ライフサイエンスコーパス: cataract

1 terior capsule opacification (PCO; secondary cataract).

2 ffects (e.g., elevated intraocular pressure, cataracts).

3 was not associated with an increased risk of cataract.

4 in patients with vitreoretinal diseases and cataract.

5 he relationships of HBV and HCV infection to cataract.

6 ignificantly associated with nuclear and any cataract.

7 genes in lens cells that could contribute to cataract.

8 therapeutic intervention for human diabetic cataract.

9 ologic anomalies, such as microphthalmia and cataract.

10 nanophthalmic eyes with visually significant cataract.

11 in preventing ocular complications, such as cataract.

12 ated for the development of vision-affecting cataract.

13 e Study 2 (AREDS2), for treatment of AMD and cataract.

14 95 million people worldwide are affected by cataract.

15 re associated with congenital or early-onset cataract.

16 et) and 15 control patients with age-related cataract.

17 crystallin mutant associated with congenital cataracts.

18 ogy in the management of severely subluxated cataracts.

19 CT) and Placido disk topography in eyes with cataracts.

20 thelial-mesenchymal transitions that lead to cataracts.

21 follow-up, we documented a total of 768 new cataracts.

22 etes, sensorineural deafness, and congenital cataracts.

23 genes in 27 Chinese families with congenital cataracts.

24 eligible cases, especially in eyes with soft cataracts.

25 ies, neurocognitive developmental delay, and cataracts.

26 s and may prevent progression of early-stage cataracts.

27 requency of genes responsible for congenital cataracts.

28 The most common complications were cataract (0.31/EY), epiretinal membrane (0.16/EY), and r

29 etinopathy (odds ratio 2.52 [1.48-3.73]) and cataract (1.21 [1.17-1.25]) were more common among women

30 e GK group had a higher overall incidence of cataracts (10.11% vs. 7.26%; crude hazard ratio [cHR], 1

31 n to 65.4 million]), the leading causes were cataract (12.6 million [3.4 million to 28.7 million]), u

32 tly reported complications of treatment were cataracts (12.1%) and dry eye (8.5%).

33 s were uncorrected refractive error (61.3%), cataract (13.2%), and age-related macular degeneration (

34 The leading causes of vision loss were cataract (19.7%), corneal scars (15.7%), refractive erro

35 lithotripsy; arthroscopy, carpal tunnel; or cataract; 2.02 million) in California's Ambulatory Servi

36 s were uncorrected refractive error (60.8%), cataract (20.1%), and diabetic retinopathy (5.2%).

37 , dry eyes (34%), posterior synechiae (34%), cataract (32%), and glaucoma (15%).

38 diagnosed soon after birth (5/5), congenital cataracts (4/5), and hypotonia (4/5).

39 .3 million [49.4 million to 202.1 million]), cataract (52.6 million [18.2 million to 109.6 million]),

40 tive patients (mean age 71 +/- 9 years) with cataract, a Pentacam HR (Oculus) was used to measure CAT

41 We included patients with first-time cataract aged >/=40 years between 1995 and 2015 and an e

42 ntraocular lenses, the combined treatment of cataract and astigmatism or presbyopia, or both, is poss

43 ary open-angle glaucoma (POAG) patients with cataract and nonglaucomatous cataract patients.

44 found but no specific causative mutation for cataract and ONHD.

45 e disease (GSD Ia), DiGeorge syndrome (DGS), cataract and optic nerve head drusen (ONHD).

46 ular pressure, cystoid macular oedema (CMO), cataract and posterior capsule opacification.

47 The American Society of Cataract and Refractive Surgery (ASCRS) and the American

48 y exposed to radiation-induced diseases like cataract and the stochastic risk of left-sided brain tum

49 Cataract and uncorrected refractive error combined contr

50 cally uncontrolled glaucoma who had previous cataract and/or glaucoma surgery.

