ライフサイエンスコーパス: gastrin

1 sphorylation and cell motility stimulated by gastrin.

2 ity to the regulation of G-cell secretion of gastrin.

3 TFF1, which can be suppressed by the hormone gastrin.

4 , gastric acid content, and plasma levels of gastrin.

5 eptor for cholecystokinin (CCK) and amidated gastrin.

6 ccurring forms and extensive similarities to gastrin.

7 een associated with elevated levels of serum gastrin.

8 otection against injury by administration of gastrin.

9 MKN45 cells were cocultured with IFNgamma or gastrin.

10 y reduced fundic expression of both Pdx1 and gastrin.

11 ion of STAT3 in the MKN45 cell line, but not gastrin.

12 timulates the G-cells to produce and secrete gastrin.

13 f the antral gastric mucosa does not require gastrin.

14 cells, to assess proliferative responses to gastrin.

15 ecificity, phytaspase was shown to hydrolyze gastrin-1 and cholecystokinin at the predicted sites in

16 e normal, except for the elevation of plasma gastrin (1031 pg/ml; reference value <108) and chromogra

17 f pepsinogen 1 (PG1), pepsinogen 2 (PG2) and gastrin 17 (G17) offers the possibility to detect preneo

18 ected for Helicobacter pylori, HIV serology, gastrin-17, and pepsinogen 1 and 2 concentrations.

19 tokinin-2 receptor was treated with amidated gastrin-17.

20 vasoactive intestinal peptide (5 patients), gastrin (2 patients), or glucagon (4 patients).

21 l (nl <2.5), PTH i = 243 pg/mL (nl <65), and gastrin = 6950 pg/mL (nl < 100).

22 orectal cancer, FAK is activated by amidated gastrin, a protumorigenic hormone.

23 Here we show that gastrin, a stomach hormone typically expressed in the pa

24 mulants of acid secretion include histamine, gastrin, acetylcholine, and ghrelin.

25 mulants of acid secretion include histamine, gastrin, acetylcholine, and ghrelin.

26 Gastrin, acting via cholecystokinin-2 receptors on enter

27 Gastrin, acting via gastrin/cholecystokinin-B (CCK-B), n

28 and HDAC7 with HDC promoter, suggesting that gastrin activates HDC gene expression at least partly by

29 Gastrin also exerts trophic effects on various tissues,

30 erum inflammatory mediators, antibodies, and gastrin among germfree and H pylori-monoinfected INS-GAS

31 letion of the pentaglutamate sequence in the gastrin analogs lowered the tumor uptake by a factor of

32 ognized for decades as potent stimulants for gastrin and acid secretion, although the molecular basis

33 pecific calcimimetic, cinacalcet, stimulated gastrin and acid secretion, whereas the calcilytic, NPS

34 as the elusive physiologic sensor regulating gastrin and acid secretion.

35 matory infiltrate are capable of stimulating gastrin and acid secretion.

36 the human gastrointestinal peptide hormones gastrin and cholecystokinin.

37 Both gastrin and gastrin-receptor knockout mice as well as ga

38 wth factor gastrin, and mice mutant for both gastrin and Hip1r exhibited normalization of both prolif

39 L cells are coupled by the couplet molecules gastrin and histamine and by a prior asymmetrical cell d

40 A chemical complex of gastrin and histamine is postulated as is also the asymm

41 tric cancer in INS-GAS mice that overexpress gastrin and IL-8Tg mice infected with Helicobacter felis

42 one has led to new research into the role of gastrin and its receptor (cholecystokinin-2 receptor) in

43 through the upregulation of plasma levels of gastrin and matrix metalloproteinase expression.

44 We also found that the levels of gastrin and p73 transcripts correlate in primary gastric

45 lates all enteroendocrine cell types, except gastrin and preproglucagon.

