurotransmitter receptors becomes apparent.

39 nctions of BACE1 and its close homolog BACE2 becomes apparent.

40 ch targets Rac1 for proteasomal degradation, becomes apparent.

41 en into consideration, a closer relationship becomes apparent.

42 he network of protein domain interactions is becoming apparent.

43 regulating their lifecycle is only recently becoming apparent.

44 logic, pulmonary, and metabolic diseases are becoming apparent.

45 ogen-mediated actions in the CNS is only now becoming apparent.

46 ence of epilepsy and learning disability are becoming apparent.

47 the challenges and shortfalls only recently becoming apparent.

48 and their clinical significance are only now becoming apparent.

49 ion of their targeting and assembly, are now becoming apparent.

50 hich are relevant to cancer development, are becoming apparent.

51 ectrum of advanced human cancers is just now becoming apparent.

52 d or syndromic pediatric cardiomyopathies is becoming apparent.

53 B) proteins and of calcium oscillations that became apparent 1-3 d after TNF stimulation.

54 ore treatment), 2 distinct groups of animals became apparent: (1) mice with compensated cardiac hyper

55 ymptoms compared with those without dementia became apparent 11 years (difference, 0.61; 95% CI, 0.09

56 tic sites require a conformational change to become apparent; a cryptic site can therefore be defined

57 ramolecular reorganization of photosystem II becomes apparent, accompanied by functional detachment o

58 The increased relative risk became apparent after 18 months of treatment; during the

59 Differences became apparent after 3 to 9 hours of exposure.

60 age stratification showed that RPE thinning became apparent after age 45.

61 ogressive separation of time-to-event curves became apparent after approximately 1 year of therapy.

62 ity of halothane is now well known, but only became apparent after several years of use.

63 or Gi-protein-mediated signals to BM homing became apparent after their blockade was combined with d

64 tries, medical disorders are often missed or become apparent after adoption.

65 oscopy offers some benefits to patients that become apparent after longer-term follow-up.

66 The impact of cycloheximide becomes apparent after the first peak of nuclear NF-kapp

67 Persistence of this design principle becomes apparent after the material properties are defin

68 clinical utility of these measures may only become apparent among individuals for whom levels are in

69 ymphadenectomy during radical cystectomy has become apparent and recent work has attempted to better

70 ding diversity in 5HT neuronal phenotypes is becoming apparent and is likely rooted in molecular diff

71 limitations of a rapidly growing field have become apparent, and questions regarding the quality of

72 A delay in the DOC mobilization became apparent as the ambient temperatures increased.

73 ing that the true effects of these mutations become apparent as the hierarchical level of the myofila

74 ly coalesced as the head of the pancreas has become apparent as the nidus of chronic inflammation.

75 Asymmetry quickly becomes apparent as cells in the anterior half of the eg

76 shorter post-MBT wave of transcription that becomes apparent as development proceeds.

77 in the virulence of several pathogens is now becoming apparent, as are some of the more detailed work

78 uch as geminin, cdk2, cdk4, and cytochrome c became apparent at 2 to 48 h.

79 AOM-induced ACF became apparent at approximately 4-6 weeks and continued

80 mmation and stool microbial differences only became apparent at colitis onset.

81 and spontaneous autoimmune diabetes models, became apparent at diabetes onset, and differed markedly

82 The influence of pipe material became apparent at water ages corresponding to low disin

83 In a pure diffusion model the effects become apparent at elevated calcium concentrations, e.g.

84 Differences between Tsc1/2 and Pten function become apparent at later stages.

85 ibit shortened snouts and wide-set eyes that become apparent at postnatal day 15.

86 d underlie a general locomotion deficit that becomes apparent at 12 months of age in Cln3(-/-) mice.

87 nt the effect of the cac1a null allele first becomes apparent at 3-d after flowering, when the synchr

88 yer 4 is not present in newborn kittens, but becomes apparent at about 5 weeks of age.

89 p starting at the second solvation shell and becomes apparent at the cell boundary.

