ライフサイエンスコーパス: mechanically

1 nd carbyne species were investigated quantum mechanically.

2 tors-are also acid generators when activated mechanically.

3 ins, the force of translocation unfolds them mechanically.

4 tral bands of interest, and use it to create mechanically a conducting channel between two electrical

5 A gold standard for characterizing mechanically activated (MA) currents is via heterologous

6 of the AT1 R in arterioles and suggest that mechanically activated AT1 R generates diacylglycerol, w

7 Von Willebrand factor is proposed to be mechanically activated by flow, but the mechanism remain

8 Here, Rode et al. show that the mechanically activated cation channel Piezo1 is a molecu

9 ain-of-function phenotype with generation of mechanically activated currents that inactivate more slo

10 we provide an overview of recent advances in mechanically activated DDS.

11 and sensory neuron-specific ablation of the mechanically activated ion channel Piezo2 causes respira

12 ed into electrical signals via the gating of mechanically activated ion channels at sensory endings i

13 Piezos are mechanically activated ion channels that function as sen

14 Piezo1 and Piezo2 are mechanically activated ion channels that mediate touch p

15 rts it into green thiomerocyanine (TMC), the mechanically activated thiolate moiety of which undergoe

16 CAFs are thought to be more mechanically active but how this trait may alter the tum

17 tary cardiomyopathy and how titin protein is mechanically active in skeletal and cardiac myocytes.

18 e instabilities that are natural to occur in mechanically active media can be biochemically controlle

19 ntitative study that the pH actuation of the mechanically active rotaxane at the nanoscale influences

20 By using focus-tunable lenses, mechanically actuated displays, and mobile gaze-tracking

21 imeter distance from emphysematous voxels as mechanically affected lung (MAL).

22 conventional home machines for five new and mechanically aged jackets or sweaters: four from one nam

23 equator compresses the actomyosin network to mechanically align actin filaments.

24 particularly useful for polymers that form a mechanically alloyed morphology due to the high degree o

25 ence of "give" yield the same information as mechanically and Ca(2+)-induced force kinetics (k+Pi(1)

26 oaches, the entire system is treated quantum mechanically and neither fragmentation nor system-specif

27 Here, we introduce a new, mechanically and operationally simplistic magnetic manip

28 fluences this in vitro model of a blood clot mechanically and structurally on both microscopic and ma

29 enter data from the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS).

30 rating 5 variables (Interagency Registry for Mechanically Assisted Circulatory Support class, use of

31 h RVAD use included interagency registry for mechanically assisted circulatory support patient profil

32 AND Patients in the Interagency Registry for Mechanically Assisted Circulatory Support who underwent

33 thin the INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support) national regi

34 Using INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support), we sought to

35 ement mortality and Interagency Registry for Mechanically Assisted Circulatory Support-defined morbid

36 s demonstrate that segregating acentrics are mechanically associated with microtubules.

37 Mechanically, AURKA-mediated phosphorylation of LKB1 imp

38 ified HK relation, obtained from the quantum-mechanically based statistical rate theory (SRT) express

39 ic environment of the chalcogen atoms in the mechanically bonded rotaxane binding sites in organic an

40 nit and two triazolium anion-binding motifs, mechanically bonded with two smaller isophthalamide-cont

41 be impacted thermally by the hot bubbles and mechanically by fluid mechanical forces to transiently i

42 nd a linear free-energy relationship quantum mechanically calculated free energies of reaction and th

43 ath toward absolute thermometry with quantum mechanically calibrated ticks.

44 dagascar, consume the nutritionally poor and mechanically challenging culm or trunk of woody bamboos

45 anics to ecology as animals maneuver through mechanically challenging environments.

46 orts to develop high-throughput platforms to mechanically characterize single cells.

47 The mechanically comfortable sensor records high-fidelity el

48 s (pN)), suggesting that these molecules are mechanically compliant and perhaps act as entropic sprin

49 als of terephthalic acid are extraordinarily mechanically compliant and reversibly shape-shift betwee

50 limitation arises from the need for a soft, mechanically compliant interface, which enables conforma

51 we generated dense collagen type I sheets by mechanically compressing collagen hydrogels.

