ライフサイエンスコーパス: branched-chain amino acid

1 biosynthetic enzymes for heme, cysteine, and branched chain amino acids.

2 proteins that is responsive to both GTP and branched chain amino acids.

3 olderia pseudomallei that is auxotrophic for branched chain amino acids.

4 rolyzing (PGPH) but also cleaves bonds after branched chain amino acids.

5 n allele of BAP2 that encodes a permease for branched chain amino acids.

6 nvolved in the metabolism of fatty acids and branched chain amino acids.

7 lycolysis/gluconeogenesis, and metabolism of branched chain amino acids.

8 ed esters arising from partial catabolism of branched chain amino-acids.

9 by AMP deaminase 3 (Ampd3) and catabolism of branched-chain amino acids.

10 lag in growth when nutritionally limited for branched-chain amino acids.

11 tin, C-reactive protein, acylcarnitines, and branched-chain amino acids.

12 protein, E1alpha phosphorylation, and plasma branched-chain amino acids.

13 anscriptional regulator that is activated by branched-chain amino acids.

14 known as yhdG) that encodes a transporter of branched-chain amino acids.

15 etabolites through its activation by GTP and branched-chain amino acids.

16 ain transporters that accumulate proline and branched-chain amino acids.

17 BkdR likely responds to the presence of branched-chain amino acids.

18 ently by altering the intracellular level of branched-chain amino acids.

19 nd sugars, and the genes for biosynthesis of branched-chain amino acids.

20 nd enhanced levels of volatiles derived from branched-chain amino acids.

21 rved between patients who received high-dose branched-chain amino acids (222 mg/kg of body weight t.i

22 spring than in the control subjects, whereas branched-chain amino acids (343 +/- 54 vs. 357 +/- 54 mi

23 ncies and growth restriction associated with branched-chain amino acid accumulation and (ii) energy d

24 assic maple syrup urine disease pups reduced branched-chain amino acid accumulation in milk as well a

25 o repress transcription, suggesting that the branched-chain amino acids act as inducers rather than c

26 Changes in branched-chain amino acids after MI were associated with

27 istently higher content of free amino acids (branched-chain amino acids, alanine, serine, glycine, pr

28 (E. coli aspartate aminotransferase, E. coli branched-chain amino acid aminotransferase, and Bacillus

29 he first 2 enzymes in the catabolic pathway--branched-chain-amino-acid aminotransferase (BCAT) and br

30 -well plate spectrophotometric assay for the branched-chain amino acid aminotransferases is described

31 In addition, (1)H MRS showed an increase in branched chain amino acid and alanine concentrations.

32 acid metabolism were evident from increased branched chain amino acid and asparagine levels and alte

33 r metabolite biomarkers of diabetes, such as branched chain amino acids and aromatic amino acids, sug

34 S. aureus CodY was activated in vitro by the branched chain amino acids and GTP, CodY appears to link

35 and proteins, including ones in pathways of branched-chain amino acid and fatty acid metabolism and

36 ystal structure of the GAF domain of CodY, a branched-chain amino acid and GTP-responsive regulator o

37 Here, we highlight collaboration in branched-chain amino acid and pantothenate (vitamin B5)

38 olutionary age analysis revealed that, while branched-chain amino acid and proline catabolism are ver

39 cumulation as well as circulating cytokines, branched-chain amino acids and acylcarnitines in the pat

40 Circulating branched-chain amino acids and aromatic amino acids were

41 e with low FENO, had higher levels of plasma branched-chain amino acids and bile acids.

42 Therefore, the L-branched-chain amino acids and D-leucine are the inducer

43 to MS, we detected significant increases in branched-chain amino acids and intermediates of arginine

44 d organic acidosis caused by accumulation of branched-chain amino acids and lactic acid.

45 abolism, ETHE1 also affects the oxidation of branched-chain amino acids and lysine.

46 resulting in accumulation of fatty acids and branched-chain amino acids and oncogenic mTOR activation

47 olic acidosis, stimulates the degradation of branched-chain amino acids and proteins and therefore bl

48 Binding studies with branched-chain amino acids and their analogs revealed th

49 n family are involved in the biosynthesis of branched-chain amino acids and/or in the Met chain elong

50 n, by cleaving mainly bonds after acidic and branched chain amino acids, and accelerates the degradat

51 Ceramides, lysolipids, aromatic amino acids, branched chain amino acids, and stress-induced amino aci

52 etic performance in this group are creatine, branched-chain amino acid, and beta-hydryoxy-beta-methyl

53 thesized that protein, essential amino acid, branched-chain amino acid, and leucine intakes are assoc

54 mulates amino acid oxidation, chiefly of the branched-chain amino acids, and ammonia production in pr

55 and the catabolism of odd-chain fatty acids, branched-chain amino acids, and cholesterol.

