ライフサイエンスコーパス: down-regulation

1 ex in NF-kappaB repression by attenuating GR down-regulation.

2 ferredoxin were early targets of transcript down-regulation.

3 es EfnA1 expression, and EfnA1 induces EphA2 down-regulation.

4 for CD4 and AP-2 recruitment as well as CD4 down-regulation.

5 nib-resistant HCC827 cells caused by miR-214 down-regulation.

6 in vitro and in vivo and affords maximal MYC down-regulation.

7 d revealed an unexpected role for IKK2 in GR down-regulation.

8 cells, and resistant to chemotherapy-induced down-regulation.

9 m responded to the cold by undergoing up- or down-regulation.

10 rescue of the protein from cyclin F-mediated down-regulation.

11 g, which is abrogated through MDA-9/Syntenin down-regulation.

12 xtensive gene networks, driving both up- and down-regulation.

13 f primary sclerosing cholangitis by miR-200b down-regulation.

14 C by a mechanism that does not rely on Mcl-1 down-regulation.

15 PTEN down-regulation after hepatectomy promotes the burning o

16 es in a repressive conformation, whereas its down-regulation allows the progression through the myoge

17 Finally, we show that USP36 down-regulation alters cell proliferation in human cance

18 hat tensile cell stress leads to rapid ACKR2 down-regulation and concurrent miR-146b up-regulation.

19 n receptor in CD4(+) T cells, allowing Thpok down-regulation and differentiation into DP IELs.

20 , siRNA-mediated IKK2 knockdown decreased GR down-regulation and increased GR expression.

21 Combined Grb14 down-regulation and insulin signaling blockade using pha

22 s (KFs), the causal association between CAV1 down-regulation and its aberrant responses to mechanical

23 Gene function was characterized by down-regulation and overexpression.

24 ion of CIITA is mainly responsible for CIITA down-regulation and subsequent antigen presentation.

25 essure-overloaded mouse hearts prevented its down-regulation and the consequent increase in MCU conte

26 -terminal cleavage participating in receptor down-regulation and, moreover, that the receptor is modi

27 Acrolein also caused the down-regulation and/or redistribution of three represent

28 Its overexpression and down-regulation antagonistically affect the alpha Aurora

29 Trim32 down-regulation attenuated the loss of desmin and myofib

30 GSK-3beta down-regulation blocked induction of MesoMT.

31 ates adipogenic differentiation and that its down-regulation by miR-130 during DIO may contribute to

32 PhABCG1 down-regulation by RNA interference results in decreased

33 L, CEACAM7, GATA2, HHEX, KLRG1, and OGN This down-regulation can be rescued by a small molecule inhib

34 Moreover, LGR4 down-regulation decreased in vitro migration and in vivo

35 1 in preadipocytes and that the magnitude of down-regulation depends on interactions between Sp1 and

36 es documented that receptor internalization, down-regulation, direct recycling, or Smad signaling wer

37 ssor of adipogenic differentiation since its down-regulation (DR) in both ex vivo bone marrow-derived

38 motes HIV-1 replication, suggesting that its down-regulation during HIV infection may be part of an a

39 More importantly, Ankrd26 down-regulation enhanced secretion of pro-inflammatory m

40 ly loss of RIN1 blocks surface AMPA receptor down-regulation evoked by chemically induced long-term d

41 whals displayed a paradoxical cardiovascular down-regulation (extreme bradycardia with heart rate </=

42 For occludin, down-regulation had no impact on wound healing in normal

43 ulated in different types of cancer, and its down-regulation impairs cell cycle progression.

44 with diseased cells, we only found a modest down regulation in prostanoid concentrations, whereas it

45 h showed consistent and reproducible twofold down-regulation in Bullies.

46 ively, these results suggest a role for CAV1 down-regulation in linking the aberrant responsiveness t

47 g growth factor deprivation and that miR-874 down-regulation in osteosarcomas leads to CCNE1 up-regul

48 e only IBD risk-associated gene with >5-fold down-regulation in the IFNG-secreting subset.

49 regulator of mitochondrial function, and its down-regulation in the liver may contribute to obesity-i

50 Furthermore, SHP-2 down-regulation in vivo promoted LPS-induced neutrophil

51 NKCC1 as a novel target for Nedd4L-mediated down-regulation in vivo, which modulates ion and fluid t

52 The KRAS down-regulation induces apoptosis together with a dramat

53 uced exon skipping resulted in specific Alk4 down-regulation, inhibition of MSTN activity, and increa

54 This down-regulation is accompanied by eviction of Ifh1p and

55 r, the precise mechanism of CIITA and MHC-II down-regulation is not well studied.

