ライフサイエンスコーパス: clear

1 e, but its mechanism is still not completely clear.

2 late immune activation or tolerance are less clear.

3 dies are produced in memory responses is not clear.

4 lation of cell contractility is not entirely clear.

5 at is, I/R, LR, and liver malignancy-is less clear.

6 ition of phenotypes during childhood is less clear.

7 e connection between FXR1 and disease is not clear.

8 coinfection with respiratory viruses is not clear.

9 ng patterns are precisely established is not clear.

10 d regulate TGF-beta family ligands, are less clear.

11 heir origin and characteristics are not very clear.

12 regulated at the translational level is less clear.

13 sound symbolism are not, as yet, altogether clear.

14 nic, yet their underlying mechanisms are not clear.

15 pite increasing temperatures is not entirely clear.

16 of range shifts in riverine systems is less clear.

17 nterplay between these two mechanisms is not clear.

18 ria molecular interactions in nature are not clear.

19 isms for these associations are not entirely clear.

20 net loss of hydride, via steps that are not clear.

21 gression, and end-stage renal disease is not clear.

22 ural rationale for these observations is not clear.

23 However, the mechanisms are still not clear.

24 following ischemic insult are presently not clear.

25 tion is linked to polarity disruption is not clear.

26 The reasons for this are not clear.

27 function of these distinct processes are not clear.

28 , hereafter mexicana) to modern maize is not clear.

29 the effects of p53 on LMP1 expression is not clear.

30 own, whereas the pathogenesis of ONHD is not clear.

31 The role of mutations in GP and NP is not clear.

32 ; however, the impact of nonheavy use is not clear.

33 isms by which RAS proteins function are less clear.

34 nificance of INS-membrane interaction is not clear.

35 ing B cell autoimmune activation remain less clear.

36 on elongation speed in animal systems is not clear.

37 the regulation of this process is not fully clear.

38 m pathological aggregates if not effectively cleared.

39 olar concentrations in vitro, have aggregate-clearing activity in a cellular model of Huntington's di

40 A clear advantage of the sparse labeling approach is demon

41 Such bioelectrochemical systems have a clear advantage over more conventional microbial fuel ce

42 f 237 patients at screening, and there was a clear age gradient.

43 The results showed that clear AJ production can be achieved by the clarification

44 Ethyl cinnamate rapidly cleared all tested organs, including calcified bone, but

45 using the appropriate temperature for tissue clearing, all of which contributed to the superiority of

46 between pathogen and mutualist fungi become clear, although the outcomes are often opposite in effec

47 results suggest a distributed code, with no clear anatomical distinctions between auditory cortical

48 ety modulates M- and P-pathway processing of clear and ambiguous threat cues.

49 nefit, but only a subset of patients exhibit clear and durable responses, suggesting that other mecha

50 derwater grasses worldwide, we demonstrate a clear and rapidly emerging interaction with climate chan

51 Here, we use optical tissue clearing and a TAM-targeting injectable fluorescent nano

52 ween 2002 and 2005 on contemporaneous forest clearing and disturbance.

53 there is a high-affinity interaction is now clear, and its molecular basis is being unraveled, while

54 es are decoded to produce perception is less clear, and most models assume that decoding follows the

55 A clear answer hinges on observation of hallmarks of a rev

56 rmance of 4 PD-L1 platforms, including 2 FDA-cleared assays, 1 test for investigational use only, and

57 There was no clear association between low- or high-fat dairy intake

58 We found a clear association between sperm concentration below 15 m

59 Moreover, we observed a clear association of Gene 33 with histone H2AX and that

60 Fat-fed mice showed clear attenuation of ventilator-induced lung injury in t

61 tails of the injury burden in LMICs are less clear because of the scarcity of data and population-bas

62 The relevance of UMOD for CKD is clear, because the encoded protein, uromodulin (Tamm-Hor

63 However, when the intentions are clear beforehand, the proposers can emerge by themselves

64 cinogenesis hypothesis are well founded with clear biological relevance, and therefore, the premise w

65 The present study demonstrated a clear birth-cohort pattern of H. pylori infection in the

66 rdered-subset expectation maximization and Q.Clear (block-sequential regularized expectation maximiza

67 and vaccinia virus, where the pathogens are cleared, but it becomes a more complex issue in the cont

68 eins of the outer mitochondrial membrane are cleared by a newly identified quality control pathway in

69 , and pathological forms of TDP-43 typically cleared by autophagy accumulate more rapidly in PGRN-def

70 s, billions of cells die and must be swiftly cleared by phagocytes.