51 crystallin have been implicated in autosomal cataracts and skeletal myopathies, including heart muscl

52 out visual impairment, glaucoma, significant cataract, and major eye diseases, were selected from the

53 titis C virus (HCV) infection to age-related cataract, and to assess whether liver damage mediates th

54 luded that EMT is involved in human diabetic cataract, and upregulation of miR-30a can repress EMT th

55 asia, keratitis, corneal neovascularization, cataracts, and calcification.

56 cular dystrophy syndrome with short stature, cataracts, and intellectual disability.

57 neonatal/infancy-onset diabetes, congenital cataracts, and sensorineural deafness.

58 ; (7) macula pucker/epiretinal membrane; (8) cataract; and (9) quality of life.

59 vivo studies and support the hypothesis that cataracts are an amyloid disease.

60 ry challenging in some cases, for congenital cataracts are clinically and genetically heterogeneous d

61 Cataracts are formed by the aggregation of crystallin pr

62 Variants in 54 cataract-associated genes were screened by targeted next

63 whether liver damage mediates the hepatitis-cataract association.

64 ST completely mediated the HBV infection-any cataract association.

65 We identified 206 931 cataract cases and the same number of matched controls.

66 Cataracts cause vision loss through the large-scale aggr

67 d, but there is little evidence that ex vivo cataracts contain amyloid.

68 icantly lower in the NAION group than in the cataract controls (16.6 +/- 14.0 pg/mL; P = .002).

69 ly higher in the NAION group compared to the cataract controls (52.2 +/- 20.8 pg/mL; P = .010) and th

70 ic neuropathy (NAION) and normal age-related cataract controls.

71 nt postoperatively visual outcomes following cataract, cornea, glaucoma, strabismus and oculoplastics

72 Cataract corneal opacities, refractive error and amblyop

73 The main factors related with cataract development were the number of uveitis flares p

74 ses (age-related macular degeneration [AMD], cataract, diabetic retinopathy [DR], and glaucoma) and t

75 including age-related macular degeneration, cataracts, diabetic retinopathy, glaucoma, and intraocul

76 ned all Cochrane reviews that addressed AMD, cataract, DR, and glaucoma; were published as of July 20

77 The time to the cataract event was calculated as the time between recrui

78 Five of 6 had surgeries such as vitrectomy, cataract extraction, or a procedure for glaucoma control

79 years, we found a slightly increased risk of cataract for long-term SSRI users (adjusted OR, 1.24; 95

80 Prevention and reversal of cataract formation could have a global impact.

81 ical agents like NACA may eventually prevent cataract formation in high-risk populations and may prev

82 eine amide (NACA) eye drops in reversing the cataract formation induced by sodium selenite in male Wi

83 Intraocular pressure (IOP) and cataract formation were determined as safety endpoints.

84 rders including ischemia/reperfusion injury, cataract formation, and neurodegenerative diseases such

85 hat lens epithelial cells undergo EMT during cataract formation, and regulation of microRNAs on genes

86 uggesting the involvement of EMT in diabetic cataract formation.

87 due to their significantly increased risk of cataract formation.

88 between 1995 and 2015 and an equal number of cataract-free controls matched on age, sex, general prac

89 Public awareness of four ocular diseases; cataract, glaucoma, diabetic retinopathy (DR) and dry ey

90 Awareness of cataract, glaucoma, DR and DED was reported by 31%, 38%,

91 %, and 30% reported, blindness, retinopathy, cataracts, glaucoma, and double vision respectively, as

92 enses and that this correlates strongly with cataract grade and age.

93 indicated that NACA was able to reverse the cataract grade.

94 ed group than in the sodium selenite-induced cataract group.

95 formation regarding their work histories and cataract histories.

96 A significantly increased risk of cataract (HR, 1.08; 95% confidence interval [CI]: 1.03,

97 Purpose To estimate the risk of cataract in a cohort of nuclear medicine (NM) radiologic

98 , a complete eye examination showed ONHD and cataract in both eyes.

99 mine the risk factors for the development of cataract in children with uveitis of any etiology.