56 FAK down-regulation leads to aberrant ciliogenesis due to im

57 PTEN down-regulation may promote beta-oxidation through beta-

58 ) in pregnant mice leads to HB-EGF and COX-2 down-regulation near embryos and attenuates decidual rea

59 wever, it remains unknown to what extent top-down regulation occurs, or whether the relative importan

60 showed that, in cardiomyocytes, a reciprocal down-regulation occurs between beta1-adrenergic receptor

61 eral prefrontal cortex (dlPFC) subserves top-down regulation of attention and working memory abilitie

62 Down regulation of dStim, the endoplasmic reticular calc

63 the level of FLT3 RNA and protein and to the down regulation of FLT3-ITD signature genes, thus linkin

64 cell differentiation loss of HMGNs leads to down regulation of genes involved in neural differentiat

65 These data revealed a significant down regulation of genes known to regulate RNA processin

66 invasion and proliferation in GH3 cells via down regulation of Glut1 and MMP2 expression and inhibit

67 ing while loss of H19 lncRNA prevents normal down regulation of p53 activity and therefore results in

68 ransferred miRNAs were functional, causing a down regulation of specific target genes, including the

69 uction by Mtb within macrophages also caused down regulation of TNF-alpha production by the macrophag

70 e up-regulation of 124, 130, 126 and 162 and down-regulation of 138, 251, 314, 168 DEGs, respectively

71 d DPA decreased significantly along with the down-regulation of ABA biosynthesis genes, ABA2 and NCED

72 ition and innate inflammatory pathways, with down-regulation of adaptive responses.

73 (e.g. ubiquinones), we reveal a new path of down-regulation of AHAS activity involving inhibition by

74 Down-regulation of all genes encoding proteins involved

75 n a manner dependent on MDC1, BRCA1 and ATM, down-regulation of And-1 impairs end resection by reduci

76 and post-FR treatment, and observed a marked down-regulation of AnnexinA8 (AnxA8) in transdifferentia

77 ssing the specific ApoH interaction site, or down-regulation of ApoH expression in either hepatic cel

78 lation of metallochaperone-like genes or the down-regulation of aquaporins and metal transmembrane tr

79 Down-regulation of AsFAR expression by injection of doub

80 Activation of SnRK1 leads to the down-regulation of ATP-consuming biosynthetic processes

81 hows that SDHD-G12S and -H50R variants cause down-regulation of autophagy, demonstrating a role for S

82 Down-regulation of BCCIP reduces DSB repair and disrupts

83 ha-dependent manner, with concurrent up- and down-regulation of Bcl-2 and Bax, respectively, revealed

84 ation of Bax, cleaved caspases-3 and -9, and down-regulation of Bcl-2, MMP-2 and -9, NF-kappaB and Ik

85 suggest that miR-15a and miR-16 mediate the down-regulation of BMI1, which impedes DNA repair while

86 Whereas down-regulation of bta-miR-23a by its inhibitors increas

87 Our data suggest that, upon down-regulation of CAD1, coniferaldehyde is converted in

88 little effect on HR, potentially reflecting down-regulation of cardiac beta-adrenergic receptor func

89 ncogene-induced premature senescence through down-regulation of caveolin-1 expression to progress fro

90 promoter hypermethylation is associated with down-regulation of CCND1 regulatory genes in sporadic pa

91 The down-regulation of CCNE1 by miR-874 is independent of E2

92 Nef triggers rapid down-regulation of CD4 via the endocytic adaptor protein

93 Injection of wild-type Tregs prevented this down-regulation of CD62L.

94 Down-regulation of cell wall biosynthesis (via D-sedohep

95 Endocytic down-regulation of cell-surface proteins is a fundamenta

96 ZEB1, leading to induction of miR-183-5p and down-regulation of CHOP, and show that AGGF1 can effecti

97 L, encoded by Rv1198, is responsible for the down-regulation of CIITA/MHC-II by inducing H3K9me2/3.

98 formation, up-regulation of collagen I, and down-regulation of collagen III.