52 In this study, a biphasic mechanically-conditioned scaffold encapsulated with huma

53 zine (PTZ-) based radical junction using the mechanically controllable break junction technique.

54 which contribute to joint morphogenesis, are mechanically controlled and are significantly reduced in

55 Using the mechanically controlled break junction (MCBJ) technique,

56 experimental and computational study, using mechanically controlled break junction measurements and

57 cture of the main chain polymer results in a mechanically controlled sol-gel transition at the macros

58 Focal adhesions (FAs) mechanically couple the extracellular matrix to the dyna

59 Our results demonstrate that, in a mechanically coupled auditory system, specialization for

60 Actin filaments are mechanically coupled into a tight bundle by cross-linker

61 s to determine how the actin cytoskeleton is mechanically coupled to the surrounding matrix for prima

62 Machines and humans become mechanically coupled when lower limb amputees walk with

63 The mechanically-coupled ears of Ormia ochracea are speciali

64 CaM-binding site on the AQP0 cytosolic face, mechanically couples CaM to the pore-gating residues of

65 vironment for healing, but are surgically or mechanically debrided from the wound, causing additional

66 ich cells were cultured in biochemically and mechanically defined matrices to examine matrix-mediated

67 rradiation, thus allowing optical healing of mechanically degraded parts of the material.

68 of greater bamboo lemurs to persist on their mechanically demanding food source.

69 he oldest European inhabitants ingested more mechanically-demanding diets than later populations beca

70 t FHL2 phosphorylation by FAK is a critical, mechanically dependent step in signaling from soft matri

71 herapeutic shock waves have the potential to mechanically destroy diseased cells and/or increase cell

72 Here we report a thermally triggered mechanically destructive device, which is constructed wi

73 cal drawing, here, we used laser tweezers to mechanically dissect high-order DNA structures into two

74 ion constants (Kd = koff/kon), determined by mechanically dissociating the Fn.peptide complex at load

75 Nevertheless, mechanically distinct MT subsets provide a rich new sour

76 Electric eel-skin-inspired mechanically durable and super-stretchable nanogenerator

77 a greater incidence of spontaneous activity, mechanically evoked after-discharges, and/or increased r

78 e of LFP-related currents during episodes of mechanically-evoked SD.

79 a simple biophysical model in which CMs are mechanically excitable inclusions embedded within the ex

80 BP nanosheets were mechanically exfoliated and used as the sensing/conducti

81 ic study on the oxidation and passivation of mechanically exfoliated black phosphorus (BP).

82 ere we report a systematic infrared study of mechanically exfoliated few-layer black phosphorus, with

83 uch higher mobility and current density than mechanically exfoliated ML flakes due to the reduced con

84 igh crystallinity and comparable mobility to mechanically exfoliated samples, as confirmed by both at

85 st production of nanoelectronics on rigid or mechanically flexible substrates.

86 trical power sources that are biocompatible, mechanically flexible, and able to harness the chemical

87 This article describes the effect of mechanically fractionated flours from green bananas on t

88 evidence is desired, such as production of a mechanically gated conductance by pure TMCs.

89 on that reversibly reduce the sensitivity of mechanically gated currents in sensory neurons and silen

90 ear hair cells display at least two types of mechanically gated ion channel: normal mechanotransducer

91 It has been proposed that mechanically gated ion channels are of functional import

92 The sensitivity of Piezo mechanically gated ion channels is controlled by stomati

93 The question of how mechanically gated membrane channels open and close is n

94 hrough deflection of stereocilia that harbor mechanically-gated channels.

95 se particulate matter (P10-2.5) is primarily mechanically generated and includes crustal material, br

96 pulled to initiate a new neurite that can be mechanically guided to form new synapses at up to 0.8 mm

97 ity in both manually harvested olives and in mechanically harvested 'Manzanilla Cacerena' fruits for

98 flavor, were always higher in the oils from mechanically harvested fruits.

99 oring key labels or biomolecules to the gel, mechanically homogenizing the specimen, and then swellin

100 activated currents, but had no effect on the mechanically induced Ca(2+) influx.