56 Total indispensable amino acids, branched-chain amino acids, and glutamine declined 25% o

57 -density lipoprotein lipids, glucose levels, branched-chain amino acids, and inflammatory markers.

58 luding diacylglycerols and triacylglycerols, branched-chain amino acids, and markers reflecting metab

59 Branched chain amino acids are particularly effective in

60 s subtilis operon (ilvB) for biosynthesis of branched-chain amino acids are subject to multiple mecha

61 Evidence is accumulating that L-branched-chain amino acids are the inducers of the opero

62 sted the effects of a genetic determinant of branched-chain amino acid/aromatic amino acid ratio on c

63 We genotyped the branched-chain amino acid/aromatic amino acid ratio-asso

64 Individuals carrying the C allele of the branched-chain amino acid/aromatic amino acid ratio-asso

65 e-dependent decarboxylating enzyme that uses branched-chain amino acids as substrate.

66 nvolved with biosynthesis and degradation of branched-chain amino acids, as well as in the production

67 eases, indicating a coordinate regulation of branched-chain amino acids at a post-mRNA level.

68 convergence of microRNAs and TFs within the branched chain amino acid (BCAA) metabolic pathway, poss

69 electrophoresis (MD-CE) assay for monitoring branched chain amino acid (BCAA) uptake/release dynamics

70 Lung tumors catabolize circulating branched chain amino acids (BCAA) to extract nitrogen fo

71 rsity includes: inflammation, degradation of branched chain amino acids (BCAA), and regulation of per

72 CodY is a branched-chain amino acid (BCAA) and GTP sensor and a gl

73 synthase (AHAS) catalyzes the first step of branched-chain amino acid (BCAA) biosynthesis, a pathway

74 cetohydroxyacid synthase (AHAS) required for branched-chain amino acid (BCAA) biosynthesis.

75 three Bacillus subtilis operons involved in branched-chain amino acid (BCAA) biosynthesis.

76 e (BCKDH) catalyzes the critical step in the branched-chain amino acid (BCAA) catabolic pathway and h

77 We previously described abnormalities in the branched-chain amino acid (BCAA) catabolic pathway as a

78 Branched-chain amino acid (BCAA) catabolism is regulated

79 augment BCKDC flux have been shown to reduce branched-chain amino acid (BCAA) concentrations in vivo.

80 enylbutyrate administration decreases plasma branched-chain amino acid (BCAA) concentrations, and pre

81 Carbohydrate (CHO) or branched-chain amino acid (BCAA) feedings may attenuate

82 of primary brain astrocytes with either the branched-chain amino acid (BCAA) isoleucine or the BCAA

83 Branched-chain amino acid (BCAA) metabolism plays a cent

84 tablish an accurate molecular model of human branched-chain amino acid (BCAA) metabolism, the distrib

85 posed cells are either supplemented with the branched-chain amino acids (BCAA) anaerobically or retur

86 its and enzymes involved in the oxidation of branched-chain amino acids (BCAA) and fatty acids (e.g.,

87 The branched-chain amino acids (BCAA) are essential amino ac

88 ldup of branched-chain keto-acids (BCKA) and branched-chain amino acids (BCAA) in body fluids (e.g. k

89 een associated with a selective reduction in branched-chain amino acids (BCAA) in spite of adequate d

90 does not grow in minimal medium lacking the branched-chain amino acids (BCAA) leucine or valine but

91 duced muscle expression of genes involved in branched-chain amino acids (BCAA) metabolism.

92 are enzymes that initiate the catabolism of branched-chain amino acids (BCAA), such as leucine, ther

93 orphology and higher levels of ketogenic and branched-chain amino acids (BCAA).

94 ith varying doses of leucine or a mixture of branched chain amino acids (BCAAs) on myofibrillar prote

95 Branched chain amino acids (BCAAs) play critical roles i

96 High-protein diets, rich in methionine and branched chain amino acids (BCAAs), apparently reduce li

97 reductions were seen in the concentration of branched chain amino acids (BCAAs), which are key precur

98 tissue can metabolize substantial amounts of branched chain amino acids (BCAAs).

