ライフサイエンスコーパス: elucidate

1 despread adaptation may be very difficult to elucidate.

2 hysiological functions remain challenging to elucidate.

3 am initiator(s) of this process remain to be elucidated.

4 e negative effects on cognition remain to be elucidated.

5 er, its physiological function remains to be elucidated.

6 ver, the underlying mechanisms are not fully elucidated.

7 FPR2 in gastric cancer (GC) has not yet been elucidated.

8 fferent categories of behavior has yet to be elucidated.

9 rian cancer tumor growth have not been fully elucidated.

10 ionship to bladder cancer risk remains to be elucidated.

11 series of reactions that have not been fully elucidated.

12 re is compartmentalized has not been clearly elucidated.

13 s for Synaptotagmin activity are still being elucidated.

14 roplast lipid-degrading enzymes remain to be elucidated.

15 c inflammation in obesity remain to be fully elucidated.

16 yotic pathogen Leishmania has not been fully elucidated.

17 in host immune defense, have not been fully elucidated.

18 derlying molecular mechanisms is still being elucidated.

19 mechanisms of these responses have not been elucidated.

20 ance and optimal cutoffs are still needed be elucidated.

21 ine/dehydropiperidine synthase remains to be elucidated.

22 ovalent attachment of FAD remain to be fully elucidated.

23 ansport, but its exact function has not been elucidated.

24 ing to cis-regulatory elements remains to be elucidated.

25 in corneal wound healing have not been fully elucidated.

26 l inner-membrane (IMM) have not been clearly elucidated.

27 ercise-induced mitophagy have not been fully elucidated.

28 iferation in a fashion that has not yet been elucidated.

29 e associated with these effects remain to be elucidated.

30 e of the vast majority of them remains to be elucidated.

31 stogenic function of Bmp have not been fully elucidated.

32 However, its role has recently begun to be elucidated.

33 1/Ces1g deficiency in atherosclerosis is not elucidated.

34 the C-terminal set of five ZFs remains to be elucidated.

35 arly hematopoietic progenitors remains to be elucidated.

36 and fate in contaminated soils remain to be elucidated.

37 tions the wild-type function of genes can be elucidated.

38 verning such behavior have been difficult to elucidate [2].

39 The present studies also elucidate a key aspect of the life cycle of HK2, specifi

40 Together, these findings elucidate a major regulatory mechanism controlling the s

41 econstitution and mammalian cell culture, we elucidate a mechanism by which the coincidence of PI(4,5

42 ing the K/BxN autoimmune arthritis model, we elucidate a novel mechanism whereby oral AM80 administra

43 Together, these findings elucidate a novel RARbeta-TET2-miR-200c-PKCzeta signalin

44 Our results elucidate a probable molecular failure mechanism associa

45 Rodent studies have begun to elucidate a role of Cav1.3 L-type Ca(2+) channels in neu

46 protein frequently encountered in AMKL, and elucidate a therapeutic vulnerability in this poor-progn

47 These data further elucidated a correlation between the expression of key p

48 This study elucidated a novel cytoprotective signaling pathway init

49 Further, we elucidated a triplet stereochemical code in the stereopu

50 Our work thus elucidates a pathogenic, as opposed to protective, role

51 Our study elucidates a pivotal regulatory mechanism responsible fo

52 quate methodologies have limited progress in elucidating a causal association.

53 tational, computational, and binding studies elucidate active-site features that explain how ortholog

54 ds in a complementary manner to identify and elucidate additional classes of natural products.