46 cells from C57BL/6 mice were incubated with gastrin and separated into nuclear and cytoplasmic fract

47 Moreover, gastrin and Sst gene expression did not change in respon

48 stimulants of acid secretion are the hormone gastrin and the paracrine amine histamine.

49 as a new effector for Galpha13 downstream of gastrin and the type 2 cholecystokinin receptor.

50 retion from the parietal cell are histamine, gastrin, and acetylcholine.

51 stimulants of acid secretion are histamine, gastrin, and acetylcholine.

52 centages of circulating intact somatostatin, gastrin, and bombesin radiopeptides in mouse models, res

53 d decrease in antral cilia, increased plasma gastrin, and gastric acidity.

54 ased expression of the gastric growth factor gastrin, and mice mutant for both gastrin and Hip1r exhi

55 red that membrane-associated ANX II binds PG/gastrins, and partially mediates growth factor effects o

56 The combination of CCK2/gastrin- and histamine H2-receptor antagonists has syner

57 rming growth factor-alpha, amphiregulin, and gastrin; and activation of extracellular signal-regulate

58 These results reveal the fetal hormone gastrin as a novel marker for reversible human beta-cell

59 cted of possibly having ZES, the appropriate gastrin assay to use, the role of surgery in patients wi

60 2 receptor mRNA abundance and increased 125I-gastrin binding was demonstrated in IEC-6 cells followin

61 d earlier reported the presence of 33-36 kDa gastrin-binding proteins on cellular membranes of colon

62 e combination of epidermal growth factor and gastrin, can stimulate regeneration of beta-cells in viv

63 Diffuse gastrin cell hyperplasia precedes the appearance of MEN1

64 expressed in antral mucosal cells including gastrin cells and TFF2-expressing deep glandular mucous

65 n parietal, enterochromaffin-like (ECL), and gastrin cells.

66 ence on parietal, enterochromaffin-like, and gastrin cells.

67 production of duodenal GIP cells and stomach gastrin cells.

68 raint on parietal, enterochromaffinlike, and gastrin cells.

69 , nitric oxide, and galanin), hormonal (e.g. gastrin, cholecystokinin, and ghrelin), paracrine (e.g.

70 Gastrin/cholecystokinin subtype 2 receptors (CCK-2Rs) ar

71 The gastrin/cholecystokinin-2 (CCK-2) receptor has been iden

72 Gastrin, acting via gastrin/cholecystokinin-B (CCK-B), now termed CCK2, rece

73 d with increased basal and stimulated plasma gastrin concentrations and acid outputs.

74 had increases in glucagon-like peptide-1 and gastrin concentrations that were expected with treatment

75 fibrillary acidic protein (GFAP+) expressed gastrin de novo through a mechanism that required PKA.

76 nd histology of 12-month-old wild-type (WT), gastrin-deficient (G-/-) and somatostatin-deficient (SOM

77 investigated in hypergastrinemic (INS-GAS), gastrin-deficient (GAS(-/-)), Tff1-deficient (Tff1(+/-))

78 However, gastrin-deficient (GAS-KO) mice on a mixed C57BL/6/129Sv

79 -Shh(KO)) and hypergastrinemia, crossed with gastrin-deficient (GKO) mice (PC-Shh(KO)/GKO).

80 In contrast, homozygous gastrin-deficient and heterozygous Tff1-deficient mice s

81 Acute parietal cell loss in gastrin-deficient mice treated with DMP-777 leads to the

82 Emerging SPEM lineages in gastrin-deficient mice treated with DMP-777 were examine

83 rophic gastritis from hypochlorhydria in the gastrin-deficient mouse predisposes the stomach to gastr

84 mined the intracellular mechanisms mediating gastrin-dependent gene expression.

85 Gastrin differentially induces COX-2 and IL-8 expression

86 The peptide hormone gastrin exerts a suppressive effect on antral gastric ca

87 in gene and induces generation of submucosal gastrin-expressing cell hyperplasia.