90 loping interzone in the E13.5 day knee joint became apparent because these chondrocytes did not turn

91 Hypoxia-related fetal growth restriction becomes apparent between 25 and 29 wk of gestation and c

92 ffector functions, interesting analogies are becoming apparent between the two memory compartments.

93 n a more extended consolidation process that becomes apparent beyond 100 d after learning.

94 Although the functions of HDAC proteins are becoming apparent both biochemically and clinically, how

95 ns with neurological processes have recently become apparent but large gaps in our understanding stil

96 ime when cardiac morphogenesis defects first become apparent, but is expressed in an extra-embryonic

97 crease was detected only in the spinal cord, became apparent by 60 days of age (before the onset of m

98 circumference-for-age (P-interaction = 0.03) became apparent by the end of the first year of life.

99 The significance becomes apparent by, for example, the considerable incre

100 Even before dementia becomes apparent, cognitive decline may contribute to de

101 GlcN6P binding becomes apparent crystallographically when the pH is rai

102 Limitations in this approach have become apparent; decisions that were formerly based only

103 s of posture, locomotion, and sensation that became apparent during adolescence.

104 ogenesis, coordinated tissue movements first become apparent during "doming," when the blastoderm beg

105 Differential concentrations of auxin become apparent during early fruit growth, with auxin le

106 ects in actin cytoskeleton organization also become apparent during sperm individualization in dVps28

107 ncinate and inferior longitudinal fasciculi, become apparent during this period.

108 cRn targeting efficiency and lower half-life becomes apparent during analyses of T cell proliferative

109 ological complications due to the HIV itself became apparent early on in the course of the AIDS epide

110 he SNE-induced pain symptoms, an effect that became apparent following a distinct lag period of 3-4 d

111 ess, the latent proapoptotic activity of JNK becomes apparent following Dpp signaling suppression, wh

112 An "induced fit" became apparent for the side chain conformations of Arg

113 -6 D implantable collamer lens, but they did become apparent for -15 D implantable collamer lens for

114 More recently, similar roles have also become apparent for members of the ParaHox gene cluster,

115 an unprecedented, slower relaxation process becomes apparent for ac switching frequencies between 0.

116 bution for the signaling activity of K-Ras4B became apparent from recent in vivo studies, showing tha

117 shared T2D-SCA genetic basis, if any, might become apparent from better functional information about

118 evity has a strong genetic component, as has become apparent from studies with a variety of organisms

119 The scope of the methodology becomes apparent from 14 examples of orthogonally protec

120 ch FMT shows therapeutic efficacy in CDI are becoming apparent, further research is needed to underst

121 ient-specific embryonic stem (ES) cell lines became apparent, hopes began to fade for the advent of c

122 To the extent that their own perspective becomes apparent, however, it is dated, implausible, and

123 It is becoming apparent, however, that to overcome the complex

124 the developing vertebrate heart has recently become apparent; however, there is little known about th

125 It became apparent in the early days of the outbreak that t

126 Tumor heterogeneity became apparent in the form of genetically distinct subp

127 tion potential notch was absent in neonates, became apparent in the young, and was deepest in adults.

128 Such mutagenic interactions might not become apparent in higher organisms for years.

129 number polymorphism (CNP) have only recently become apparent in other organisms.

130 The stones are composed of uric acid and become apparent in the bladders as tiny stones when mice

131 yet been realized owing to bottlenecks that become apparent in the endogenous biosynthetic pathways

132 unappreciated potential open reading frames become apparent in the expression analysis, revealing an

133 ult HIV-associated nephropathy (HIVAN) would become apparent in the presence of adverse host factors.

134 HC-I molecules masks this effect, which only becomes apparent in distinct H-2 haplotypes, such as H-2

135 ary development are grossly normal, a defect becomes apparent in meiosis II when the two component sp

136 nt proceeds (e.g. by E13.5) Atoh1 expression becomes apparent in the dorsal midline in the region of

137 Clinically, variably severe anemia becomes apparent in the first year accompanied by occasi

138 d softening, causing the Mullins effect that becomes apparent in TPUs even at moderate tensile strain

139 mice develop normally, but lens degeneration becomes apparent in young adult mice.