55 this interaction on glass shell thickness is elucidated and the experimentally measured sensitivities

56 PP in AD and should stimulate new studies to elucidate APP-related targets suitable for pharmacologic

57 structure of the viral major capsid protein, elucidated at near-atomic resolution using cryo-electron

58 Our study elucidates at atomic level that the hydrophobicity and s

59 it is likely that interactions remain to be elucidated between miR-17-92 and as-of-yet unidentified

60 ting point for exploring molecular probes to elucidate biological functions and the therapeutic relev

61 gnized as having intricate, though not fully elucidated, biological functions at concentration regime

62 electroactive surface of the electrodes were elucidated by analyzing the calculated concentration pro

63 ts of Fe/S protein biogenesis continue to be elucidated by biochemical and ultrastructural investigat

64 Rate trends were identified and elucidated by complementary mechanistic and density func

65 ction for light-gated ion channels have been elucidated by creating channelrhodopsins with kinetics t

66 the tuber ethanolic extract and structurally elucidated by Nuclear Magnetic Resonance (NMR) spectrosc

67 a powerful functional proteomic approach to elucidate cancer-related molecular mechanisms and to dev

68 ight the potential of computational tools to elucidate causal mechanisms underlying loss of protein f

69 Ras proteins are regulated is important for elucidating cell signaling pathways and identifying new

70 Elucidating cerebellar function will require an understa

71 mately weekly sampling frequency was used to elucidate changes in virioplankton abundance and their d

72 Such information may prove advantageous in elucidating chemical class and resolving interferences.

73 hat the Drosophila nephrocyte can be used to elucidate clinically relevant molecular mechanisms under

74 ison with other peripheral membrane proteins elucidates common and specific features of this activati

75 Work there has elucidated connections between scales of development, in

76 represent novel effectors that might help to elucidate disease-specific pathways in metabolic disease

77 Here, we describe such a method for elucidating drug resistance mechanisms using genome-wide

78 high-germline risk for pancreatic neoplasia, elucidating early ontogeny in BRCA1-mutation carriers le

79 kely point of regulation for RNA editing, we elucidated endonuclease specificity in vivo.

80 alidate the utility of the Lu-iPSC model for elucidating epigenetic mechanisms contributing to pulmon

81 ity of this efflux pump is more difficult to elucidate, especially at the single-cell level.

82 n fact, archaeal MCMs are powerful tools for elucidating essential features of MCM function.

83 used to characterize Ov populations, thereby elucidating features of Ov population biology previously

84 Our findings elucidate fundamental structural aspects of the developi

85 rane and intracellular regions of ACKR3 that elucidate fundamental structural elements of agonism in

86 These mutants are a valuable resource to elucidate further how LinE proteins and the related SCs

87 Elucidating gene expression pathways promoting microglia

88 nce-based epidemiological studies to quickly elucidate genetic variation involved in the etiology of

89 ntegrative functional genomics strategies to elucidate global HCV-miRNA interactions.

90 iomedical research and provide insights into elucidating glycoprotein functions and the molecular mec

91 To elucidate Grh functions we identified embryonic Grh targ

92 genicity, their further study should help to elucidate host-virus interactions that determine acute a

93 ction and establish a proteomic resource for elucidating host mechanisms that regulate fungal intrace

94 Future studies might elucidate how brain diseases change this modular archite

95 light scattering, and electron microscopy to elucidate how EGCG remodels Abeta oligomers.

96 To elucidate how gradient characteristics govern cellular r

97 t demonstration of an integrated approach to elucidate how heterogeneity at the transcriptional level

98 These analyses elucidate how projected climate change can negatively al

99 uantitative single-cell studies has begun to elucidate how signaling dynamics determine cell physiolo

100 Animal models have begun to elucidate how skin barrier defects can lead to systemic

101 These results elucidate how surface atomic structures determine the re

102 re we employed iterative deletion mapping to elucidate how the NTD of HSPB6 influences its preferenti

103 However, it remains to be fully elucidated how progression of secondary growth is proper

104 eruleus Although many open questions remain, elucidating how cells repair themselves is important for

105 ng immunological memory formation depends on elucidating how multipotent memory precursor (MP) cells

106 A unwinding with synthesis is starting to be elucidated, however the architecture and dynamics of the

107 2D immunoblots were made in parallel to elucidate IgE and IgG reactivity, and putative function

108 ll three fields have considerable promise in elucidating important issues in plant domestication and

109 these strategies to cell division mechanisms elucidated in model organisms.