99 esized that a greater decline in circulating branched-chain amino acids (BCAAs) after weight loss ind

100 Circulating branched-chain amino acids (BCAAs) and aromatic amino ac

101 Circulating amino acids, such as branched-chain amino acids (BCAAs) and aromatic amino ac

102 We find that elevated plasma levels of branched-chain amino acids (BCAAs) are associated with a

103 Branched-chain amino acids (BCAAs) are synthesized in pl

104 Branched-chain amino acids (BCAAs) are three of the nine

105 The branched-chain amino acids (BCAAs) are vital to both gro

106 mportant for acid adaptation, as turnover of branched-chain amino acids (bcAAs) could provide importa

107 the same initiating events, these tumors use branched-chain amino acids (BCAAs) differently.

108 The branched-chain amino acids (BCAAs) Ile, Val, and Leu are

109 demiological and experimental data implicate branched-chain amino acids (BCAAs) in the development of

110 have previously shown that the limitation of branched-chain amino acids (BCAAs) is a cue that induces

111 the pools of specific metabolites, i.e., the branched-chain amino acids (BCAAs) isoleucine, leucine,

112 The branched-chain amino acids (BCAAs) Leu, Ile, and Val are

113 Complete oxidation of the branched-chain amino acids (BCAAs) leucine, isoleucine (

114 The branched-chain amino acids (BCAAs) leucine, isoleucine,

115 In the brain, catabolism of the branched-chain amino acids (BCAAs) provides nitrogen for

116 That is, branched-chain amino acids (BCAAs) served as more potent

117 The branched-chain amino acids (BCAAs) valine, leucine and i

118 Therefore, the branched-chain amino acids (BCAAs), especially leucine,

119 Dietary supplementation with branched-chain amino acids (BCAAs), including leucine, i

120 that BCAT1, a cytosolic aminotransferase for branched-chain amino acids (BCAAs), is aberrantly activa

121 Branched-chain amino acids (BCAAs), particularly leucine

122 ed in the oxidation of fatty acids (FAs) and branched-chain amino acids (BCAAs), senses nutrients and

123 g healthy mice a diet with reduced levels of branched-chain amino acids (BCAAs), which are associated

124 the enzyme that initiates the catabolism of branched-chain amino acids (BCAAs).

125 interaction with its effectors, GTP and the branched-chain amino acids (BCAAs).

126 Higher circulating levels of the branched-chain amino acids (BCAAs; i.e., isoleucine, leu

127 Branched-chain amino acids (BCAAs; leucine, isoleucine a

128 Branched-chained amino acids (BCAAs) (Leu, Ile, and Val)

129 insulin were to reduce plasma levels of the branched chain amino acids (BCAs) leucine/isoleucine and

130 t differences in the amounts of aromatic and branched chain amino acids between the groups as well as

131 ed a significant difference in the levels of branched-chain amino acids between the wild type and Del

132 SBPs, which had been previously annotated as branched-chain amino-acid-binding proteins.

133 onal yeast mitochondrial enzyme required for branched chain amino acid biosynthesis and for the stabi

134 egulates the expression of genes involved in branched chain amino acid biosynthesis and in ammonia as

135 For example, Ilv5 is required for branched chain amino acid biosynthesis and mtDNA stabili

136 Tpk1 is required for the derepression of branched chain amino acid biosynthesis genes that seem t

137 The mathematical model of branched chain amino acid biosynthesis in E. coli K12 pr

138 ted by isoleucine and valine binding control branched chain amino acid biosynthesis in Escherichia co

139 mitochondrial protein that also functions in branched chain amino acid biosynthesis, and one or more

140 ein in Saccharomyces cerevisiae required for branched-chain amino acid biosynthesis and for the stabi

141 halts bacterial growth via inhibition of the branched-chain amino acid biosynthesis enzyme dihydroxya

142 ynthase (ALS) is the first committed step of branched-chain amino acid biosynthesis in plants and bac

143 and raised the root and shoot levels of the branched-chain amino acid biosynthesis intermediate 2-ox

144 cid synthase (AHAS), the first enzyme in the branched-chain amino acid biosynthesis pathway.

145 . 2.2.1.6), which is the first enzyme in the branched-chain amino acid biosynthesis pathway.

146 ctively catalyze the first committed step of branched-chain amino acid biosynthesis, but ilvG is uniq

147 ains lacking a YjgF homolog have a defect in branched-chain amino acid biosynthesis.