99 ely, our studies highlight the importance of down-regulation of COUP-TFII signaling to allow for the

100 Here, we show that down-regulation of CSE in hybrid poplar (Populus tremula

101 uantification (RQ) 1 vs. 2.33, P < 0.05] and down-regulation of Cyclin D1 (n = 7; RQ 1 vs. 0.61, P <

102 d the induction of mitochondrial biogenesis, down-regulation of diabetes-related genes, and increased

103 effects were demonstrated via mortality and down-regulation of Diap1 mRNA levels in M. domestica lar

104 This modulation is attributed to a profound down-regulation of digestive enzyme genes and trypsin ac

105 ail family of transcriptional repressors and down-regulation of Drosophila E-cadherin (DEcad) transcr

106 (PD) and eplin knockout cell lines exhibited down-regulation of E-cadherin and a reduction in alpha/b

107 y, stimulation with FPR2 ligands resulted in down-regulation of E-cadherin and up-regulation of vimen

108 spD itself did not result in transcriptional down-regulation of effector proteins.

109 Functional studies showed that specific down-regulation of either HIF1alpha or TWIST1 inhibited

110 Furthermore, we demonstrate that down-regulation of endogenous miR-181a and miR-30a level

111 eraction and is required for NOSTRIN-induced down-regulation of endothelial cell proteins.

112 Down-regulation of ErbB2 by CL-387,785 decreased the lev

113 Two hours of hypoxia caused significant down-regulation of extracellular matrix genes followed b

114 el of global H2Bub1 in mouse ES cells, while down-regulation of Fbxl19 reduces the level of H2Bub1.

115 ts2) protein was also evident by the up- and down-regulation of female-specific Ds-Yolk protein 1 (Ds

116 lation of the transferrin receptor (TfR) and down-regulation of ferritin, leading to an increase in i

117 uclear export for degradation and consequent down-regulation of FOXO3a-target autophagy-related gene

118 GATA, ROG) and that ZBTB32 is essential for down-regulation of GATA3 via ZPO2.

119 Here, we report a GBA1-dependent down-regulation of GBA2 activity in patients with Gauche

120 By using tetracycline-inducible down-regulation of gene expression and in vivo and in vi

121 ity, with cell fate changes driven by up- or down-regulation of gene expression.

122 In contrast, we observed a down-regulation of genes associated with neurogenesis an

123 Early down-regulation of genes associated with the extracellul

124 intricate process that includes a concerted down-regulation of genes encoding rRNA and ribosomal pro

125 ation of genes involved in cell survival and down-regulation of genes involved in apoptosis and chrom

126 ion in vivo or ex vivo is accompanied by the down-regulation of genes involved in embryonic developme

127 ident in all treatments, as indicated by the down-regulation of genes involved in metal homeostasis a

128 , exposure to both compounds resulted in the down-regulation of genes involved in stresses not direct

129 dditionally, Phf6(KO) cells show significant down-regulation of genes involved in the development and

130 lation of glycolytic genes and a concomitant down-regulation of genes required for oxidative phosphor

131 Although down-regulation of genes that promote the mature acinar

132 gest the possible role of caspase-3 mediated down-regulation of GIRK channel function and expression

133 tor) blocked PrP(C) internalization, whereas down-regulation of GIT2 and VPS28 increased PrP(C) inter

134 There was an unexplained rapid, transient down-regulation of glycolytic genes.

135 site to those of LTs, with up-regulation and down-regulation of gonadotrophin gene expression during

136 against Shiga toxin-1-induced cell death via down-regulation of GPP130, a cycling Golgi membrane prot

137 tly decreased PCa cell proliferation through down-regulation of GR and up-regulation of manganese sup

138 id evolution of tight regulatory control for down-regulation of growth and up-regulation of conidia p

139 The down-regulation of H2A ubiquitination by loss of functio

140 tion of IL-17A signaling was associated with down-regulation of hepatic Ccl2/Ccr2 messenger RNA expre

141 ildly hypothyroid mice develop NAFLD without down-regulation of hepatic TH signaling or decreased hep

142 Down-regulation of hepatocyte nuclear factor-4alpha expr

143 denocarcinoma, loss of Notch activation, and down-regulation of Hes1.

144 Finally, RNAi-mediated down-regulation of host autophagy protein 5 (ATG5) or au

145 Down-regulation of IGF-1 upon Cry deficiency correlates

146 ng M. smegmatis and mouse splenocytes led to down-regulation of IL-2, a key cytokine involved in T-ce

147 IL-1R (-/-) corneas also showed down-regulation of IL-6 and CXCL1 genes with and without

148 Down-regulation of immune response pathways, including n

149 Fear conditioning induced both up- and down-regulation of individual cells' CS-evoked responses

150 8-depleted tumors before involution revealed down-regulation of inflammatory response genes, pointing

151 de a molecular explanation for BCAP-mediated down-regulation of inflammatory signaling.