71 chanisms whereby Streptococcus pneumoniae is cleared by the spleen.

72 ria gonorrhoeae, but no commercial tests are cleared by the U.S. Food and Drug Administration for use

73 A clear candidate for this input is the head direction cel

74 Microglia lose their amyloid-beta-clearing capabilities with age and as AD progresses.

75 ltiple surveys: 71% remained noncarriers, 8% cleared carriage, 15% remained carriers, and 7% acquired

76 One clear case is saccadic suppression, the reduced visibili

77 Here, we show a clear causal relationship between the freeze-concentrati

78 to enteric pathogens, but capable of rapidly clearing causative and coinfecting pathogens.

79 Histopathological diagnosis was renal clear cell carinoma.

80 ogic fidelity, these models of papillary and clear cell RCC should be significant contributions to th

81 ognised as necessary for the pathogenesis of clear cell renal cancer (ccRCC); however, the molecular

82 ysregulation of chromatin-modifying genes in clear cell renal cell carcinoma (ccRCC) has been uncover

83 Some cancers, such as clear cell renal cell carcinoma (ccRCC), require exogeno

84 rface glycoprotein ubiquitously expressed in clear cell renal cell carcinoma (ccRCC).

85 six tandem BDs and is frequently mutated in clear cell renal cell carcinoma (ccRCC).

86 with treatment-naive progressive metastatic clear cell renal cell carcinoma were enrolled between Se

87 n an attempt to delay disease progression in clear cell renal cell carcinoma.

88 are the most prevalent molecular features of clear cell tumors.

89 The first clear change occurred just before 2000 CE, decades later

90 No clear change points were detected following EU-WID imple

91 roteasomal surveillance and shows subtle but clear changes in tertiary conformation.

92 REP 2139 clears circulating hepatitis B virus (HBV) surface antig

93 meanor, expertise, and efficiency and valued clear clinical communication, as well as words of reassu

94 Despite its clear clinical relevance, the neural circuitry governing

95 least in part, be credited to the lack of a clear conceptualisation of the term.

96 However, we also found a clear connection between the amplification and quantum d

97 This sensor system showed a clear correlation between the GA concentration and the r

98 We report clear correlations of the entropic and enthalpic contrib

99 facial features used to do so are not always clear-cut because they can be associated with opponent c

100 ar structure and the walls of the container, clear-cut experimental evidence for this prediction is l

101 refine neuronal connections, after injury to clear damaged neurons, or pathologically during disease.

102 e and elevation of Trem2, both necessary for clearing damaged myelin, were markedly reduced in GALC +

103 with local bacterial communities sampled on clear days, all collected at a single location: Rehovot,

104 es, localizes to claustral cells, enabling a clear delineation of claustrum.

105 We show a clear dependence of melanoma cell-cell adhesion on pHe a

106 ent genetic variants, in individuals without clear diagnosis of hematological malignancies.

107 The IHC assay has clear diagnostic potential to identify patients with a C

108 SID showed clear differences among S. cerevisiae populations in gra

109 ecognized multiple compounds, they exhibited clear differences in structure-binding characteristics.

110 abolites revealed significant modulation and clear differentiation in resistant and susceptible acces

111 Our predictions show that a clear distinction between unicellular and multicellular

112 ncreasingly smeared together, so measuring a clear distinction between where the glass ends and where

113 of the tree and provide for the first time a clear distinction of stem and crown Cervidae.

114 P deficiency include a decreased capacity to clear dying cells and the establishment of a lupus-like

115 e medical countermeasures may not completely clear EBOV infection.

116 Mechanistically, while they have no clear effect on kinase activity, L290P/V mutations enhan

117 However, a clear effect was observed on force relaxation: myofibril

118 These results demonstrate clear effects of seasonality, spatial structure, and tra

119 A clear elucidation of structural feature of whole lignin

120 comparable to these earliest ones, but show clear emergence of diverse traits, including increased c

121 e receptor C-type 1 (MR), which functions to clear endogenous mannosylated proteins, a principle used

122 These differences were clear even though Usp14 is present on only a minor fract

123 er the experimental conditions, and provides clear evidence for hydrogen atom tunneling in the H-isot

124 icularly bisphosphonates, and the absence of clear evidence in support of their long-term efficacy is

125 on of data from the subpolar Atlantic Ocean, clear evidence of a marked pre-bloom silicate decline of

126 erpendicular to the channels, thus providing clear evidence of connectivity.