148 yme reactions and regulatory circuits of the branched chain amino acid biosynthetic pathways, includi

149 pA have been shown to regulate expression of branched-chain amino acid biosynthetic genes, suggesting

150 2 skeletal muscle had increased oxidation of branched chain amino acids but decreased oxidation of fa

151 ues essential for full activation of CodY by branched-chain amino acids, but these residues are not c

152 These data led to the discovery of impaired branched chain amino acid catabolic enzyme isovaleryl-Co

153 ylase, and 3-methylcrotonyl-CoA carboxylase (branched chain amino acids catabolism).

154 by metformin exposure, including changes in branched-chain amino acid catabolism and cuticle mainten

155 Thus, ARF increases branched-chain amino acid catabolism by activating BCKAD

156 hat several Arabidopsis mutants deficient in branched-chain amino acid catabolism or fatty acid metab

157 It also increases our knowledge of the role branched-chain amino acid catabolism plays in seed devel

158 the activity of the rate-limiting enzyme for branched-chain amino acid catabolism, branched-chain ket

159 ogenase (BCKAD), the rate-limiting enzyme in branched-chain amino acid catabolism, in adrenalectomize

160 Increased plasma branched-chain amino acid concentrations are associated

161 Indispensable and branched-chain amino acid concentrations were restored w

162 Branched-chain amino acids constitute a novel, safe trea

163 the identification and characterization of a branched-chain amino acid decarboxylase, which would app

164 detection of the major CoA-intermediates of branched chain amino acid degradation in biological samp

165 rior to this study, the relationship between branched-chain amino acid degradation (named for leucine

166 Furthermore, the Hadza GM is equipped for branched-chain amino acid degradation and aromatic amino

167 oteins: the H-protein and the E2 subunits of branched chain amino acid dehydrogenase (BCDH) and alpha

168 amino acids for colonization, acquisition of branched-chain amino acids does not appear to be a deter

169 tend beyond a role for binding and acquiring branched-chain amino acids during commensalism.

170 tion of the kinetic assay for "clamping" the branched-chain amino acids during hyperinsulinemic eugly

171 r very-low-density lipoprotein measures, and branched-chain amino acids (e.g., leucine OR = 2.94, 2.5

172 erprints of severe obesity were aromatic and branched-chain amino acids (elevated), metabolites relat

173 d redirect metabolism for the utilization of branched-chain amino acids for energy, carbon, and perha

174 sted that Ca. C. thermophilum may synthesize branched-chain amino acids from an intermediate(s) of th

175 lude testosterone analogues, growth hormone, branched chain amino acid, glutamine, arginine, creatine

176 tor of the proteasomal protease that prefers branched-chain amino acids had less of an effect on cata

177 Branched-chain amino acids have been reported to improve

178 le genome-wide association studies (GWAS) on branched-chain amino acids have identified some regulato

179 The catabolic pathways of branched-chain amino acids have two common steps.

180 ys an important role in regulating levels of branched chain amino acids in seeds.

181 a 2-h growth arrest caused by starvation for branched-chain amino acids in an E. coli K-12 relA1 stra

182 d to increased circulating concentrations of branched-chain amino acids in fasting.

183 reported to confer transport of proline and branched-chain amino acids in in vitro expression system

184 ermines the total concentration of all three branched-chain amino acids in plasma within 1 min.

185 confirm an important role for catabolism of branched-chain amino acids in T2D and IFG.

186 f the authors, that focus on the role of the branched-chain amino acids in the regulation of mRNA tra

187 The efficacy of the branched-chain amino acids in the treatment of tardive d

188 to GTP in vitro but also responded poorly to branched-chain amino acids in vitro unless GTP was simul

189 atable by GTP but to a much lesser extent by branched-chain amino acids in vitro.