88 Gastrin expression in adult beta-cells does not involve

89 in in mice is expressed in insulin(+) cells, gastrin expression in humans with T2D occurs in both ins

90 In vivo and in vitro experiments show that gastrin expression is rapidly eliminated upon exposure o

91 netic lineage tracing in mice indicates that gastrin expression is turned on in a subset of different

92 Gastrin expression was co-localized with HDC expression

93 The gastrin (from G-cells) stimulates the ECL cells to produ

94 Gastrin, from G-cells, and histamine, from enterochromaf

95 Amidated gastrin (G-17) attenuated the growth suppressing effects

96 roduct of the gastrin gene (glycine-extended gastrin (G-gly)) as a new ligand for the F(1)-ATPase.

97 identified a peptide hormone product of the gastrin gene (glycine-extended gastrin (G-gly)) as a new

98 igated how menin regulates expression of the gastrin gene and induces generation of submucosal gastri

99 ed production of somatostatin, and increased gastrin gene expression.

100 recent developments in the biology of other gastrin gene products, including the precursor progastri

101 tigated the role of p73 in regulation of the gastrin gene promoter.

102 onstrate a novel mechanism for regulation of gastrin gene transcription and support a concept that p5

103 ed and incompletely processed product of the gastrin gene, has been shown to induce colonic hyperprol

104 cyclase-activating peptide), hormonal (e.g., gastrin, ghrelin, and apelin), and paracrine (e.g., hist

105 y cilia on gastric endocrine cells producing gastrin, ghrelin, and somatostatin (Sst), hormones regul

106 rum chromogranin A, neuron-specific enolase, gastrin, glucagon, vasoactive intestinal peptide, pancre

107 ease of enteroendocrine cell types including gastrin-, glucagon/GLP-1-, CCK-, secretin-producing cell

108 role of histamine as a downstream target of gastrin has not been fully explored.

109 ollowing injury, but the effects of amidated gastrin have not previously been assessed.

110 nsforming growth factor-alpha, and endocrine gastrins have been implicated in the tumorigenic potenti

111 Gastrin, histamine, acetylcholine, and ghrelin stimulate

112 actor, and neuromedin U) and peripheral (eg, gastrin, histamine, acetylcholine, somatostatin, cholecy

113 The major stimulants of acid secretion are gastrin, histamine, and acetylcholine.

114 ine inhibitory influence on the secretion of gastrin, histamine, and acid secretion.

115 Gastrin, histamine, gastrin-releasing peptide, ghrelin,

116 se results support an important role for the gastrin-histamine axis in Helicobacter-induced gastric c

117 R, revealing similar up-regulation of Sox-2, Gastrin, HoxA5, GATA4/5/6, Villin and Forkhead 6 (Foxl1)

118 (CCKS) and doubly protonated Tyr12-sulfated gastrin II (GST) resulted in complete loss of SO3 from a

119 meal-stimulated acid secretion by releasing gastrin in a variety of laboratory animals, recent studi

120 uggest a role of processing intermediates of gastrin in colon carcinogenesis.

121 s demonstrate that the trophic properties of gastrin in CRC may be mediated in part by transactivatio

122 Therefore, we investigated the role of gastrin in Helicobacter-associated gastric carcinogenesi

123 cells (eg, p75 and S100B), colocalized with gastrin in human duodenal gastrinomas.

124 Although gastrin in mice is expressed in insulin(+) cells, gastri

125 The existence of the hormone gastrin in the distal stomach (antrum) has been known fo

126 focus on the role of endocrine and autocrine gastrins in colon cancer and review recent advances that

127 udies also provide support for the idea that gastrin, in concert with other hormones, could potential

128 ew we consider important additional roles of gastrin, including regulation of genes encoding proteins

129 Gastrin increased the stability of both COX-2 and IL-8 m

130 reased, whereas gastric acid and circulating gastrin increased.