100 Eyes treated for monocular cataract in infancy have axial growth similar to that of

101 The prevalence of cataract in our cohort was 44.2% and was highest among e

102 estimate hazard ratios (HRs) for the risk of cataract in radiologic technologists according to NM wor

103 min K1 was associated with a reduced risk of cataracts in an elderly Mediterranean population even af

104 y vitamin K1 intake and the risk of incident cataracts in an elderly Mediterranean population.

105 We tested patients born with dense cataracts in one or both eyes that blocked all patterned

106 ent rates or neurocognitive events, although cataract incidence appeared to be increased in the group

107 However, no difference in cataract incidence was observed between pooled alirocuma

108 Hazard ratios and 95% CIs for cataract incidence were estimated with a multivariable C

109 ed intraocular pressure leading to glaucoma; cataracts, including posterior capsule defects requiring

110 Similarly, the prevalence of diagnosed cataract increased by 35.7% (P = .02) from 7.1% in 2007

111 A cataract is a pathological condition characterized by th

112 n]), the number of patients blind because of cataract is anticipated to rise to 13.4 million (3.3 mil

113 Congenital cataract is both clinically diverse and genetically hete

114 In this study, we found that development of cataract is common among pediatric eyes with uveitis and

115 Cataract is the leading cause of blindness in developing

116 Congenital cataract is the most frequent inherited ocular disorder

117 in this age group, with a low prevalence of cataract (<22% for blindness and 14.1-15.9% for vision i

118 Selected cases of severely subluxated cataracts may be managed using femtosecond laser technol

119 on of vimentin and alpha-SMA in our diabetic cataract model in vitro.

120 Hepatobiliary adverse events (n = 7), cataracts (n = 4), deep vein thrombosis (n = 3), cerebra

121 ates of avascular necrosis, cytomegalovirus, cataracts, new-onset diabetes after transplant, and card

122 However, cataracts occurred in 57.4% of the 54 patients (n = 31)

123 strointestinal ulcers/bleeds, fractures, and cataracts (odds, 1.21-1.44 depending on the AE).

124 Cataract, one of the most frequent causes of blindness i

125 POAG patients was elevated compared with the cataract only subjects.

126 yopia and high corneal astigmatism underwent cataract operation with toric IOL implantation after pos

127 66 years of age or older undergoing isolated cataract operations in Ontario, Canada, between January

128 indicators included cataract surgery volume, cataract operations per surgeon, the proportion of direc

129 A total of 13 301 cataract operations with an AcrySof SN60WF implant and 5

130 The study evaluated 1 431 320 cataract operations.

131 in 57.4% of the 54 patients (n = 31) without cataract or implant at diagnosis.

132 ediates the effects of HBV infections on any cataract outcome, but the associations of HCV infection

133 short stature, intellectual disability, and cataracts, overlapping both the dystroglycanopathies and

134 This prospective study evaluated cataract patients from 13 counties in Sao Paulo State in

135 eneration sequencing in inherited congenital cataract patients provided significant diagnostic inform

136 ) patients with cataract and nonglaucomatous cataract patients.

137 Less than half of the individuals with cataract presented to the hospital for surgery.

138 Cataract progression did not occur.

139 ctrum in both emulsified post-surgical human cataract protein samples, as well as in whole lenses and

140 tched on age, sex, general practice, date of cataract recording (i.e., index date), and years of hist

141 specialist pediatric eye care facilities for cataract, refractive errors, glaucoma and rehabilitative

142 ly improve vision and decrease the burden of cataract-related loss of function.

143 r degeneration, and vision impairment due to cataract, resulting in 371 participants with myopia and

144 Preventable vision loss due to cataract (reversible with surgery) and refractive error

145 ptions) was not associated with an increased cataract risk (adjusted OR, 0.99; 95% CI, 0.94-1.03).

146 We aimed to assess cataract risk after exposure to SSRI or to other antidep

147 7), analyses revealed no association between cataract risk and specific radiation protection techniqu

148 SSRIs) has been associated with an increased cataract risk.

149 ental delays and/or intellectual disability, cataracts, severe epilepsy including infantile spasms, i

150 of human eye lenses with age-related nuclear cataract showed increasing concentration of fluorescent

151 ar mechanisms of this regulation in diabetic cataract still need to be investigated.