190 yme inhibitors and the rich concentration of branched-chain amino acids in whey, which act synergisti

191 The catabolic pathway for branched-chain amino acids includes deamination followed

192 Addition of L-branched-chain amino acids increased the susceptibility

193 Because mammals do not synthesize branched-chain amino acids, inhibition of dihydroxyacid

194 zyme's substrate and stereospecificity for L-branched chain amino acids is a group of hydrophobic res

195 Accumulation of free isoleucine and other branched-chain amino acids is greatly elevated in respon

196 hypothesis that raised plasma levels of the branched-chain amino acids isoleucine, leucine, and vali

197 reased in presymptomatic HD sheep, including branched chain amino acids (isoleucine, leucine and vali

198 l transcriptional regulator that responds to branched-chain amino acids (isoleucine, leucine, and val

199 metabolic precursors (i.e., fatty acids and branched-chain amino acids), isotope labeling analyses s

200 ficits in enzymes required for catabolism of branched chain amino acids, ketones, and lactate, along

201 gulated pathways for the biosynthesis of the branched chain amino acids L-isoleucine, L-valine, and L

202 Branched-chain amino acids L-isoleucine, L-leucine, and

203 ng several involved in the metabolism of the branched-chain amino acids, L-isoleucine, L-valine, and

204 ave been the subject of great scrutiny, as a branched-chain amino acid, Leu can be catabolized within

205 l amino acid phenylalanine and the essential branched chain amino acids leucine, isoleucine, and vali

206 The branched chain amino acids leucine, isoleucine, valine,

207 Recent findings have demonstrated that the branched-chain amino acid leucine can activate the trans

208 The branched-chain amino acid leucine is an essential nutrie

209 the ability of nutrients, in particular the branched-chain amino acid leucine, to activate mTOR inde

210 The branched-chain amino acids leucine and isoleucine lower

211 ally inherited disorder in the catabolism of branched-chain amino acids leucine, isoleucine, and vali

212 icantly raised the circulating levels of the branched-chain amino acids leucine, isoleucine, and vali

213 te that essential amino acids, in particular branched-chain amino acids (leucine, valine, and isoleuc

214 The branched-chain amino acid, leucine, also exerts similar

215 ent of infections were associated with lower branched chain amino acid levels (P<0.01 and <0.001, res

216 Lower preoperative handgrip strength and branched chain amino acid levels are associated with lon

217 We propose that amino acids, in particular branched-chain amino acids, may promote beta-cell prolif

218 e disease (MSUD) is an inherited disorder of branched chain amino acid metabolism presenting with neo

219 raight short-chain-length FAs originate from branched chain amino acid metabolism, and serve as prime

220 ter has an in vivo role in the regulation of branched chain amino acid metabolism.

221 F1F0-ATPase system, fatty acid biosynthesis, branched chain amino acids metabolism), and molecular ch

222 Adiponectin corrected the altered branched-chain amino acid metabolism caused by HFD and c

223 The subcellular sites of branched-chain amino acid metabolism in plants have been

224 nces of acidification and glucocorticoids on branched-chain amino acid metabolism in specific organs

225 e disease (MSUD) is an inherited disorder of branched-chain amino acid metabolism presenting with lif

226 nning on page 434) defined a new disorder of branched-chain amino acid metabolism resembling human ma

227 zed the condensation of two intermediates in branched-chain amino acid metabolism, isovaleryl-Coenzym

228 tion of proteins in fatty acid oxidation and branched-chain amino acid metabolism.

229 e A (CoA) transfer to isoleucine and reduced branched-chain amino acid metabolism.

230 ) is a rare, autosomal recessive disorder of branched-chain amino acid metabolism.

231 ex and formation of a metabolic unit (termed branched-chain amino acid metabolon) that can be influen

232 ained before and 7 hours after a single oral branched chain amino acid mixture enriched with leucine

233 nsulin resulted in increased plasma glucose, branched chain amino acids, nonesterified fatty acids, b

234 Neither essential amino acids, branched-chain amino acids, nor any individual amino aci

235 l or venous plasma total, indispensable, and branched-chain amino acids of 125-144% by day 5 only in

236 Substrate DNA, BkdR, and any of the L-branched-chain amino acids or D-leucine was required for

237 dyskinesia were randomly assigned to receive branched-chain amino acids or placebo.

238 ymes to starvation for aromatic amino acids, branched-chain amino acids, or methionine.

239 ociated with multiple metabolites, including branched-chain amino acids, other hydrophobic amino acid

240 of the BCKDC, promotes metabolon formation, branched-chain amino acid oxidation, and cycling of nitr

241 ehydrogenase (PDH) as well as fatty acid and branched-chain amino acid oxidation.