127 fact, none of the available drugs has shown clear evidence of disease-modifying activity, even if so

128 The RBS compositional analysis gives clear evidence of Fe and Ru vacancies to an extent that

129 No clear evidence of Fukushima-derived (236)U and Pu isotop

130 eated with gammaretroviral vectors and found clear evidence of genotoxicity, indicated by numerous co

131 erogeneity in exposure and outcome measures, clear evidence shows that the burden of behavioural risk

132 This trial provides no clear evidence that Care Co-ordinators (largely nursing

133 To date, however, there has been no clear evidence that odours encode population-level infor

134 ng malnutrition; however, there is a lack of clear evidence to support its implementation.

135 Collectively, our results provide a clear example of how site-specific PARylation drives bio

136 We suggest that these data provide a clear example of parallel evolution in a complex neurome

137 t observe stroke rates that would indicate a clear expected net clinical benefit for anticoagulating

138 A clear feature is a persistent southward shift of the ITC

139 Mycoplasma genitalium in male urethritis is clear, fewer studies have been conducted among women to

140 All images led to a clear final diagnosis.

141 % (at +/-20%) of TEX levels while it is less clear for xylenes at some locations.

142 It is clear from this review that there is no single or privil

143 n tumor (2 h after injection) and is rapidly cleared from all other organs except kidneys and liver.

144 d a dissociation constant (HSA) of 11.2 muM, cleared from the blood over the course of 48 h and showe

145 2-microglobulin/ Nb24 pre-formed complex, is cleared from the circulation at the same rate as the unc

146 We showed that asparaginase is rapidly cleared from the serum by liver-, spleen-, and bone marr

147 We hypothesized that there should be clear geographically coherent genetic structuring within

148 Optical tissue clearing has revolutionized researchers' ability to perf

149 rated with diverse pheromones, but it is not clear how ants perceive these social signals.

150 is known for more than a century, it is not clear how cells perceive the external EF.

151 curs during diabetes development, it was not clear how human islets of T2D patients would respond to

152 be important to maintain cohesion, it is not clear how many neighbors each individual can simultaneou

153 c cause has long been known, it is still not clear how mutations at this locus produce this array of

154 It is not clear how stem and proliferating cells cope with accumul

155 However, it is not clear how the activation of Gi-coupled GPCRs at the LE o

156 BACKGROUND & AIMS: It is not clear how the complex interactions between diet and the

157 Consequently, it is less clear how the unbound, sensing riboswitch refolds into t

158 However, it is not yet clear how these two important components of the chaperon

159 arget for neutralizing antibodies, it is not clear how these viruses avoid cross-neutralization.

160 he stable flipped-out complex, but it is not clear how this complex differs from nonspecific complexe

161 At present, it is not clear how twitching motility emerges from these initial

162 It is not clear how using partial-mouth periodontal examination (P

163 modulates channel gating, although it is not clear how.

164 It is not clear, however, how alpha oscillations are controlled an

165 It is less clear, however, how redox reactions would contribute to

166 It is less clear, however, if chronic pain can also induce a genera

167 It is not yet clear, however, whether this association results from ca

168 These records reveal a clear HS11 freshwater signal, which attenuated toward th

169 of IgE-derived drugs in clinical oncology is clear if the antitumor activity of MOv18 IgE in these pr

170 lease Rrp6 and recruits Mtr4, but it is less clear if these cofactors work together.

171 Currently, it is not clear if these differences are due to cryptic wSuz polym

172 rate in response to the 3D matrix, it is not clear if they can switch between high- and low-pressure

173 cited in a semiconductor, it is a priori not clear if they form a plasma of unbound fermionic particl

174 ontribute to the rescue of cooperation, in a clear illustration of how ecology and evolution can infl

175 grown exponentially across dentistry with a clear impact in implant dentistry.

176 ver, we report that treatment efficacy has a clear impact on the population dynamics: sufficient drug

177 ological strategy for trans-repression, with clear implications for breast cancer and other diseases.

178 Despite the clear importance of astrocytes for the establishment and

179 Clear improvements in measured detective quantum efficie

180 Clear increases in Hg and Hg/TOC are observed at the end

181 A clear indication of nonlinearity was seen for the relati

182 Women who cleared infection had significantly lower tryptophan lev

183 ozen product) are lower than 1, indicating a clear influence of the stages of the freezing process, e

184 Alpha-band oscillations also carried clear information about the location of the stimulus, bu

185 To date there is no clear information on the role of VEGF-A in IPF.

186 ortant immunoregulatory functions and are of clear interest for cancer immunotherapy.