131 n-positive cells; increased levels of plasma gastrin; increased expression of transforming growth fac

132 Gastrin induced COX-2 and IL-8 expression in AGS-E cells

133 colon carcinoma cells depleted of Galpha13, gastrin-induced FAK Tyr(P)-397 and paxillin Tyr(P)-31 ph

134 Gastrin-induced nuclear export of menin via cholecystoki

135 antagonists of WNT and Smoothened inhibited gastrin-induced proliferation and WNT activity.

136 Ihh signaling mediates gastrin-induced proliferation of epithelial cells in sto

137 Gastrin induces the expression of cyclooxygenase (COX)-2

138 Gastrin infusion of PC PC-Shh(KO)/GKO mice increased exp

139 PC-Shh(KO)/GKO mice were given gastrin infusions for 7 days; gastric surface epithelium

140 d in transgenic mice overexpressing amidated gastrin (INS-GAS) and mice in which hypergastrinemia was

141 Transgenic FVB/N insulin-gastrin (INS-GAS) mice have high circulating gastrin lev

142 Autocrine gastrins, insulin-like growth factor-II, transforming gr

143 Gastrin is a key regulator of gastric acid secretion.

144 Gastrin is a peptide hormone and an important factor in

145 e gastric corpus and antrum, suggesting that gastrin is an essential cofactor for gastric corpus carc

146 Gastrin is involved in the endocrine regulation of gastr

147 The recognition that gastrin is not only a secretagogue but also a trophic ho

148 Gastrin is the only hormone capable of stimulating gastr

149 e that express a human progastrin transgene, gastrin knockout mice, and C57BL/6 mice (controls); the

150 ter secretin stimulation testing, the plasma gastrin level rose to 3789 pg/ml.

151 owed lower cilia numbers and acid but higher gastrin levels than mice fed a standard diet, suggesting

152 In fed Ift88(-/fl) mice, gastrin levels were higher, and gastric acidity was lowe

153 gastrin (INS-GAS) mice have high circulating gastrin levels, and develop spontaneous atrophic gastrit

154 Ngn3(-)(/)(-) mice, which also show reduced gastrin levels, express Nkx6.3 normally.

155 inhibits acid secretion and increases serum gastrin levels, factors strongly associated with cancer

156 f unknown cause and screened for using blood gastrin levels.

157 nstitutive achlorhydria, and elevated plasma gastrin levels.

158 polymerase chain reaction (qPCR), and serum gastrin levels.

159 aging studies had lower preoperative fasting gastrin levels; had a longer delay before surgery; more

160 Gastrin-mediated Akt activation was observed to be downs

161 nt in AGS cells led to increases in Pdx1 and gastrin messenger RNA expression.

162 for 42%-69% of cells in gerbils and insulin-gastrin mice with dysplasia and carcinoma.

163 both wild-type and hypergastrinemic insulin-gastrin mice, using immunohistochemistry and flow cytome

164 These mice show markedly reduced gastrin mRNA, many fewer gastrin-producing (G) cells in

165 his leads to transcriptional upregulation of gastrin mRNA.

166 We have shown previously that gastrin-null mice display gastric atrophy and metaplasia

167 These results point to a distinct effect of gastrin on carcinogenesis of both the gastric corpus and

168 We therefore investigated the effects of gastrin on intestinal regeneration following a range of

169 amma expression might mediate the effects of gastrin on the proliferation of colorectal cancer (CRC).

170 nd gastrin-receptor knockout mice as well as gastrin-overexpressing and cAMP-overexpressing mice deve

171 -tetraacetic acid (DOTA)-conjugated divalent gastrin peptides based on the C-terminal sequence of min

172 ynthesized and screened a series of divalent gastrin peptides for improved biochemical and biologic c

173 o-labeled gastrins to membrane proteins from gastrin/PG responsive cell lines.