110 Numerous studies that elucidate its composition were exclusively focused on de

111 ing the substrates of an E3 holds the key to elucidate its role in cell regulation.

112 how natural hosts avoid immunodeficiency can elucidate key mechanisms of pathogenesis.

113 Our microsecond-long atomistic simulations elucidate key structural differences between monomeric A

114 incompletely characterized proteins and for elucidating larger-scale patterns of proteome organizati

115 naling transcriptional repression of 15-PGDH elucidates long sought-after molecular mechanisms that g

116 To elucidate major histocompatibility complex-linked system

117 in MPO biosynthesis and processing have been elucidated, many questions remained, such as the structu

118 Although much work has been done to elucidate mechanisms of cluster formation, it almost exc

119 attention deficit hyperactivity disorder can elucidate mechanisms that contribute to the disorder, wh

120 parallels human disease and has been used to elucidate mechanistic aspects of a virus induced biliary

121 In addition, this methodology may help elucidate mechanistic pathways linking diet to chronic d

122 To develop 4-dimensional methodologies for elucidating microarchitecture and function of the recons

123 Hall, Michael Rosbash, and Michael Young for elucidating molecular mechanisms of the circadian clock.

124 s-based sampling and modelling approaches to elucidate multiple dimensions of historical population i

125 er-sphere ion clusters in organic solutions, elucidating new strategies for controlling ion cluster a

126 nsing mechanical and chemical cues have been elucidated over the past three decades, the mechanisms t

127 iagnostic imaging and radiation therapy have elucidated parts of this enigma.

128 in a mouse model of atopic dermatitis and to elucidate possible HOCl's mode of action.

129 This study aimed to elucidate potential clinical and biological function of

130 oprotein biosynthesis by the antibiotics and elucidate potential side effects.

131 that previously described for the rat, thus, elucidating potential neuronal pathways involved in the

132 ture-based mechanism of bifurcation has been elucidated recently for the flavin-based enzyme NADH-dep

133 cellular models might be employed to further elucidate relevant epistatic interactions.

134 s aimed at identifying candidate gene(s) and elucidating resistance mechanisms induced by barley resi

135 addition to alkenes as the model process, we elucidate several key mechanistic principles.

136 s between allergy and autoimmune diseases to elucidate shared disease mechanisms.

137 power to discover genetic variants and could elucidate shared molecular genetic mechanisms.

138 There remains, however, a pressing need to elucidate striatal SPN firing in the context of the sync

139 s reported herein can be utilized to further elucidate structural requirements of alpha-syn fibril gr

140 ered when using experimental Omega values to elucidate structures in solution.

141 picture of potential biases in the data and elucidate subtle phylogeographic patterns.

142 To elucidate such requirements, we used a V(D)J passenger a

143 Elucidating such novel neural endophenotypes can facilit

144 Free-energy simulations elucidate the active site conformations in the AppA (act

145 The objective of this study was to elucidate the ArsI mechanism.

146 the Pediatric Contact Dermatitis Registry to elucidate the associations and sensitizations among pati

147 Here, we elucidate the atomic-level nature of Cs and Rb incorpora

148 To elucidate the behavioral role of the cotransmission, we

149 These provide clues to elucidate the binding site parameters and mechanism of P

150 These data elucidate the broad transcriptional changes that these b

151 Further studies are necessary to elucidate the causal direction of this association and t

152 have used the epidermis as a model system to elucidate the cellular effects and signaling feedback se

153 We elucidate the complex dependence of selectivity on a fra

154 ipotent stem cells could potentially help to elucidate the complex mechanisms of the disease and lead

155 upling highly specific process indicators to elucidate the complexity of carbon cycling in these ecos

156 We review the current findings that elucidate the components, timing, and kinetics of the mu

157 To elucidate the contribution of FOXP1-mediated signaling t

158 Here, we elucidate the contributions of the Cas10-Csm complex tow

159 roscopic imaging and phase-field modeling to elucidate the delithiation dynamics of single-crystal li