187 pecies (ROS) during the day and is unable to clear it during the night.

188 arameters for the experimental use of VOR to clear latent infection.

189 omplexity.SIGNIFICANCE STATEMENT Humans have clear limits in their ability to solve complex reasoning

190 This establishes a clear link between inner membrane architecture and funct

191 ymic epithelial cells (TECs) is evidenced by clear links between their dysfunction and multiple disea

192 lerant mycobacterial persisters, and rapidly cleared M. tuberculosis infection in vivo.

193 Although unsupported monolayers exhibited clear major and minor strain axes, they were not correla

194 This is a clear manifestation of the transition from incoherent-ph

195 ter initial lumpectomy to obtain more widely clear margins is common and may lead to mastectomy.

196 the mean (SD) area of surgical excision with clear margins was 7.74 (5.28) cm2.

197 There was no clear mechanism for this association, although it is con

198 However, a clear mechanistic link between TMAO and such diseases is

199 Optical clearing methods can facilitate deep optical imaging in

200 However, CD177(pos) neutrophils exhibit no clear migratory advantage in vivo, despite interruption

201 y flow cytometry (high-responder donors) are cleared more quickly from the circulation than those fro

202 Postmortem studies have identified clear morphological characteristics associated with plaq

203 by macroscopic techniques so far, there is a clear need for local-probe measurements.

204 As a result, there is a clear need to identify paleoclimate records extending in

205 e constitutive internalization property that clears negative regulators of the WNT-receptor complex f

206 y its lack of reproducibility, its lack of a clear normal value, and the fact that it is not specific

207 eatures within large tissue sections.Optical clearing of tissue has enabled optical imaging deeper in

208 When forest is fragmented, cut, thinned, cleared or otherwise altered in structure, local climate

209 Because mice do not have a clear ortholog of IFI16, this system is not suitable for

210 V has high sensitivity and specificity, with clear performance gains over the latest method.

211 g paired with emerging immunotherapeutics to clear persistently infected cells will soon allow measur

212 ts in two-dimensional materials will offer a clear picture of the defect physics involved to demonstr

213 tion during infection, IL-17A-deficient mice cleared Pneumocystis infection with kinetics similar to

214 Suicide remains a clear, present and increasing public health problem, des

215 by pharmaceutical companies are some of the clear reasons behind market failures and a poor pipeline

216 near correction, monovision produced both a clear reduction of the earliest visual evoked potential

217 n and productivity are inversely related, no clear relationship between density and productivity is o

218 We find no clear relationship between emission factors and aircraft

219 Moreover, there is a clear relationship between the change in magnitude of GA

220 A clear relationship between the work recoverable ratio an

221 lar, pathologic, and clinical features, with clear relevance for patient management.

222 13 weeks-the US Food and Drug Administration cleared response measure); a 30%, 50%, and 70% decrease

223 RNA-binding-defective mutants demonstrate clear separation of function by becoming DNA hypermutato

224 analysis of LC-MS/MS data, however, revealed clear separation of HTST-treated samples from untreated

225 vitelliform material accumulation leads to a clear separation of the outer retinal layers.

226 Clear separations between each two groups were obtained

227 In addition, this work provides a clear sign of sea level-driven glacial/interglacial osci

228 py was generally well tolerated, without any clear signal of any unexpected adverse effects.

229 stem with just one coupling path, which is a clear signature of constructive quantum interference.

230 n dynamics: sufficient drug pressure bears a clear signature of purifying selection leading to appare

231 The majority of melanomas emerge from clear skin without a precursor lesion, but it is unknown

232 Small, round clear spheres in vitreous on dilated biomicroscopic reti

233 -VlsE antigens became sufficiently potent to clear spirochetemia induced by DeltaVlsE and yet failed

234 ed Scnn1b-Tg(+) (FA-Tg(+)) mice successfully cleared spontaneous bacterial infections by PND22, the S

235 are distributed across boundaries and find a clear stepwise pattern.

236 immunity, providing greater capabilities to clear sublethal bacterial challenges, possibly at the co

237 purified Ydr109c and FGGY proteins showed a clear substrate preference of both kinases for d-ribulos

238 ng body of literature, there is a need for a clear summary of TBI neuroimmunology.