242 This stimulatory effect is largely due to branched chain amino acids, particularly leucine, and ca

243 arget of rapamycin (mTOR), through which the branched-chain amino acids, particularly leucine, act to

244 The branched-chain amino acid pathways are extended to produ

245 he general amino acid permease (Aap) and the branched-chain amino acid permease (Bra) of Rhizobium le

246 solute transport systems: PA1971 (braZ) for branched-chain amino acids permease; PA2042 for a putati

247 designated as chymotrypsin-like (ChT-L) and branched chain amino acid preferring (BrAAP) cleave bond

248 ity, but not Z-GPFL-CHO, an inhibitor of the branched chain amino acid preferring component, prevente

249 , cleaving after hydrophobic residues, and a branched chain amino acid-preferring component (BrAAP),

250 CodY is a branched-chain amino acid-responsive transcriptional reg

251 The addition of branched-chain amino acids restored growth, indicating t

252 Furthermore, branched-chain amino acids retain their ability to induc

253 es of cardiovascular disease risk (including branched-chain amino acids, select unsaturated lipid spe

254 Interestingly, branched-chain amino acids stimulate phosphorylation of

255 Branched-chain amino acids, such as leucine and glucose,

256 gion was enhanced in the presence of GTP and branched-chain amino acids, suggesting a link between nu

257 Branched-chain amino acids supplement may be helpful in

258 Branched chain amino acid supplements may be of value in

259 th microbial function; 13 pathways including branched chain amino acid synthesis were significantly e

260 ctional gene classes, including aromatic and branched-chain amino acid synthesis, ribosomal proteins,

261 talyses the transfer of the amino group from branched-chain amino acids to alpha-ketoglutarate (alpha

262 e-long dietary restriction and monitoring of branched-chain amino acids to avoid brain injury.

263 at rapamycin (25 nM) inhibits the ability of branched-chain amino acids to stimulate the phosphorylat

264 IDH1 mutation and decreased activity of the branched-chain amino acid transaminase 1 (BCAT1) enzyme.

265 how that glioblastoma express high levels of branched-chain amino acid transaminase 1 (BCAT1), the en

266 on of its direct targets including the BCAT2 branched-chain amino acid transaminase 2) gene.

267 s well as single-nucleotide polymorphisms in branched-chain amino-acid transaminase 1 (BCAT1) and phe

268 was identified as a potential biomarker for branched chain amino acid transferase inhibitor activity

269 n with a chromosomal interval containing two branched-chain amino acid transferases, BCAT1 and BCAT2.

270 of the leucine, isoleucine, and valine (LIV) branched-chain amino acid transport system, reduced the

271 Despite each LIV protein being required for branched-chain amino acid transport, only the LivJ and L

272 rst gene of an operon apparently involved in branched-chain amino acid transport.

273 ase in acetate, lactate, succinate, alanine, branched chain amino acids, trimethylamine and a progres

274 ultivariate analyses identified preoperative branched-chain amino acid/tyrosine ratio (BTR) <5, alani

275 howed severe disturbance in the synthesis of branched-chain amino acids upon treatment with imazapyr.

276 Reduced branched-chain amino acid uptake and increased accumulat

277 Concentrations of the branched-chain amino acids valine, isoleucine, and leuci

278 Products from the degradation of the branched-chain amino acids valine, leucine, and isoleuci

279 abolic disorder, affecting the metabolism of branched chain amino-acids (Valine, Leukine, Isoleukine)

280 Genes for the synthesis of branched-chain amino acids (valine, isoleucine and leuci

281 bunit, that cleaves bonds after aromatic and branched chain amino acids was designated as chymotrypsi

282 nd liver, the two major tissues that degrade branched-chain amino acid was measured.

283 Accumulation of the branched-chain amino acids was accompanied by a 24-fold

284 elevated blood lactate, pyruvate, and plasma branched-chain amino acids was diagnosed with dihydrolip

285 g to the intracellular levels of GTP and the branched-chain amino acids, was previously shown to be a

286 of CodY with various levels of activation by branched-chain amino acids, we concluded that unliganded

287 By altering the availability of branched-chain amino acids, we further demonstrated CodY

288 Branched-chain amino acids were almost inactive, and cha

289 Prominent changes in branched-chain amino acids were observed after 1 week of

290 Basal plasma leucine and branched-chain amino acids were reduced in LTx-5, LTx-13

291 Concentrations of branched-chain amino acids were similar in breast-fed in

292 coneogenesis and oxidations of glutamine and branched chain amino acids, which together sustain the n

293 Leucine (Leu) is an essential branched-chain amino acid, which activates the mammalian

294 BCAT1 catalyzes the transamination of branched-chain amino acids while converting alpha-ketogl