174 ow markedly reduced gastrin mRNA, many fewer gastrin-producing (G) cells in the stomach antrum, hypog

175 Our results show that p73 can bind to the gastrin promoter.

176 d with Helicobacter felis and given the CCK2/gastrin receptor antagonist YF476 and/or the histamine H

177 (400 ppm in drinking water) alone, the CCK2/gastrin receptor antagonist YM022 (45 mg/kg/wk) alone, a

178 is unclear how FAK receives signals from the gastrin receptor or other G-protein-coupled receptors th

179 e variants of the cholecystokinin-2 (CCK(2))/gastrin receptor; however, their relative contributions

180 Both gastrin and gastrin-receptor knockout mice as well as gastrin-overex

181 ported the presence of novel progastrin (PG)/gastrin receptors on normal and cancerous intestinal cel

182 LD-1 expressed both functional PPARgamma and gastrin receptors.

183 te with gastric atrophy, we examined whether gastrin regulates Shh expression in parietal cells.

184 Bombesin-induced gastroprotection and gastrin release are modified by somatostatin.

185 Gastrin release was stimulated by forskolin (adenosine 3

186 Gastrin release was stimulated by neuronal G protein-cou

187 hanical strain stimulated (2-fold to 8-fold) gastrin release, and decreasing pH from 7.4 to 5.5 inhib

188 onist MRS1754 inhibited mechanically induced gastrin release.

189 esin to prevent gastric injury by increasing gastrin release.

190 The antral hormone gastrin, released by activation of cholinergic and bombe

191 Pro-gastrin releasing peptide (pro-GRP) was identified as a

192 says are in high demand, and analysis of pro-gastrin releasing peptide (ProGRP) as a small cell lung

193 Bioconjugate affinity for the gastrin releasing peptide receptor (GRPR) as determined

194 into tumor cells, their affinity toward the gastrin releasing peptide receptor (GRPr), metabolic sta

195 e been proposed for diagnosis and therapy of gastrin releasing peptide receptor (GRPR)-expressing tum

196 Gastrin releasing-peptide (GRP) is a potent growth facto

197 483 cells with siRNA causes an inhibition of gastrin-releasing peptide (GRP) -induced phosphorylation

198 halocyanine-peptide conjugates targeting the gastrin-releasing peptide (GRP) and integrin receptors i

199 The gastrin-releasing peptide (GRP) and its receptor (GRPR)

200 for the oncogenic transformations induced by gastrin-releasing peptide (GRP) and its receptor, GRP-R,

201 of a cohort of itch-sensing genes, including gastrin-releasing peptide (GRP) and MAS-related GPCR mem

202 NeuroD2 that contribute to these processes: gastrin-releasing peptide (GRP) and the small conductanc

203 Bombesin (BN) or gastrin-releasing peptide (GRP) can stimulate the growth

204 only vasoactive intestinal polypeptide (VIP)/gastrin-releasing peptide (GRP) cells located ventrally

205 ctions of spinal opioid-related peptides and gastrin-releasing peptide (GRP) in awake, behaving monke

206 Brief light pulses or microinjection of gastrin-releasing peptide (GRP) into the third ventricle

207 Gastrin-releasing peptide (GRP) is a neuropeptide that a

208 Previous studies suggested that gastrin-releasing peptide (GRP) is an itch-specific neur

209 Gastrin-releasing peptide (GRP) is localized to the SCN

210 Gastrin-releasing peptide (GRP) is synthesized by pulmon

211 ning the adult colon do not normally express gastrin-releasing peptide (GRP) or its receptor (GRPR).