140 in the past 10 years, and peanut allergy is becoming apparent in Africa and Asia.

141 e interstitial cells at the early stage, and became apparent later in both interstitial and tubular c

142 that may result in functional deficits that become apparent later in life.

143 The main manifestations of RIHD become apparent many years after treatment and include c

144 The importance has become apparent of several paracrine and autocrine signa

145 of transformation, when contrast enhancement became apparent on T1-weighted images.

146 en who initiated therapy closer to menopause became apparent only after 6 years of use.

147 selected number of genetic alterations that became apparent only at the MRD stage.

148 This difference became apparent only through a series of experiments, es

149 s of the Affordable Care Act, financial ties became apparent only through self-disclosure.

150 defects by PDF knockdown are presynaptic and become apparent only after metamorphosis, highlighting a

151 he symptoms of ovarian cancer are subtle and become apparent only during advanced stages of the disea

152 efits from bigeye conservation measures will become apparent only in the 2030s, assuming timely imple

153 tive binding sites in protein receptors that become apparent only when an inhibitor binds, and correc

154 any of these subtle analytical problems have become apparent only when studying the more complex vert

155 trophin from birth; however, muscle weakness becomes apparent only at 3-5 years of age, which happens

156 s makes for a complex picture that will only become apparent over decades.

157 sone or immunosuppressive agents, but it has become apparent over the last 20 years that a substantia

158 s different from uninfected inflammation and becomes apparent prior to expression of the clinical sep

159 of mechanics on cell and tissue function is becoming apparent, raising the question: how does the ai

160 f risk and prevalence in the population have become apparent: rare high-penetrance alleles, rare mode

161 Resolution of HE became apparent sometime after month 6 in ranibizumab-tr

162 On review, it became apparent that a combination of high-dose propofol

163 the earlier results obtained with CN3718, it became apparent that CodY regulation of sporulation vari

164 clinical and research PET/CT methodology, it became apparent that data acquisition and processing app

165 It became apparent that gene death likely resulted in the l

166 More recently it became apparent that Gram-positive bacteria also express

167 of recombinant Ig-based bnAb structures, it became apparent that key functional features of bnAbs of

168 However, it soon became apparent that P-glycoprotein was not expressed in

169 First, it became apparent that serine phosphorylation of IRS prote

170 However, it became apparent that some human disease related targets

171 P cleavage product Abeta, in recent years it became apparent that the APP intracellular domain (APP-I

172 First, it became apparent that the complexity of the viral populat

173 nal replacement therapy became available, it became apparent that the mode of death of patients with

174 two recently published rumen metagenomes, it became apparent that the rumen plasmidome codes for func

175 Based on this analysis, it became apparent that the turn introduced into a designed

176 In the past decades, it became apparent that they would be able to protect again

177 min D metabolism and function since it first became apparent that this factor was required for bone h

178 and following their use as antimicrobials it became apparent that this group of antibiotics also poss

179 It will become apparent that a mixture of descriptions is likely

180 However, it has become apparent that a new natural history is being defi

181 Although it has become apparent that acute myeloid leukemia (AML) is hig

182 However, over the last decade, it has become apparent that alternative physiologic mechanisms

183 Over the last 2 decades, it has become apparent that AMPK regulates several other cellul

184 However, it has become apparent that amyloid fibrils and oligomers assem

185 In recent years, it has become apparent that biallelic mutations in some of thes

186 required for the apoptotic phenotype, it has become apparent that cells frequently die even when casp

187 ively for their psychoactive effects, it has become apparent that certain cannabinoids possess immuno

188 erved with CO, in the past five years it has become apparent that CO has been ascribed an additional

189 If it were to become apparent that dangerous changes in global climate

190 munogenicity of individual HLA eplets.It has become apparent that epitope-based matching is superior