152 e expression profiling indicated substantial down-regulation of insulin-like growth factor binding pr

153 is an important regulator of metastasis and down-regulation of its activity is associated with incre

154 econdary wall formation through selective up/down-regulation of its downstream transcription factors

155 by CDK2 discharged its antitumor activity by down-regulation of its inhibitory role in cell migration

156 common carotid arteries, and siRNA-mediated down-regulation of its levels substantially attenuated B

157 relocation of YAP1 to the nucleus after the down-regulation of its phosphorylated state mediated by

158 e inactivation of the hormone and subsequent down-regulation of JA-dependent defenses.

159 This was accompanied by the down-regulation of key genes involved in meristem develo

160 In conclusion, down-regulation of KLF2 in the carotid body increases CB

161 nhibition with Dkk-1 prevented the P-induced down-regulation of Klotho.

162 PKC activation triggers down-regulation of Kv1.3 by inducing a clathrin-mediated

163 Also, we showed that IDH1 mutations caused down-regulation of leukocyte chemotaxis, resulting in re

164 o change in body weight, but correlated with down-regulation of lipolysis and lipogenic indices.

165 ed in the activation of cell-cycle genes and down-regulation of markers of terminal differentiation.

166 suggest that LPS-induced IL-10 promotes the down-regulation of MC surface FcepsilonRI expression and

167 Impaired MCUC function, resulting from down-regulation of MCU and up-regulation of an inhibitor

168 , these mutants failed to rescue Nef-induced down-regulation of MHC class I, suggesting a possible me

169 -coated vesicles (CCVs), and also facilitate down-regulation of MHC-I by HIV-1 Nef.

170 environment resulted in rapid and extensive down-regulation of microglia-specific genes that were in

171 Down-regulation of microRNA-200a expression in melanoma

172 The down-regulation of miR-101 occurred via the E26 transfor

173 marrow derived SSCs resulted in significant down-regulation of miR-146b.

174 d gene regulated through cell type-dependent down-regulation of miR-181a and miR-30a in innate sentin

175 -dependent phosphorylations, and conversely, down-regulation of miR-21 aggravated metformin's action

176 esults of the present study demonstrate that down-regulation of miR-214 may reverse acquired resistan

177 Our further studies show that down-regulation of miR-34a is caused by Enhancer of zest

178 Down-regulation of MIR34A was required for hypoxia-induc

179 essor phosphatase that controls endocytosis, down-regulation of mitogenic receptors and cell migratio

180 icrotubule (MT) organization by considerable down-regulation of MT polymerization via changes in the

181 Down-regulation of mTORC1 activity is required for termi

182 ession analysis also confirmed the selective down-regulation of MYC target genes by stauprimide.

183 iption factor NME2, which in turn results in down-regulation of MYC transcription.

184 hway analysis revealed a dominant pattern of down-regulation of myelin-associated genes.

185 patients who would later develop MODS, with down-regulation of neutrophil deconvolution markers.

186 imer gallate resulted in the transcriptional down-regulation of nhr-49 (an ortholog of the human pero

187 encing, and immunohistochemical examination, down-regulation of Notch pathway signaling is coincident

188 J out of the nucleus, thereby leading to the down-regulation of Notch target gene expression.

189 gun1-102-the rh50-1 mutation suppresses the down-regulation of nuclear genes for photosynthesis indu

190 ted kinases 1/2 (ERK1/2) and AKT, as well as down-regulation of octamer-binding transcription factor

191 t in endosperm-specific manner for efficient down-regulation of OsPCS genes in rice grains.

192 e to drought stress in rice achieved through down-regulation of OTS1/2 activity.

193 s of HUWE1 substrates revealed XLID-specific down-regulation of oxidative stress response DNA polymer

194 -ZO-1, and N-cadherin-ss-catenin), through a down-regulation of p-Akt1-S473 and p-Akt2-S474.

195 Down-regulation of P2X2/3R currents along the tonotopic

196 Developmental down-regulation of P2X2/3R currents along the tonotopic

197 sfer of P311 corrected the deficits, whereas down-regulation of P311 levels by lentiviral RNA interfe

198 y up-regulated miRNA required for the stable down-regulation of p53, a major suppressor of metabolite

199 this experimental system, we also observed a down-regulation of p65 phosphorylation (Ser-536) in GIMA

200 Down-regulation of PAX4 or its target gene encoding the

201 Furthermore, down-regulation of PEA15 decreases neuronal survival und

202 Here, we report that down-regulation of PECTIN METHYLESTERASE1 (PtxtPME1) in

203 s in the expression levels of several genes: down-regulation of Peg3 and Usp29 and up-regulation of Z

204 we mechanistically demonstrated concomitant down-regulation of phosphorylated extracellular signal-r

205 ation of C3 cycle enzymes, and up-regulation/down-regulation of photoprotective processes.