152 Cataract still remains the leading cause of blindness in

153 More experienced cataract surgeons did not benefit from simulator trainin

154 Eighteen cataract surgeons with different levels of experience.

155 All cataract surgeries (617 453) performed during the 29-mon

156 first eye and second eye phacoemulsification cataract surgeries at 5 veterans affairs centers in the

157 itals (38%) reported rates for uncomplicated cataract surgeries only.

158 nced a 59% average increase in the number of cataract surgeries per surgeon with 10 hospitals showing

159 A retrospective study of 330 cataract surgeries performed by resident physicians betw

160 s having performed fewer than 75 independent cataract surgeries showed significant improvements in th

161 ic examinations for first eye and second eye cataract surgeries.

162 dard outcomes (ICHOM) sets are available for cataract surgery (10 metrics) and macular degeneration (

163 common complication associated with routine cataract surgery (4.2% with PCME risk factors, 2.0% with

164 Of these, 18 (9.6%) had undergone cataract surgery (CS) during the year prior to developin

165 Femtosecond laser-assisted cataract surgery (FLACS) has gained in popularity due to

166 coma, reported success in glaucoma following cataract surgery (GFCS) and juvenile open-angle glaucoma

167 cation and sutureless, manual small-incision cataract surgery (M-SICS), as well as in patients with p

168 identified, clinical settings included post-cataract surgery (n = 6), post-penetrating keratoplasty

169 validated task-specific assessment tool for cataract surgery (Objective Structured Assessment of Cat

170 compared to placebo when used after routine cataract surgery (p = .0001).

171 seudophakic eyes or DMEK in combination with cataract surgery (triple-DMEK) between September 3, 2013

172 To determine whether cataract surgery accelerates disease progression in reti

173 To evaluate the barriers to cataract surgery after diagnosis and assess the postoper

174 gnificant cataract were randomly assigned to cataract surgery alone (control group, n = 31) or catara

175 well beyond levels achieved after first eye cataract surgery alone.

176 hospitals reported 22 different metrics for cataract surgery and 2 for macular degeneration, which s

177 nente Southern California patients underwent cataract surgery and 89 731 met inclusion criteria.

178 ant difference in RP progression between the cataract surgery and control groups (P = .23).

179 lectomy for presumed iris melanoma, combined cataract surgery and iris prosthesis placement, with or

180 ansducer on fifty-eight (58) eyes undergoing cataract surgery and the IOP was modulated manometricall

181 ield macular thickness) within 90 days after cataract surgery and the patients (%) with a best-correc

182 ion with intraocular lens implantation vs no cataract surgery at a single tertiary-level institution.

183 xial length (AL) from the time of unilateral cataract surgery at age 1 to 7 months to age 5 years, an

184 Cataract surgery at earlier stages by phacoemulsificatio

185 and fecal incontinence, and he had undergone cataract surgery at the age of 20 years.

186 oorer survival was associated with bilateral cataract surgery before enrollment compared with baselin

187 Patients undergoing cataract surgery between January 2007 and June 2014 were

188 All patients undergoing cataract surgery between July 1, 2014, and December 31,

189 The rate of cataract surgery did not change significantly during the

190 ation fills, visits to eye care clinics, and cataract surgery frequency.

191 a members who underwent noncomplex bilateral cataract surgery from January 1, 2013, through June 30,

192 al postoperative data were collected for the cataract surgery group, including preoperative and posto

193 By this time, cataract surgery has advanced to the point that Kelman's

194 ement of surgical technology and techniques, cataract surgery has evolved to small-incisional surgery

195 Second eye cataract surgery improves visual function and quality of

196 ntra-operative time, and anesthesia type for cataract surgery in a veteran population.

197 RD is estimated for the first 10 years after cataract surgery in children with no known ocular and sy

198 n promoting the accessibility and quality of cataract surgery in developing countries.

199 Cataract surgery in eyes with nanophthalmos is associate

200 k of posterior capsular rupture (PCR) during cataract surgery in eyes with previous intravitreal inje

201 mplantation of iris prosthesis combined with cataract surgery in eyes with previous iridocyclectomy f

202 s vehicle, based on clinical outcomes, after cataract surgery in patients with diabetes.