160 of both recessed nanodiscs and nanorings to elucidate the differences in mass transport between thes

161 Taken together, these findings elucidate the differences in trogocytosis and HA formati

162 using an environmental gas cell in order to elucidate the different porous forms of the breathing fr

163 To elucidate the dynamic transcriptional changes that under

164 ntal line(C horizontal line)mO], in order to elucidate the electronic origin of the curious "kinked'"

165 tions and spectroelectrochemical experiments elucidate the electronic structure and redox thermodynam

166 ctional aspects of allelic diversity help to elucidate the evolution of polymorphic genes involved in

167 Accordingly, in the present work, we elucidate the facets of this Mphi Fv3 susceptibility and

168 al and molecular-based techniques, begins to elucidate the FH heterogeneity and the mutation spectrum

169 flow cytometry and Western blot analysis to elucidate the function and structural biology of glycopr

170 Our findings also elucidate the functional implications of the decades-old

171 ynthesis, morphology, and device physics) to elucidate the fundamental, underlying principles that go

172 fibre metabolism characterization, helped to elucidate the general picture of the advanced stage of p

173 To elucidate the history of arsenic adaptation across the t

174 To elucidate the IL-36 activation mechanism, we considered

175 To elucidate the importance of the GPB and GPC receptors re

176 Overall, these findings elucidate the intimate relationship between water-protei

177 Bayesian model calibration and synthesis to elucidate the key physiological parameters that drive un

178 We used an adoptive transfer model to elucidate the kinetics of the effector CD8(+) T cell res

179 ed to understand the overall performance and elucidate the limiting reactions of the photobioelectroc

180 Our findings not only elucidate the mechanism governing the tunable Fano reson

181 To elucidate the mechanism linking [K(+)] and T-wave, we al

182 5745.MMP9 complex and biochemical studies to elucidate the mechanism of inhibition of MMP9 by GS-5745

183 untries of the Greater Mekong subregion, and elucidate the mechanism of piperaquine resistance.

184 45 on the cervical epithelial barrier and to elucidate the mechanisms by which these miRNAs modify ce

185 Here we use Drosophila neural stem cells to elucidate the mechanisms involved in physical asymmetry

186 ated under various disinfection scenarios to elucidate the mechanisms of Br-DBP formation.

187 ronectin features to mimic fibrillar ECM and elucidate the mechanisms of contact guidance.

188 mprehensive kinetic model was established to elucidate the mechanisms of radical generation and miner

189 body surface electrocardiographic mapping to elucidate the mechanisms of VT.

190 fic immune cell populations in the Fulani to elucidate the mechanisms that confer the lower susceptib

191 the fungus and several studies have begun to elucidate the mechanisms that control the plant processe

192 To elucidate the mechanisms that modulate the population di

193 tumor-promoting role for TCF7L1 in skin and elucidate the mechanisms underlying its tumorigenic capa

194 ardiac mechano-signaling network in order to elucidate the mechanisms underlying signal integration.

195 neonatal rat cardiomyocyte culture system to elucidate the mechanisms underlying these observations.

196 cal and biochemical methods were utilized to elucidate the mechanistic details and evolutionary trade

197 The aim of this study was to elucidate the microstructural, textural, and sensory imp

198 This study therefore aimed to elucidate the modulating effect of environment (i.e. cog

199 Our findings elucidate the molecular basis underlying inter-segment i

200 To elucidate the molecular functions of the ATG8 proteins,

201 responses during droughts and contributes to elucidate the molecular mechanisms involved under this e

202 To elucidate the molecular mechanisms underlying these dise

203 sclerosis, and ulcerative colitis and hereby elucidate the molecular mechanisms underpinning these di

204 ction of the bacterial cells with Al NPs and elucidate the nanoshielding mechanism via UV plasmonic r

205 rther assessment of antibody repertoires may elucidate the nature of antipneumococcal antibody-mediat

206 ropic), quantitative MRI technique to better elucidate the neuroanatomical underpinnings of individua

207 We aimed to elucidate the origin and hydrological pathways of BTs in

208 irm the suggested reaction mechanisms and to elucidate the origin of the electrophilic reactivities.