191 More recently, it has become apparent that ethanol consumption also leads to i

192 In recent years, it has become apparent that future crop improvement efforts wil

193 It has become apparent that given the recent advances in chemis

194 In recent times, it has become apparent that heterogeneous populations of dendri

195 In the past several years, it has become apparent that human papillomavirus is an importan

196 It has now become apparent that ILCs play more complex roles throug

197 In recent years, it has become apparent that in positive-strand RNA plant viruse

198 tory streaming paradigm, and recently it has become apparent that instead of making one fixed percept

199 y generated considerable interest, as it has become apparent that it is present in the mammalian brai

200 of acquired and genetic defects, and it has become apparent that many gastrointestinal cancers origi

201 fusions in real time in living cells it has become apparent that many of these complexes are not fix

202 rs directly measure protons, it has recently become apparent that many pH-sensing systems measure pH

203 In recent years, it has become apparent that microbial signals can be generated

204 It has become apparent that much of cellular metabolism is cont

205 Furthermore, it has become apparent that much of this life is dependent on l

206 It has recently become apparent that multiple layers of regulation exist

207 It has only recently become apparent that mutations in epigenetic mechanisms

208 It has recently become apparent that mutations in nuclear-encoded compon

209 Recently it has become apparent that N = 2 supersymmetric quantum field

210 Recently, it has become apparent that Nematostella may be a particularly

211 However, it has become apparent that new classes of allosteric inhibitor

212 Furthermore, as it has become apparent that NMDAR-mediated signaling is depende

213 It has recently become apparent that OmpR functions as a global regulato

214 More recently, it has become apparent that one also has to study continuous di

215 Recently, it has become apparent that other DNA modifications, such as th

216 Despite this, it has become apparent that our initial understanding of AT1R s

217 It has now become apparent that Ox-PL affects multiple genes and pa

218 In particular, it has become apparent that patients with ERA have the best cha

219 It has become apparent that pharyngeal endoderm plays an import

220 Over the years, it has become apparent that Plasmodium falciparum exerts limite

221 Recently, it has become apparent that protection against disease correlat

222 Recently, it has become apparent that proteins that make up and modulate

223 It has become apparent that skin manifestations are an importan

224 Recently, however, it has become apparent that some self-reactive T cells avoid be

225 Recently, it has become apparent that superficial vein thrombosis (SVT) c

226 It has become apparent that T cells require growth signals to m

227 It has only recently become apparent that the bioconversion of traditional di

228 It has become apparent that the cardinal feature of achalasia,

229 In the last decade, it has become apparent that the clinical burden of NAFLD is not

230 Over the last decade, it has become apparent that the complex interactions between co

231 may receive a different diagnosis or it may become apparent that the diagnosis could have been made

232 It has recently become apparent that the genes for the biosynthesis of n

233 It has recently become apparent that the gut microbiota modulates the re

234 However, in the past few decades it has become apparent that the human milk oligosaccharides are

235 It has become apparent that the immune system evolved multiple

236 However, it has recently become apparent that the kindlin family of FERM domain p

237 However, in recent years it has become apparent that the microbiota has profound effects

238 Over the past decade, it has become apparent that the nucleus is tightly integrated i

239 Over the past few years, it has become apparent that the ontogeny and maturation of thes

240 eiving considerable attention because it has become apparent that their individual functions are not

241 As this research has progressed, it has become apparent that there is considerable overlap betwe

242 Recently, it has become apparent that there is significant crosstalk betw

243 It has become apparent that these biological responses are regu

244 s in cell-cycle progression, it has recently become apparent that they differ in tissue-specific func

245 It has become apparent that this pathway interacts with a varie

246 xation from an isometric contraction, it has become apparent that this slowing is indicative of funct

247 In recent years, it has become apparent that this tissue destruction is associat

248 At the same time, it has become apparent that, as a result of the natural history

249 to put complementary codons face-to-face, it becomes apparent that the code displays latent mirror sy