203 egrated analysis showing improved BCVA after cataract surgery in patients with diabetic retinopathy,

204 Our findings suggest that cataract surgery is a safe and effective means of improv

205 ost common vision-disrupting complication of cataract surgery is posterior capsule opacification (PCO

206 iating the past contributions of pioneers in cataract surgery is vital to understanding the developme

207 Furthermore, cataract surgery may be performed safely in eyes with fu

208 ts with postsurgical ME stratified into post-cataract surgery ME (PCSME) and post-other surgery ME (P

209 re the impact of first eye versus second eye cataract surgery on visual function and quality of life.

210 eassess the prevalence and incidence of post-cataract surgery optic neuropathy (PCSON) in the modern

211 devastating condition that can develop after cataract surgery or intraocular injection.

212 To review the history of cataract surgery over the past 100 years, and to offer p

213 te-onset endophthalmitis after clear corneal cataract surgery over the past 2 decades.

214 Cataract surgery patients who had a perioperative prescr

215 reality proficiency-based training on actual cataract surgery performance.

216 electronic databases were used to study all cataract surgery procedures undertaken between January 1

217 In total, 62 994 cataract surgery procedures were undertaken over the stu

218 Cataract surgery rates did not increase, which may indic

219 a simultaneous prophylactic sclerostomy with cataract surgery reduces complication rates, particularl

220 ional aspects of quality of life, second eye cataract surgery results in comparable improvement to fi

221 baseline EZ width, mode of inheritance, and cataract surgery status showed that there was no signifi

222 nge in a myopic direction from 1 month after cataract surgery to age 1.5 years was 0.35 diopters (D)/

223 ond laser intrastromal incisions made during cataract surgery to reduce corneal astigmatism.

224 acameral vancomycin use during an uneventful cataract surgery treated with early anti-VEGF treatment.

225 Key indicators included cataract surgery volume, cataract operations per surgeon

226 Median age at cataract surgery was 2.2 months (interquartile range [IQ

227 irty veteran patients were selected if their cataract surgery was performed between January and Septe

228 ctive study 63 patients undergoing binocular cataract surgery were divided into four groups for impla

229 The barriers to cataract surgery were older age, greater distance to the

230 New developments in cataract surgery will continue to improve the visual, an

231 Consecutive adult patients undergoing cataract surgery with bilateral implantation of the stud

232 act surgery alone (control group, n = 31) or cataract surgery with concomitant prophylactic sclerosto

233 ort the myopic shift at 5 years of age after cataract surgery with intraocular lens (IOL) implantatio

234 outcomes and complications during and after cataract surgery with or without prophylactic sclerostom

235 N: A 51-year-old female underwent uneventful cataract surgery with prophylactic intracameral vancomyc

236 d for age, sex, AMD severity, VA, history of cataract surgery, and assigned AREDS2 study treatment.

237 age-related macular degeneration, performed cataract surgery, and at least 10 intravitreal (excludin

238 s, including endogenous, postinjection, post-cataract surgery, and other anterior segment-related (eg

239 AREDS2, the presence of late AMD, bilateral cataract surgery, and VA less than 20/40 was associated

240 examined in South Indian patients requiring cataract surgery, PEX was associated with higher systoli

241 ecruitment and the date of the occurrence to cataract surgery, the time to the last visit of the foll

242 , followed up by routine phacoemulsification cataract surgery, was undertaken.

243 al, 12 eyes of 9 children developed RD after cataract surgery, with a median time of 70 months.

244 erature and author experiences pertaining to cataract surgery, with commentary and perspective.

245 on practice in children undergoing pediatric cataract surgery.

246 The most common clinical setting was post-cataract surgery.

247 for, retinal detachment (RD) after pediatric cataract surgery.

248 pect to achieve spectacle independance after cataract surgery.

249 CS) and delayed sequential (DSBCS) bilateral cataract surgery.

250 verall risk of RD was 5.5% at 10 years after cataract surgery.