212 Gastrin-releasing peptide (GRP) receptors (GRPr) are fre

213 tides have demonstrated high affinity toward gastrin-releasing peptide (GRP) receptors in vivo that a

214 We have previously shown that gastrin-releasing peptide (GRP) stimulates neuroblastoma

215 Two probes for gastrin-releasing peptide (GRP), a known stimulatory ago

216 epolarization and a second SCN neuropeptide, gastrin-releasing peptide (GRP), can acutely enhance and

217 hetamine-related transcript (CART), galanin, gastrin-releasing peptide (GRP), neuropeptide Y (NPY), n

218 Gastrin-releasing peptide (GRP), secreted by pulmonary n

219 oxide, vasoactive intestinal peptide (VIP), gastrin-releasing peptide (GRP), substance P, and calcit

220 a subset of spinal interneurons, labeled by gastrin-releasing peptide (Grp), that receive direct syn

221 Exemplified by gastrin-releasing peptide (GRP), these neuropeptides tra

222 Gastrin-releasing peptide (GRP), which is found within c

223 ied 5-HT1A as a key receptor in facilitating gastrin-releasing peptide (GRP)-dependent scratching beh

224 PAR-4 was also found on gastrin-releasing peptide (GRP)-positive neurons (pruric

225 ibutions from arginine vasopressin (AVP) and gastrin-releasing peptide (GRP).

226 ry afferent-derived "itch" neurotransmitter, gastrin-releasing peptide (GRP).

227 A gastrin-releasing peptide (GRP)/GRP receptor-mediated au

228 Normally, levels of mammalian bombesin (gastrin-releasing peptide [GRP]) drop postnatally, but t

229 of the mitogenic neuropeptide receptors for gastrin-releasing peptide and arginine vasopressin.

230 ed release of the pruritogenic neuropeptides gastrin-releasing peptide and atrial natriuretic peptide

231 lease of the itch and analgesia transmitters gastrin-releasing peptide and leucine-enkephalin.

232 ropeptides of the bombesin family, including gastrin-releasing peptide and neuromedin B, which are fo

233 ranscription that regulate these parameters: gastrin-releasing peptide and the small conductance, cal

234 ry adenylate cyclase-activating peptide, and gastrin-releasing peptide have shown how these peptides

235 We found that gastrin-releasing peptide is specifically expressed in a

236 ed by activation of cholinergic and bombesin/gastrin-releasing peptide neurons, acts mainly by releas

237 Receptor-targeted agents, such as gastrin-releasing peptide receptor (BB2r)-targeted pepti

238 ed by cells expressing the G-protein-coupled gastrin-releasing peptide receptor (GRP-R) and is curren

239 imilar rationale, radioligands targeting the gastrin-releasing peptide receptor (GRP-R) might offer a

240 However, the limited expression of gastrin-releasing peptide receptor (GRPR) and integrin a

241 We recently introduced the potent gastrin-releasing peptide receptor (GRPR) antagonist (68

242 e treatment of prostate cancer, radiolabeled gastrin-releasing peptide receptor (GRPr) antagonists ha

243 Because overexpression of the gastrin-releasing peptide receptor (GRPR) has been repor

244 MOR1D heterodimerizes with gastrin-releasing peptide receptor (GRPR) in the spinal

245 The overexpression of gastrin-releasing peptide receptor (GRPR) in various tum

246 Although our previous study suggested that gastrin-releasing peptide receptor (GRPR) is an itch-spe

247 The gastrin-releasing peptide receptor (GRPR) is found to be

248 The gastrin-releasing peptide receptor (GRPR) is overexpress

249 Gastrin-releasing peptide receptor (GRPR) is overexpress

250 The gastrin-releasing peptide receptor (GRPr) is overexpress

251 A growing body of evidence suggests that gastrin-releasing peptide receptor (GRPR) might be a val

252 Ablation of gastrin-releasing peptide receptor (GRPR) or GRPR neuron

253 Here we describe that the gastrin-releasing peptide receptor (GRPR) plays an impor

254 he Trpv1-Cre population, depends on CGRP and gastrin-releasing peptide receptor (GRPR) transmission b

255 -expression of Shh and BBS-cognate receptor (gastrin-releasing peptide receptor (GRPR)).