239 cation whether done with a clear temporal or clear superior wound, does not affect intraocular pressu

240 abeling of endothelial cells, a novel tissue-clearing technique, lightsheet microscopy, and automated

241 that phacoemulsification whether done with a clear temporal or clear superior wound, does not affect

242 It has recently become clear that alarmins play important roles as initiators a

243 ation in vertebrates, it has recently become clear that core components of the cGAS-STING pathway evo

244 It is clear that discretization, when implemented properly, ca

245 cations is beginning to take shape, but it's clear that in both coding and noncoding RNAs, dynamic mo

246 study of integrin biology, and it has become clear that integrin outside-in signaling is highly compl

247 e against oxidative stress, from which it is clear that RSSH are much more reactive to two-electron o

248 Although it is clear that Shigella requires N-WASP for this process, th

249 It is, however, becoming clear that significant pathology, such as microglial act

250 It is clear that the aberrant expression of miRNAs promotes tu

251 It is now clear that the capacity of cells to maintain proteostasi

252 The evidence is now clear that the environment is the single largest source

253 the chromosomal contact map, however, it is clear that the organization of the domains is not simple

254 It is clear that the use of CIDTs for enteric pathogen detecti

255 It is clear that these millennia of impacts need to be taken i

256 Importantly, MEK1 activity was necessary to clear the pluripotency protein Ventx2 at the onset of ga

257 bamazine, and albendazole) has been shown to clear the transmissible stage of the helminth completely

258 ystem to be tuned to the desired load and to clear the working memory of currently held items to make

259 his, we found that convalescent mice rapidly cleared the bacteria after reinfection.

260 und 23 also reversed physical disability and cleared the brain of T-cell infiltration in an EAE mouse

261 All patients cleared the virus while on therapy and 100% have achieve

262 persistent infection, immune-competent mice cleared the virus within 3 to 5 weeks.

263 Among those who cleared their first infection spontaneously, the likelih

264 stent warts than in those that spontaneously cleared their infection.

265 orship Care Guideline, published in 2016, is clear, thorough, clinically practical, and helpful, desp

266 tunement of the magnocellular (M) pathway to clear threat, and of the parvocellular (P) pathway to th

267 and spleen whereas (64)Cu-DA(IR800)-TOC was cleared through the kidneys.

268 luorescent signal was achieved by decreasing clearing time, adjusting the pH of the SDS solution, and

269 However, it is not clear to what extent misincorporation occurs in tissues,

270 Here the authors show that cells clear trailing chromatids from the cleavage site in a tw

271 ntirely on crystalline structures, yet now a clear trend is emerging, shifting the emphasis onto diso

272 he high molecular weight population showed a clear trend of reduced molecular weight with increasing

273 pha-motility." Mining genomic data reveals a clear trend: only organisms with both WASP and SCAR/WAVE

274 No clear trends were evident in the ratios of load estimate

275 Together, these data provide a clear, unbiased view of the full spectrum of genes regul

276 ruition in the last five years, generating a clear understanding of a complex cytokine-driven cellula

277 y in this aspect; however, there is still no clear understanding of electron transport, as reported v

278 A clear understanding of normal structural brain developme

279 h healthcare costs inherent in device use, a clear understanding of the clinical benefits relative to

280 A clear understanding of the immune cell populations regul

281 Clearing up these conceptual confusions is a necessary f

282 y-two of 93 pocapavir-treated subjects (56%) cleared virus in 2-18 days with no evidence of drug resi

283 However, it is not clear what molecular identification accuracy and how man

284 However, it is less clear whether C. hirsuta petal number varies in response

285 h ECRs regulate receptor function, it is not clear whether ECRs play a direct regulatory role in G-pr

286 gland development during puberty, it is not clear whether its overexpression alters normal mammary d

287 However, it is not clear whether neuronal activity may be specifically regu

288 mal models of atherosclerosis, it is not yet clear whether NK cells behave as protective or proathero

289 However, it is not yet clear whether schema-related integration neural mechanis

290 However, it is not clear whether the activity of central auditory neurons i

291 lf-generated sounds is well known, it is not clear whether the learned action-sound association modif

292 eins from infected to naive cells, it is not clear whether the viral genome is also transferred via t

293 egulators of memory formation, but it is not clear whether this function depends on HDAC enzymatic ac

294 perceived nutritional environment-it is not clear whether this process occurs in mammals.

295 en extensively characterized, but it is less clear whether this sequence-specific interaction is suff

296 n breast cancer and lymphomas, but it is not clear which additional Rb-positive cancers might benefit

297 een implicated in social behavior, it is not clear which neurons are relevant or how they contribute.

298 It is not clear why so many extracellular domains need to be evolv

299 exone resulted in flaring of symptoms, which cleared within 2 to 3 days on rechallenge with low-dose

300 total BPA-d16 peaked within 5 h and quickly cleared within 24 h.