209 although further monitoring is encouraged to elucidate the origin of the highest (240)Pu/(239)Pu atom

210 G knockout (KO) mouse model was generated to elucidate the pathogenesis of absent ENaC function in th

211 g epileptic seizures by (18)F-FET PET and to elucidate the pathophysiologic background.

212 cates clinical care and confounds efforts to elucidate the pathophysiology of commonly occurring symp

213 tial signaling results, we sought to further elucidate the pathway by which G1 can activate NFAT luci

214 l intermediates during CCC DNA formation and elucidate the pathways and factors involved.

215 To elucidate the pathways of perforin pore assembly, we car

216 the use of molecular modeling simulations to elucidate the phase-change mechanism, including the ener

217 Additional investigation to elucidate the precise mechanism underlying gene-length d

218 The purpose of this study was to elucidate the predictive significance of MPV in CRC.

219 own, which could serve as a powerful tool to elucidate the process of divergent radiations, colonizat

220 Future studies are needed to elucidate the provenance and putative neurotoxicity of f

221 ancer cells, providing a strong rationale to elucidate the regulatory mechanisms for these systems.

222 To conclude, our results elucidate the relation between dynamic network reconfigu

223 -throughput 18 S ribosomal DNA sequencing to elucidate the relationship between eukaryotic plankton c

224 omputed tomography (micro-CT) was applied to elucidate the relationship between the three-dimensional

225 veral network models have been introduced to elucidate the relationships between diseases.

226 skite nanocrystals (NCs) as model systems to elucidate the role of heterovalent doping on charge-carr

227 Next, to elucidate the role of keratinocyte gene expression in la

228 Although further research is needed to elucidate the role of myelin in affecting emotional, cog

229 These observations elucidate the role of roughness in colloid attachment un

230 The aim of this study was to elucidate the role of this descending pathway in the per

231 and metagenomes in these model systems, (3) elucidate the rules of synthetic, functionally programma

232 tins are dimeric and it is thus important to elucidate the short- and long-range recognition mechanis

233 To elucidate the signaling mechanism, a gene expression tim

234 Further studies are needed to elucidate the source and epidemiology of PCR ribotype 26

235 lishes a modeling and experimental method to elucidate the structural dynamics underlying substrate s

236 encing and molecular dynamics simulations to elucidate the substitution pattern in softwood xylans an

237 us, we demonstrated that paAIP2 is useful to elucidate the temporal window of CaMKII activation requi

238 Therefore, our results elucidate the tumor-suppressor role of SPOP in prostate

239 n functional information into GWASs can help elucidate the underlying biological mechanisms and prior

240 This study aimed to elucidate the underlying mechanism of differential regul

241 lar responses to 3D hypoxic gradients and to elucidate the underlying mechanisms governing these resp

242 ation between NM-GHGs and M-GHGs, to further elucidate the underlying mechanisms, to investigate the

243 To elucidate the underlying regulatory mechanisms of OsHAD1

244 he homogeneous atomic Fe model catalysts, we elucidated the active site formation process through cor

245 n, and molecular dynamics simulation studies elucidated the binding site of these aniline-based influ

246 We will here review key findings that have elucidated the central neuroendocrine mechanism of sleep

247 Our findings elucidated the common origin of all CS-PPR converter gen

248 Here, we have elucidated the functional consequences of a NaV1.9 mutat

249 Similarly, we elucidated the importance of certain Tau protein regions

250 Recent studies have elucidated the metabolic role of JAK2, a key mediator do

251 In this study, we elucidated the neuronal mechanism underlying the respons

252 Previous work has elucidated the regulatory mechanisms of p300 acetyltrans

253 lipoprotein E-deficient (ApoE(-/-)) mice and elucidated the role of TSP-1 in this process.