101 Blocking voltage and calcium flux altered mechanically induced changes in protein concentration, w

102 nd k-Pi were similar to the rate constant of mechanically induced force redevelopment (kTR) and Ca(2+

103 We propose that mechanically induced HD growth involves the isotropic fl

104 (mTOR) signaling is necessary to generate a mechanically induced increase in skeletal muscle mass, b

105 Mechanically induced intercellular Ca(2+) waves rely on

106 We discovered that mechanically induced intercellular Ca(2+) waves require

107 l, and from non-related studies dealing with mechanically induced periodontal trauma, has been availa

108 al chest impacts (commotio cordis) can cause mechanically induced premature ventricular excitation (P

109 truction (UUO) and related cell models using mechanically induced pressure, oxidative stress, or high

110 restored substrate-binding capability due to mechanically induced removal of the auto-inhibitory regu

111 Using the high throughput MITOMI (mechanically induced trapping of molecular interactions)

112 depend on the lamin composition, may utilize mechanically induced, self-healing mechanisms that allow

113 we have developed a lab-on-a-chip capable of mechanically inducing circular cell-free areas within co

114 Areas of normal-appearing lung are mechanically influenced by emphysematous areas and this

115 agnetic microbeads to mechanically stimulate mechanically-inhibited CAFs showed partial rescue of vas

116 rtant for limiting the growth of S aureus on mechanically injured skin and caution that IL-23 and IL-

117 adducts was stronger in those sections from mechanically injured spinal cords.

118 chimera between a pore-forming domain of the mechanically insensitive ASIC1 channel and Piezo1.

119 ied as self-supporting layers since they are mechanically insufficiently strong.

120 This design enabled the MNs to mechanically interlock with soft tissues by selective di

121 loiting this property, the first examples of mechanically interlocked [2]rotaxanes containing ChB-don

122 In mechanically interlocked compounds, such as rotaxanes an

123 s in homo[2]catenane HC(*7+)-composed of two mechanically interlocked cyclobis(paraquat-p-phenylene)

124 ndent dynamic properties of the higher-order mechanically interlocked molecule.

125 At equilibrium, these Mechanically Interlocked Molecules (MIMs) undergo therma

126 Squaraine rotaxanes are mechanically interlocked molecules comprised of a dumbbe

127 how being able to template the formation of mechanically interlocked molecules has led to the design

128 nstrated here is an approach that integrates mechanically interlocked molecules into complex three-di

129 Mechanically interlocked molecules that change their con

130 As the macromolecular version of mechanically interlocked molecules, mechanically interlo

131 Mechanically interlocked molecules, owing to the particu

132 rsion of mechanically interlocked molecules, mechanically interlocked polymers are promising candidat

133 We develop an ex vivo tissue preparation to mechanically isolate radial glia endfeet from the soma,

134 ximal tensile stress in adjacent cells would mechanically isolate rapidly growing cells and limit the

135 artate and d-glutamate in individual neurons mechanically isolated from the CNS of the sea slug Aplys

136 , the resistance to stress in adjacent cells mechanically isolates rapidly growing cells, thus contri

137 Mechanically labile DNA duplexes presenting ligands are

138 Mechanically labile ligands dampen platelet activation,

139 w loading rates, alpha3D represents the most mechanically labile protein yet characterized by AFM.

140 nanoparticles that can image, localize, and mechanically load targeted proteins with high spatiotemp

141 erized pFn at bacterial poles formed part of mechanically loaded adhesion complexes, and pFn strength

142 odeling of the extracellular matrix (ECM) in mechanically loaded tissues are not yet clearly understo

143 on the active side of the MCs that have been mechanically manipulated to increase sensitivity.

144 Tissue explants were mechanically minced into 1 mm(3) pieces to minimize time

145 timulus to the brain, while outer hair cells mechanically modulate the stimulus through active feedba

146 Many of the mechanically morphing materials systems found in nature

147 The approach implements a quantum mechanically optimal strategy which under idealized cond

148 lar dynamics simulations informed by quantum-mechanically parametrized force fields, which identify t

149 Mechanically patterned (MP) extracellular matrix with al

150 work, we report the growth of h-BN films on mechanically polished cobalt (Co) foils using plasma-ass

151 Mechanically pre-deformed crystals taken over the therma

152 ngling or pushing are difficult to render in mechanically precise terms.