256 Gastrin-releasing peptide receptor (GRPR), a member of t

257 BBN) is a peptide with high affinity for the gastrin-releasing peptide receptor (GRPr), a receptor th

258 Its receptor, gastrin-releasing peptide receptor (GRPR), is expressed

259 Because expression of the gastrin-releasing peptide receptor (GRPR), somatostatin

260 peptide that binds with high affinity to the gastrin-releasing peptide receptor (GRPR), which is over

261 g very high selectivity and affinity for the gastrin-releasing peptide receptor (GRPr).

262 ic bombesin receptor antagonist that targets gastrin-releasing peptide receptor (GRPr).

263 is and to use bombesin analogs to target the gastrin-releasing peptide receptor for the diagnosis and

264 icals, such as prostate-specific membrane or gastrin-releasing peptide receptor ligands for the imagi

265 BON cells or BON cells stably expressing the gastrin-releasing peptide receptor treated with either p

266 between an agonist and an antagonist for the gastrin-releasing peptide receptor were found to have ex

267 ed independently of neurons that express the gastrin-releasing peptide receptor.

268 Gastrin-releasing peptide receptors (GRP-R) are upregula

269 Gastrin-releasing peptide receptors (GRPrs) are overexpr

270 Gastrin-releasing peptide receptors (GRPRs) expressed on

271 ded to understand the expression of PSMA and gastrin-releasing peptide receptors in different types o

272 ic bombesin receptor antagonist that targets gastrin-releasing peptide receptors.

273 ied two TMs (neuron-specific enolase and pro-gastrin-releasing peptide) that differentiate the risk o

274 g neurons respond to histamine and coexpress gastrin-releasing peptide, a peptide involved in itch se

275 uitary adenylate cyclase-activating peptide, gastrin-releasing peptide, and substance P is reviewed.

276 Gastrin, histamine, gastrin-releasing peptide, ghrelin, orexin, and glucocor

277 expressing cells, but a second neuropeptide, gastrin-releasing peptide, still induced strong response

278 ve agonist stimulated scratching behavior by gastrin-releasing peptide- and opioid-dependent mechanis

279 transient receptor potential subtype V1 and gastrin-releasing peptide.

280 e compounds demonstrated that antagonists of gastrin-releasing peptide/neuromedin B receptors (BB/BB)

281 of patients, demonstrating the potential of gastrin-releasing-peptide receptor imaging.

282 n upstream Sp1 binding GC box and downstream gastrin responsive elements.

283 The expression of CaR on gastrin-secreting G cells in the stomach and their share

284 al cilia on endocrine cells, which modulates gastrin secretion and gastric acidity.

285 These studies of nutrient-regulated G-cell gastrin secretion and growth provide definitive evidence

286 a role for endogenous GRP in meal-stimulated gastrin secretion in humans.

287 play a role in the perturbations in acid and gastrin secretion induced by H. pylori.

288 tion of FAK activity, is sufficient to block gastrin-stimulated paxillin phosphorylation, cell motili

289 Gastrin stimulates acid secretion directly and, more imp

290 We show here that gastrin stimulates Shh gene expression and acid-dependen

291 reas the gastrointestinal regulatory peptide gastrin stimulates the growth of neoplastic cells.

292 In gastric cancer cells, gastrin stimulation partially reversed the epigenetic si

293 lls, Rgnef forms a complex with FAK and upon gastrin stimulation, FAK translocates to newly-forming f

294 s that bombesin causes release of endogenous gastrin that activates sensory neurons located in the ga

295 Gastrin, through p38 activity, also enhanced HuR express

296 nker was used for crosslinking radio-labeled gastrins to membrane proteins from gastrin/PG responsive

297 Two-hour gastrin treatment, known to activate HDC gene expression

298 and particularly in neurons, elevated plasma gastrin, vacuolization in parietal cells, and retinal de

299 Gastrin was measured in blood, tissue, and cell cultures

300 les would also stimulate cell division - the gastrin would stimulate cell division of ECL cells while