254 We further elucidated the signaling downstream of Gq and identified

255 ublished and unpublished sources, this paper elucidates the development of specific treatments for ao

256 Electron spin resonance measurement elucidates the ferromagnetic nature of ZnCoO by the form

257 antioxidant activity, and, at the same time, elucidates the mechanisms involved in this activity.

258 Our work elucidates the molecular mechanism for histone depositio

259 s allows full comparison with dicot CADs and elucidates the potential signature sequence for their su

260 This review elucidates the role of AXL in EMT-mediated oncogenesis a

261 ructure of the Na(+)-selective AtTPC1 mutant elucidates the structural basis for Na(+) selectivity in

262 nsitions between transcriptional states, and elucidates the temporal order, functional role and mecha

263 [Formula: see text] This locality principle elucidates the transferability of functional groups in c

264 e presence of both these activities in Icp55 elucidates the unexplained processing of the mitochondri

265 cA is still lacking and will be critical for elucidating the bacterial protein transport mechanism.

266 eart rate (f H ) has been used as a tool for elucidating the balance between sympathetic and parasymp

267 We reasoned that by elucidating the basis of microcephaly in AS, a highly pe

268 Elucidating the binding mode of carboxylate-containing l

269 g large-scale metabolomics data, methods for elucidating the biochemical structure and function of no

270 wo decades, multiple studies have focused on elucidating the causative factors underlying memory defe

271 Elucidating the composition of waxes is of utmost import

272 While great strides have been made toward elucidating the cytoplasmic components of MAPK signaling

273 useful for preclinical drug studies and for elucidating the developmental origins of pediatric neopl

274 lustrate the power of synthetic chemistry in elucidating the fundamental mechanisms underlying electr

275 suppressive and antiretroviral regimens, and elucidating the incidence of rejection in HIV-to-HIV sol

276 However, elucidating the molecular adaptions that produce toleran

277 Elucidating the molecular basis of these effects, mutati

278 nal, and structural findings directed toward elucidating the molecular factors that drive pi-clamp-me

279 proxies therefore offer a novel approach for elucidating the phenomenology of the nuclear fireball as

280 Toward elucidating the response of this modular protein to mech

281 o synthesize and test FAHFAs was critical in elucidating the roles of these lipids, but these studies

282 xt of a protein fold provides a strategy for elucidating the sequence-structure-fitness relationships

283 Elucidating the structures of these trimers and higher-o

284 olyte composition and effective pore size to elucidate their influence on separation mechanisms for i

285 ysis of the T cells involved in insulitis to elucidate their role in the etiology of T1D.

286 and ER-LIKE1 (ERL1) receptor-kinase genes to elucidate their roles in secondary growth.

287 Critical to elucidating their physiological role is the opportunity

288 and C horizontal lineO...H2O hydrogen bonds, elucidating their role in the brush's temperature-induce

289 Future research should further elucidate these associations with detailed eruption data

290 comprehensive studies are needed to further elucidate this disease, which could ultimately offer pre

291 A two-step mechanism was elucidated through detailed kinetic analyses and suggest

292 of TFs in mouse tissues that can be used to elucidate transcriptional regulatory specificity and pro

293 duct has been observed, and its constitution elucidated unambiguously by (13)C and (15)N isotopic lab

294 biology approaches: "Orbital-deconvolution" elucidated upstream, regulatory pathways interconnecting

295 of insects on host-plant populations can be elucidated via several stage-structured life tables of p

296 che modeling to evaluate plant responses and elucidate vulnerabilities to climate change.

297 ation and management, further studies should elucidate whether the efficacy of ectoparasite removal b

298 onsible for each phase of the hair cycle, or elucidate which proteolysis products from keratinocytes

299 between molecules, which are challenging to elucidate with current techniques.

300 IL-10 expression by CD4(+) T cells are being elucidated, with several cytokines implicated.