206 rved gene expression changes indicated major down-regulation of photosynthesis, profound and multifar

207 These results indicate that the down-regulation of photosynthetic activity could be a pl

208 Conversely, down-regulation of PKAc1 or stabilisation of a dominant-

209 Down-regulation of PKM2 by shRNA blunts cellular respons

210 depletion of HBV core protein synthesis and down-regulation of pre-genomic HBV RNA.

211 ation of NRF-2-dependent gene expression and down-regulation of proinflammatory cytokines and adhesio

212 eased miR-375 expression was associated with down-regulation of proteins involved in cellular assembl

213 rP(C) cell-surface expression was reduced by down-regulation of RAB5A, VPS28, and VPS35 and enhanced

214 ent reports showing that NED of PCa requires down-regulation of repressor element-1 silencing transcr

215 es through the monolayer and was mirrored by down-regulation of RHOA expression and myosin II activit

216 PTC7 splicing occurs at least in part due to down-regulation of ribosomal protein gene expression, le

217 Down-regulation of ROS1 in highly invasive OSCC cells, n

218 s, which could be attributed to differential down-regulation of Runx2, and up-regulation of Spp1 and

219 n vitro, Meto prevents catecholamine-induced down-regulation of S1PR1, a major cardiac protective sig

220 We also demonstrate down-regulation of several interesting, potentially pros

221 ch via CREB mediated pathways results in the down-regulation of several key enzymes in glycolysis and

222 suggest that the reduced AHP is related to a down-regulation of SK2/SK3 channel subunit expression bu

223 njury induces early cytoskeletal remodeling, down-regulation of SMPDL3b, and elevation of cellular ce

224 f Ets2 in p53 mutant mice resulted in strong down-regulation of snoRNAs and reversed the prometastati

225 Down-regulation of SOCS1 decreased the expression of epi

226 Gain of miR-146b function resulted in down-regulation of SOX5.

227 ther BCL6 controlled helper function through down-regulation of specific microRNAs (miRNAs).

228 Down-regulation of SPL4 promoted aerial bud formation an

229 mechanistic evidence that KSRP promotes the down-regulation of Spry4 by a previously unidentified me

230 C1 activity declined paralleling a selective down-regulation of SREBP target gene expression, whereas

231 The consequent up-regulation and down-regulation of stage- and subpopulation-specific gen

232 beta-klotho signaling pathways combined with down-regulation of STAT3/NFkappaB-mediated inflammatory

233 The down-regulation of SUF4 in homozygous suf4-1 ovules resu

234 iation of IgE(+) cells is accompanied by the down-regulation of surface expression of the short form

235 nd PIP2/synj1 levels after TBI, we tested if down-regulation of synj1 prevented blast-induced Tau hyp

236 Down-regulation of synj1 rescues blast-induced phospholi

237 tality which was shown to be attributable to down-regulation of target mRNA.

238 RNAi-induced down-regulation of TbHrg in heme-limited culture conditi

239 Down-regulation of TbPSD expression affected mitochondri

240 Down-regulation of TDP-43 may be involved in the tau pat

241 obvious feminization of gonads, significant down-regulation of testicular markers Amh and Sox9, and

242 The down-regulation of TET1 relieves its repression of the m

243 In contrast, severely hypothyroid mice show down-regulation of TH signaling in their livers and prof

244 Down-regulation of the ARP2/3 complex signaling pathway,

245 to TRAIL-induced apoptosis, in particular by down-regulation of the Bak-inhibitory Bcl-2 family prote

246 for ubiquitination, driving endocytosis and down-regulation of the cadherin.

247 n OVX-induced bone loss were associated with down-regulation of the caveolin-1/p53-mediated senescenc

248 stituents, the input-guided up-regulation or down-regulation of the CDN's constituents proceeds.

