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   1 e been described, some of which are host and cell specific.                                          
  
     3 e found that the increase in Treg cells in T cell-specific A20-deficient mice was already observed in
     4 eficient mice fed a high-cholesterol diet, T cell-specific ABCG1 deficiency protected against atheros
  
  
  
  
     9  Akt3/+S472 in triple-negative breast cancer cells, specific ablation of Akt3/-S472 enhanced, whereas
    10 ly, we have shown that villin, an epithelial cell-specific actin-binding protein functions as an anti
  
  
  
    14 city of the kinesin-2 OSM-3/KIF17, whereas a cell-specific alpha-tubulin isotype regulates ciliary ul
  
  
  
  
    19 ether, this provides proof-of-concept that a cell-specific and region-specific gene expression approa
  
    21 ational approach for identifying effectively cell-specific and stimulation-specific promoter and enha
    22 gulates mitochondrial function; however, the cell-specific and temporal role of DRP1 in AKI in vivo i
  
    24 unohistochemically by antibodies that target cell-specific antigens in the cytosol or plasma membrane
  
  
  
  
    29 ll surface glycan by taking advantage of the cell-specific aptamer, and the lectin-functionalized gol
    30 tosterone (DHT)-induced PCOS with global and cell-specific AR-resistant (ARKO) mice to investigate th
  
    32 Thus, our study defines a proviral role of B cell-specific ATM expression during chronic gammaherpesv
    33  gammaherpesvirus tropism for B-1 B cells, B cell-specific ATM expression was necessary to support vi
    34 In summary, we identified a novel role for B cell-specific, BAFF-dependent transmembrane activator an
    35  the cost of high technical noise, including cell-specific biases in capture efficiency and library g
  
  
    38 l reprogramming by introducing individual TS cell-specific 'CAG' factors (Cdx2, Arid3a and Gata3), we
    39 Cardiac function significantly declined in T-cell-specific CD4-Cre(+/)(-)CD73(flox/flox) mice identic
  
    41 d a model of specific antibody deficiency, B cell-specific CD79a-Cre x XBP1 (X-box binding protein-1)
    42    Nectin-like 4 (NECL4, CADM4) is a Schwann cell-specific cell adhesion molecule that promotes axo-g
    43 ional variants that precisely co-locate with cell-specific chromatin domains and pancreatic islet enh
    44 -specific control module governed by a renal cell-specific chromatin structure located distal to Cyp2
    45 hment of neuronal fate with the formation of cell-specific ciliary structures in Caenorhabditis elega
    46 od was applied to the quantification of four cell-specific cluster of differentiation (CD) proteins u
    47 A library screening, we identified an immune cell-specific, co-stimulatory receptor B7.2 (CD86) as a 
  
  
    50  cells (DCs) from female mice with dendritic cell-specific conditional knockout of Prdm1 (CKO mice) a
  
  
    53 his research question, we have generated a T cell-specific Coronin 1a knock-out mouse (Coro1a(fl/fl) 
    54  RPE cells, we used two different mature RPE cell-specific Cre recombinase drivers to inactivate eith
    55 or neuron apoptosis, which can be rescued by cell-specific CRE-mediated expression of wild-type FUS w
    56  concentrations in the blood of sensitized T cell-specific Cyp27b1-KO mice support a lymphocyte-drive
  
  
  
  
  
  
  
  
  
    66 nticancer functions in vivo, and mice with T cell-specific deletion of Atg5 have reduced tumour outgr
    67 and regulatory (Treg) cells, and mice with T cell-specific deletion of Blimp1 (Blimp1CKO mice) sponta
  
  
    70 nesulfonic acid to control mice, mice with T-cell-specific deletion of GATA3, and mice with deletion 
  
    72 on of G-protein receptor kinase 3 (GRK3) nor cell-specific deletion of GRK3/arrestin-dependent p38alp
    73  we created mice harboring liver parenchymal cell-specific deletion of HOIP (Hoip(Deltahep) mice) by 
    74 rt here that mice with embryonic neural stem-cell-specific deletion of Llgl1 (Nestin-Cre/Llgl1(fl/fl)
    75 ucosal damage, we engineered mice carrying a cell-specific deletion of Nod2 in villin and Lyz2-expres
    76     Using mice with an intestinal epithelial cell-specific deletion of PPARdelta, we show that intest
    77 In addition, we studied AAI in mice with a T cell-specific deletion of recombination signal-binding p
  
  
  
    81  mice with a cardiomyocyte- or smooth muscle cell-specific deletion of the BK (CMBK or SMBK knockouts
    82 stigation of mice with intestinal epithelial cell-specific deletion of the p38alpha gene, we find tha
    83 equired for the acquisition of the dendritic-cell-specific demethylation and expression signature, fo
  
    85 r genotype; however, PG shows photosynthetic cell-specific differential localization depending on the
  
  
  
  
    90 xpanded minor clones and obtained epithelial cell-specific DNA/RNA for quantitative NGS analysis.    
  