153 We demonstrate that COFs can be mechanically pressed into shaped objects having anisotro

154 These results suggest that maurocalcine mechanically prevented Ca(2+) from dissociating from its

155 adherent platelets use adhesion receptors to mechanically probe the adhesive substrate in their local

156 made possible by adding meat to the diet, by mechanically processing food using stone tools, or by co

157 ty for biofunctionalization, i.e., TiOx film mechanically protects the nanoparticles and induces chan

158 directional pulling forces by harnessing the mechanically purposeful motion of molecular switches in

159 However, how cells mechanically regulate robust mitotic rounding within pac

160 findings demonstrate that diapedesis can be mechanically regulated by the transmigrating leukocytes

161 re typically demonstrated in solution, where mechanically relevant motion is dissipated in the Browni

162 gel obtained from vacancy-driven gelation is mechanically resilient and can be used for a range of bi

163 urface of the 2D MoS2 nanoassemblies to form mechanically resilient and elastomeric nanocomposite hyd

164 with morphological mirror symmetry that are mechanically responsive to two opposing directions.

165 librium, maximally disordered, hyperuniform, mechanically rigid with infinite bulk and shear moduli,

166 Transparent and mechanically robust AEMs based on ionically cross-linked

167 These microstructures are mechanically robust and can act as templates to host met

168 The stretchable perovskite LEDs are mechanically robust and can be reversibly stretched up t

169 lated controls, may allow the engineering of mechanically robust biological replacements of native ti

170 blocks for the hierarchical construction of mechanically robust colloidosomes with a range of membra

171 icelles for the hierarchical construction of mechanically robust colloidosomes with a range of membra

172 ent a substantial step in the application of mechanically robust conformed and densified MOFs for hig

173 Devices are mechanically robust for 10,000 bending cycles.

174 oded short peptide tags functionalized via a mechanically robust Hydrazino-Pictet-Spengler ligation a

175 a design principle to generate lightweight, mechanically robust lattice structures based on triangul

176 c polymers has all been applied to form more mechanically robust networks.

177 We show the Photonic Needles to be mechanically robust when inserted into 2% agarose.

178 electronics and optoelectronic sensors in a mechanically robust, ultrathin format comparable in size

179 The uv1 neuroendocrine cells mechanically sense passage of eggs through the vulva and

180 ch we propose to be renamed "unconventional" mechanically sensitive channels, have some properties si

181 undle.SIGNIFICANCE STATEMENT Assembly of the mechanically sensitive hair bundle of sensory hair cells

182 hat expression of mammalian Tmc1 generates a mechanically sensitive ion channel in the plasma membran

183 f spatial perturbations in the properties of mechanically sensitive ion channels on the generation an

184 ansport of some of these components into the mechanically sensitive stereocilia of hair cells.

185 nd had Piezo2 mRNA and protein, as well as a mechanically-sensitive inward non-selective cation curre

186 Our findings suggest that mechanically-sensitive Piezo proteins contribute to the

187 V1 ion channel and reduces expression of the mechanically-sensitive Piezo2 channel; thermal threshold

188 er constituents are physically and therefore mechanically similar between species.

189 ndenter and found that insulitis made islets mechanically soft compared with controls.

190 ugh in vitro and in vivo studies using thin, mechanically soft systems that separately control as man

191 ent, we confirmed that increased HA leads to mechanically softer hydrogels, consistent with our model

192 othelia under vascular shear stress requires mechanically specialized interaction mechanisms, includi

193 ods have been developed to create porous and mechanically stable 3D scaffolds, the fabrication and co

194 be filled with a solvent, and thereby form a mechanically stable gel-like material.

195 udies reveal that BNNTs are structurally and mechanically stable materials in high temperature enviro

196 ccessful in-column thermal polymerization of mechanically stable poly(BuMA-co-EDMA) monoliths was ach

197 The fabricated sensor is mechanically stable, reusable, has a wide sensing range,

198 We also make mechanically stacked four-terminal tandem cells and obta

199 i-transparent cells are 12.3% efficient, and mechanically stacked tandems on silicon solar cells are

200 phorus (BP), hBN/BP/hBN heterostructures are mechanically stacked to devise high-efficiency THz photo

201 e stretch-induced membrane disruptions while mechanically stiffening the associated complexes under t

202 Finally, utilizing magnetic microbeads to mechanically stimulate mechanically-inhibited CAFs showe

203 ce for Rheb (iRhebKO) and TSC2 (iTSC2KO) and mechanically stimulated muscles from these mice with ecc

204 e sensor to recruit the fission machinery to mechanically strained sites.