250 Taken together, it becomes apparent that understanding the effects of speci

251 cterization of the 7TM receptors (GPCRs), it becomes apparent that, through much of eukaryotic evolut

252 Increasingly, however, it is becoming apparent that certain pyruvate esters, includin

253 aches have been probed clinically, but it is becoming apparent that combinations of cells and scaffol

254 It is becoming apparent that each gene/locus is heterogeneous

255 Not surprisingly, it is also becoming apparent that epigenetics is intimately involve

256 to treat more wide-ranging disorders, it is becoming apparent that for many conditions laparoscopy s

257 ly affected by age-related changes and it is becoming apparent that immune memory exhibits significan

258 It is becoming apparent that infections by a major class of vi

259 eep larvae close to natal populations, it is becoming apparent that larval behaviors in a broader spe

260 se archetypal axon guidance molecules, it is becoming apparent that molecules previously known for th

261 As more data emerge, it is becoming apparent that one important aspect of such an i

262 It is now becoming apparent that other factors give filaments a sp

263 Moreover, it is becoming apparent that proteins, organelles, and pathoge

264 rhaps best understood in bacteria, but it is becoming apparent that replicative barriers associated w

265 It is, however, becoming apparent that sex differences in substance depe

266 However, it is also becoming apparent that some cancer cells move in an amoe

267 en in many patients with these agents, it is becoming apparent that some patients with high genomic r

268 Finally, it is becoming apparent that the clinical impact of B-cell dep

269 nse has been well established, but it is now becoming apparent that the phosphorylation state of Hsp2

270 s of the materials are being explored, it is becoming apparent that the photovoltaic performance of t

271 RECENT FINDINGS: It is becoming apparent that the skin inflammation alone has i

272 It is becoming apparent that there is a strong link between ta

273 tations that are strikingly different, it is becoming apparent that these mutations recurrently hijac

274 Two perspectives on risk taking became apparent: the procedure-centric perspective descr

275 50 K, below which antiferromagnetic coupling becomes apparent; the compound has a room-temperature si

276 However, before these abnormalities become apparent, there are functional deficits in contra

277 It is becoming apparent, therefore, that many important functi

278 In mammals, long-range gene regulation became apparent through simple Mendelian disease genetic

279 ight explained the original symptoms, rarely became apparent to the patient's primary care doctor in

280 he true cost of proposed development actions becomes apparent to decision makers.

281 h suggested enhanced oxygen extraction, that became apparent toward the end of the 45-min absorption

282 MT1-MMP islets become apparent upon podosome dissolution and persist be

283 tectable in direct human-teleost comparisons become apparent using gar: functional studies uncovered

284 Short-term potentiation only became apparent when a neuron was connected to another n

285 x along their length, and these changes only became apparent when mass-per-length (MPL) determination

286 h growth on plastic, significant differences became apparent when one compared the relative ability o

287 rmined whether differences in neutralization become apparent when antibodies to gB, gD, or gH/gL are

288 that is, sites on protein targets that only become apparent when drugs bind, provide a promising alt

289 ndomization studies, particularly those that become apparent when the analogy with randomized control

290 However, this function only becomes apparent when other processing enzymes are absen

291 This vastly underappreciated capability becomes apparent when prelinguistic vocalizations expres

292 possible inhibitory role for Tyr-225, which becomes apparent when Tyr-219 is mutated.

293 let of three histidines (H27, H30, and H180) became apparent, which was subsequently confirmed by sit

294 tion, considerable charge-transfer character becomes apparent, which rationalizes the origin of huge

295 However, the limitation of this model became apparent with the discovery that Ras and ERK can

296 trapped air, at an early stage, before they become apparent with other diagnostic tests.

297 ances in the low parts-per-million range but become apparent with the consideration of additional met

298 ngs, bones, and cardiovascular system, which becomes apparent with increasing age.

299 Ethnic differences are becoming apparent, with aggressive subtypes being observ

300 plained roles of other conserved nucleotides become apparent within the context of a distinctly new f