    92 pirical Bayes approach to reliably model the cell-specific dropout rates and amplification bias by us
    93 estigated associations in this study between cell-specific dynamic signaling pathways and drug sensit
  
  
    96 ingly, mice with gastrointestinal epithelial cell-specific Egfr deletion demonstrated no differences 
    97 tion-induced cytidine deaminase (AID) is a B-cell-specific enzyme that targets immunoglobulin genes t
  
  
  
  
  
   103 ranscripts were validated by qPCR to confirm cell specific expression in microdissected tissues, as w
  
  
   106 its primary islet cell counterpart including cell-specific expression of beta (e.g., Pdx1) and alpha 
  
   108 ration of transgenic mice with smooth muscle cell-specific expression of either USP20 or its catalyti
  
   110 he first in vivo genetic evidence of sensory cell-specific expression of this unusual co-receptor and
  
  
  
  
  
   116 mproved vascular permeability of endothelial cell-specific Fli1-knockout mice by increasing the expre
   117 flammatory components of SSc and endothelial cell-specific Fli1-knockout mice recapitulating SSc vasc
   118 CR transgenic model of GVHD, wherein TS1 CD4 cells specific for a model minor histocompatibility Ag (
   119 TRAPeS with transcriptome analysis of CD8+ T cells specific for a single epitope from Yellow Fever Vi
   120 aive B cells was mirrored in a population of cells specific for an Ag to which these individuals were
   121 ence of ACPAs in the absence of detectable T cells specific for citrullinated antigens: ACPAs could a
   122 y HSV-specific CD8 T cells compared to CD8 T cells specific for control viruses, Epstein-Barr virus (
   123 & Microbe, Moguche et al. (2017) show that T cells specific for different immunodominant vaccine anti
  
   125     In blood samples from controls, CD4(+) T cells specific for FlaX, A4-fla2, or YidX had a T-helper
  
  
  
   129 leukemic effects can be delivered by donor T cells specific for particular minor histocompatibility (
  
  
   132 y of these mice to expand epitope-specific T cells specific for the model antigen ovalbumin expressed
  
   134 1 phenotype; a larger proportion of CD4(+) T cells specific for these proteins in patients with CD ha
  
  
   137 s the sole iron exporter in mammals, but its cell-specific function and regulation are still elusive.
  
  
  
   141 nhancers are regulatory elements that govern cell-specific functions and harbor disease-associated se
   142 uolation along the endosomal system, but the cell-specific functions of PIKfyve in vivo remain unclea
  
  
   145 ated by retinoic acid gene 8 (Stra8), a germ cell-specific gene activated during meiotic commitment. 
  
   147  mouse is commonly used for conditional hair cell-specific gene deletion/reporter gene activation in 
  
  
  
  
   152 age differentiation with curated phenotypes, cell-specific gene functions and a multiscale model.    
   153 s) and associated with highly expressed germ cell-specific genes and histone retention in mature sper
  
   155 ze the transcription factor STAT5 to control cell-specific genes at a larger scale than universal gen
  
  
   158 tly regulate the expression of multiple germ cell-specific genes, including Asz1 In addition, conditi
   159 ial expression analysis uncovered new immune-cell-specific genes, including novel immunoglobulin-like
  
  
  
   163  was attenuated in islets isolated from beta-cell-specific Ghsr knockout MIP-Cre/ERT;Ghsr(f/f) mice. 
  
  
  
   167 y, deletion of endothelial (but not myeloid) cell-specific HIF1alpha doubled pulmonary fibrin deposit
   168 eration during repair was attenuated in ATII cell-specific HIF1alpha knockout (SftpcCreERT2(+/-);HIF1
  
  
  
  
  
  
   175 avenous infusion, for studies in either beta-cell specific insulin receptor knock-out (betaIRKO) or c
   176 e receptors 1 and 2, dectin 1, and dendritic cell-specific intercellular adhesion molecule 3-grabbing
  
   178 tin occupancy at sites in the Igh locus is B cell specific, is correlated with histone H4 lysine 20 m
   179  a focus on VE-cadherin, a major endothelial cell-specific junctional protein that controls vascular 
  
   181 P on beta-cell function by the use of a beta-cell-specific knockout of the ANP receptor with guanylat
  
   183 stochemical staining revealed stronger tumor cell-specific labeling for C3 and CFB in invasive cSCCs 
  
   185      In this study, we generated endothelial cell-specific LKB1-knockout (LKB1(endo-/-)) mice by cros
  
  
  
  
  
   191 KO mice had decreased expression of the beta-cell-specific markers pdx1, glut2, mafA, and nkx6.1 and 
   192 growth parameters by analyzing expression of cell-specific markers revealed that the explant system m
  
   194 syndromes of DNA repair deficiency or immune cell-specific maturation or functional defects that sugg
  
  
   197 owever, it is not known whether there are ES cell-specific mechanisms regulating mitotic fidelity.   
   198 ce lifetime imaging microscopy (FLIM) to map cell-specific metabolic signatures in the kidneys of liv
  
  
  
  
  