249 mal transition and hypoxic response, whereas down-regulation of the CPEB2A isoform did not have this

250 Down-regulation of the CPEB2B isoform inhibited pathways

251 V-1 infection in CD4(+) T cells, we observed down-regulation of the cyclin F gene (CCNF).

252 It has recently been demonstrated that down-regulation of the DeltaN form of the transcription

253 s and found that they were consistent with a down-regulation of the ecdysone pathway being involved i

254 LGI1 deficiency incurs a >50% down-regulation of the expression of Kv1.1 and Kv1.2 via

255 phagocytosis function of RPE associated with down-regulation of the expression of MERTK.

256 fibroblasts stimulated to produce podosomes, down-regulation of the G-protein ARF1 or the ARF1 guanin

257 nitrate assimilation and signaling genes and down-regulation of the G2/M cell-cycle marker gene, CYCB

258 y of L. guyanensis infection, accompanied by down-regulation of the IFN-gamma receptor normally requi

259 -regulation of the early procyclin GPEET and down-regulation of the late procyclin EP1, two proteins

260 Down-regulation of the latter GEFs differentially enhanc

261 is indicated transcriptome reprogramming and down-regulation of the NRF2-mediated antioxidant respons

262 Concomitant down-regulation of the polyubuquitinylated conjugates wa

263 sarcoplasmic reticulum Ca(2+) load due to a down-regulation of the sarcoplasmic reticulum Ca(2+)-ade

264 In particular we show evidence for the down-regulation of the STAY GREEN RICE gene and in vivo

265 inate from intestinal CD4(+) T cells through down-regulation of the transcription factor Thpok and ha

266 m proteins on the PRMT5 complex, followed by down-regulation of their encoding mRNAs.

267 RNAs, including microRNAs, with concomitant down-regulation of their protein-coding target RNAs invo

268 scription and respiratory capacity, triggers down-regulation of thermogenic genes, promoting a storag

269 Strikingly, CD40 activation resulted in down-regulation of Thioredoxin (Trx)-1 to permit ASK1 ac

270 signaling in dermal fibroblasts through the down-regulation of thrombospondin 1, a latent transformi

271 negative feedback regulation loop involving down-regulation of TLR4, IRAK1, and NF-kappaB.

272 ng in vitro diabetes, human kidney cells had down-regulation of Tyro3 and Mer mRNA and increased shed

273 ance of our observations is supported by the down-regulation of UGT1A_i2 mRNA in colon tumors compare

274 Further, down-regulation of USP48 increases E-cadherin expression

275 Down-regulation of USP48 increases K48-linked polyubiqui

276 resolved stress was accompanied by continued down-regulation of VIL1 and GSN, resulting in constituti

277 In contrast, cortisone led to down-regulation of vitellogenin.

278 s lining SC elaborate tight junctions (TJs), down-regulation of which may widen paracellular spaces b

279 In SMA mice, SMN-deficiency causes down-regulation of ZPR1 and HoxA5 that result in degener

280 articular, we observed gene length-dependent down regulation on the level of the whole tissue and gen

281 Down-regulation or insufficiency of PGRN led to the incr

282 GAPDH down-regulation potentiated H2O2-induced DNA damage and

283 ole-body fat mass, suggesting a compensatory down-regulation, presumably to prevent excessive de novo

284 nd VE-cadherin association with actin, SHP-2 down-regulation prevented ICAM-1-VE-cadherin association

285 Here, we show that PTEN down-regulation promotes liver growth in a TRAS-dependen

286 This down-regulation requires both the PH and START domains,

287 d for myogenic differentiation, whereas BRD3 down-regulation resulted in enhanced myogenic differenti

288 Ape1 down-regulation reversed the resistance of GAPDH-overexp

289 Supporting the demonstration that AHR down-regulation skews monocytes toward macrophage differ

290 ng experiments show that after orthodenticle down-regulation, the transcriptional signature of the mi

291 glucose uptake in obesity is a physiological down-regulation to prevent excessive de novo lipogenesis

292 tive splicing, which bypasses miRNA-mediated down-regulation under drought stress.

293 tive splicing to bypass miR398-mediated gene down-regulation under drought stress.

294 ion components for each dataset to represent down-regulation, up-regulation and no differential expre

295 FMRP is required for its ubiquitination and down-regulation upon Gp1 mGluR activation.

296 We show that down-regulation via RNAi of a single head patterning gen

297 -containing phosphatase-2 (SHP-2), and SHP-2 down-regulation via silencing of small interfering RNA i

298 The down regulation was confirmed by in situ hybridization h

299 n one of the winter accessions in which this down-regulation was evident, BdODDSOC2 responded to cold

300 gets with the list of genes affected by RALY down-regulation, we found an enrichment of RALY mRNA tar