251 s safe future combined pIOL explantation and cataract surgery.

252 an 40 years with or without PEX who required cataract surgery.

253 sults in comparable improvement to first eye cataract surgery.

254 scores comparing first eye versus second eye cataract surgery.

255 diagnosis of macular edema within 90 days of cataract surgery.

256 KA) between 0.75 and 2.5 diopters (D) during cataract surgery.

257 ular and long-term follow-up after pediatric cataract surgery.

258 ar edema is common after phacoemulsification cataract surgery.

259 that can occur after otherwise uncomplicated cataract surgery.

260 quantifying spectacle independence following cataract surgery.

261 e assessing spectacle independence following cataract surgery.

262 tion of PME incidence in patients undergoing cataract surgery; however, this relationship was not see

263 ncluding posterior capsule defects requiring cataract surgery; retinal tear; retinal detachment; reti

264 Cataract surgical outcomes for all operations performed

265 per surgeon, the proportion of direct paying cataract surgical patients, intervention program costs p

266 surgery (Objective Structured Assessment of Cataract Surgical Skill).

267 Clinically relevant cataract surgical skills can be improved by proficiency-

268 Cataract surgical training on a virtual reality simulato

269 ulted in proportionally similar increases in cataract surgical volume and productivity across diverse

270 9% average increase (range: -63% to 690%) in cataract surgical volume over baseline with 12 hospitals

271 ietary vitamin K1 intake had a lower risk of cataracts than those in the lowest tertile (hazard ratio

272 gio) studies had a higher risk of developing cataracts than those who did not (10.82% vs. 6.64%; cHR,

273 glaucoma patients with visually significant cataract that had phacoemulsification combined with trab

274 SMA and vimentin was upregulated in diabetic cataract tissues and the in vitro model, suggesting the

275 R-30a was markedly downregulated in diabetic cataract tissues.

276 million (51.0 million to 225.3 million), by cataract to 57.1 million (17.9 million to 124.1 million)

277 m shift from expensive surgical treatment of cataracts to relatively inexpensive prevention of vision

278 Of the 72 eyes with subluxated cataracts undergoing surgery during the study period, 47

279 The overall incidence of newly diagnosed cataract was 0.09 per eye-year, with an estimated 69% to

280 Cataract was diagnosed in the community by a mobile opht

281 26 patients (52%), progression or new-onset cataract was noted in 22 patients (44%), neovascular gla

282 Conclusion An increased risk of cataract was observed among U.S. radiologic technologist

283 time of presentation and the first instance cataract was recorded or findings at final follow-up.

284 In a propensity score analysis, the rate of cataracts was higher in patients with LDL-C <25 mg/dl (2

285 se family with autosomal dominant congenital cataracts, we recruited family members who underwent com

286 nships of HCV infection with nuclear and any cataract were formed only by their direct effects, not b

287 Risks of cataract were increased in the group who had performed a

288 ations of HCV infection with nuclear and any cataract were not mediated by high AST or ALT.

289 kia Treatment Study (IATS) with a unilateral cataract were randomized to IOL implantation with an ini

290 yes of 60 patients with visually significant cataract were randomly assigned to cataract surgery alon

291 Cataracts were evaluated at the end of week 2 (postpartu

292 -eight eyes from seventy-eight patients with cataracts were evaluated.

293 mean follow-up, 7(1/2) years), 7137 incident cataracts were reported.

294 ) (for DR) to 27 of 29 outcomes (93.1%) (for cataract), were also reported in the trials.

295 ontribute to both congenital and age related cataract when mutated, the extended promoter region of E

296 ulated over a lifetime, leads to age-related cataract, whereas inherited mutations are associated wit

297 n loss were uncorrected refractive error and cataract, which are readily treatable.

298 Six hundred patients were diagnosed with cataract with a mean age of 68.8+/-10.3 years and 374 (6

299 Odds ratios (ORs) for nuclear and any cataract with HBV infection were 1.09 [95% confidence in

300 an estimated 69% to develop uveitis-related cataract with time.