   204 Cre, or Cdh5-CreERT2 driver lines to develop cell-specific models of Nox2 perturbation to investigate
  
  
   207  within the SVZ/RMS/OB system resulting in a cell-specific mosaic, suggesting complex EphA4 signaling
  
  
  
   211  Abe et al. (2017) identify NLRP14 as a germ-cell-specific negative regulator of DNA sensing that may
  
  
   214 were monitored in wild-type (WT) and myeloid cell-specific Nrp1 knockout (Nrp1(myel-KO)) mice fed an 
  
   216 o address this problem, we generated myeloid cell-specific Nrp1-knockout (Nrp1(myel-KO)) mice and app
   217 -targeted electrophysiological recording and cell-specific optogenetic manipulation in both anestheti
  
   219 have demonstrated that, although mice with T cell-specific overexpression of miR-27 harbor dysregulat
   220  vivo, vascular smooth muscle cell/mesangial cell-specific overexpression of Nox5 in a mouse model of
  
   222 ouse colon tissues and intestinal epithelial cell-specific p38gamma knockout (KO) attenuates colitis 
  
   224 Collectively, these findings unveil distinct cell-specific patterns of E-selectin ligand expression a
  
   226 uced with the tamoxifen-inducible, satellite cell-specific Pax7(CreER) system in postnatal satellite 
  
  
   229 tion of either Hif1a or Hif2a in endothelial cell-specific Phd2 mutants demonstrated that the develop
   230 proteome for normal IE function, providing a cell-specific pool of candidates for novel, important HC
   231 e the reads aligned to this gene to estimate cell-specific preferences for splicing, mutation load, o
  
  
   234 ressing S-della under the control of a guard-cell-specific promoter was sufficient to increase stomat
  
   236 mmon upregulation of marginal zone B- and B1-cell-specific protein (MZB1), the expression of which id
  
   238 reverse-phase protein arrays, the lymphocyte cell-specific protein-tyrosine kinase (LCK) as aberrantl
  
   240 plications after hearing onset, we show that cell-specific purinergic modulation follows a precise to
  
  
   243 le (SLAM) family of homotypic haematopoietic cell-specific receptors, we determined that phagocytosis
   244   We used chemogenetics to extend D1-/D2-MSN cell specific regulation to cue-reinstated cocaine seeki
  
   246 er Cdx2 regulatory elements including a stem-cell specific regulatory sequence and an element that dr
   247  different populations, gene expression, and cell-specific regulatory annotation can be effectively i
   248  data further indicate that ATAC-seq detects cell-specific regulatory elements for cell types compris
   249 t NOTCH1 transactivates MYC via binding to B-cell-specific regulatory elements, thus implicating this
  
  
  
   253  identify clock-relevant phosphatases, clock-cell-specific RNAi knockdowns ofDrosophilaphosphatases w
   254  system, renal, and vascular levels, but the cell-specific role of Nox2 in BP regulation is unknown. 
  
  
   257 he aptitude to triage stimuli depends on the cells' specific sensitivities to different chemoattracta
   258 e the scalability of SeqUnwinder to discover cell-specific sequence features from over one hundred th
  
  
   261 the simultaneous, temporally controlled, and cell-specific silencing of multiple genes or pathways.  
  
  
  
  
  
  
   268 aracterized the pathogenic potential of beta cell-specific T cells, we have limited mechanistic insig
   269 t sequence properties of multi-condition and cell-specific TF binding sites after controlling for une
  
   271 s has resulted in an unmet clinical need for cell-specific therapy in the treatment of FSGS and other
  
   273 ls or re-engineer natural materials to model cell-specific tissue-like 3D modules, which can seamless
   274 rrounding normal breast tissue to identify T cells specific to each, as well as their abundance in pe
   275 enic mouse system in which TCR-transgenic Th cells specific to hen egg lysozyme (HEL) are adoptively 
  
  
   278 of lymphocytes and proliferation of CD8(+) T cells specific to tumor-associated antigens, resulting i
   279 f effector memory CD8(+) T cells (CD8(+) TEM cells) specific to three epitopes derived from the HSV-1
   280 animals lacking distinct lung APC subsets or cell-specific Toll-like receptor (TLR) 4 signaling.     
   281 d myotube formation, we demonstrate that the cell-specific topology of syncytial nuclei is dependent 
   282 R targeting a peptide of the intracellular B cell-specific transcription factor BOB1 presented in the
  
   284 to asymmetric division and activation of the cell-specific transcription factor sigma(F), a hallmark 
  
   286 ell as indirect in vivo measurements such as cell-specific transcriptional analysis of ABA metabolic 
  
  
   289 latory elements such as enhancers coordinate cell-specific transcriptional programmes by engaging in 
   290  toolset for cell-type specific profiling of cell-specific transcriptomes derived from complex biolog
   291 timize parameters of FCM algorithm for human cell-specific transcriptomic data and identify robust ge
  
  
  
   295 ns, advances in DNA sequencing indicate that cell-specific variants affect a number of phenotypes and
   296 dy VDR KO, T cell-specific VDR (T-VDR) KO, B cell-specific VDR (B-VDR) KO, and vitamin D deficient mi
  
  
  
  
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