205 istinctive ways by which molecular bonds are mechanically strengthened: catch bonds by constant force

206 cular level subfailure damage to collagen in mechanically stretched rat tail tendon fascicle.

207 that fine changes to molecular structures by mechanically stretching a single metal complex molecule

208 rrays (19x19 needles and 500mum height) were mechanically strong and were able to penetrate a skin si

209 iF coating serves as a chemically stable and mechanically strong interphase, which minimizes the corr

210 f Qilian, which we interpret as the top of a mechanically strong lower crust thrusting several tens o

211 re demonstrates multi-stimuli-responsive and mechanically strong properties.

212 s separation are usually deposited on porous mechanically strong supports with a hierarchical pore st

213 re, the stretchable triboelectric fibers are mechanically strong to be woven into a commercial textil

214 forcements, which presents opportunities for mechanically superior and "green" structural composites.

215 In addition, when studied in mechanically supported lipid membranes, a pronounced dis

216 rationally designed artificial SEI not only mechanically suppresses lithium dendrite formation but a

217 We further demonstrate that GFP can be mechanically switched between emissive and dark states.

218 l coordination stimulus, the tweezers can be mechanically switched from an open "W"-shaped conformati

219 The composites were mechanically tested in 4-point bending mode after aging

220 murs with and without simulated defects were mechanically tested under axial compression to failure.

221 Mechanically this thread presents a mixed solid-liquid b

222 The nucleus is linked mechanically to the extracellular matrix via multiple po

223 control, transforming brittle materials into mechanically tough blends.

224 r a three-day period, that the microgels are mechanically tractable, and that, for microscale cell as

225 high energy absorption, optical bandgaps and mechanically tunable acoustic bandgaps, high thermal ins

226 nto these fibres imparts the new property of mechanically tunable circularly polarized luminescence.

227 Using mechanically tunable polyacrylamide (PA) gels functional

228 encies because basilar membrane vibration is mechanically tuned to different frequencies along its le

229 molecule has been described that is able to mechanically twist a bound molecular guest, and molecula

230 )-mapping of all cells in the entire electro-mechanically uncoupled heart during the looping stage of

231 hylamine and histamine, but when Spy0125 was mechanically unfolded and subjected to forces of 50-350

232 structured metals via the stabilization of a mechanically unstable, negative stiffness state of a mar

233 However these alginate gels are mechanically unstable, not permitting their use as scaff

234 eld theory that suggest epsilon-plutonium is mechanically unstable.

235 Electrocardiogram recordings from 40 mechanically ventilated adult patients receiving sedativ

236 validity was supported by the separation of mechanically ventilated and nonventilated assessments.

237 r lubricants in preventing corneal damage in mechanically ventilated and sedated critically ill patie

238 All patients included in the study were mechanically ventilated and were receiving sedatives.

239 distress syndrome patients who were directly mechanically ventilated are similar in terms of lung epi

240 enic nerves were activated in synchrony with mechanically ventilated breaths.

241 sk of acute respiratory distress syndrome in mechanically ventilated burn patients, whereas acute res

242 Malnutrition is prevalent in mechanically ventilated children on admission to PICUs w

243 Mechanically ventilated children with acute respiratory

244 Four hundred nine mechanically ventilated children.

245 Nine anesthetized and mechanically ventilated closed-chest Landrace pigs (67 +

246 Clinical data from 16 mechanically ventilated critically ill obese patients we

247 were isolated from diaphragm biopsies of 36 mechanically ventilated critically ill patients and comp

248 Nonhypoxemic mechanically ventilated critically ill patients and heal

249 Twenty-four mechanically ventilated critically ill patients suitable

250 Almost one-third of mechanically ventilated critically ill patients were reh

251 Mechanically ventilated emergency department patients ex

252 Donors with COPD and donors who were mechanically ventilated exhibited lower cell counts (P <

253 with chronic critical illness (i.e., adults mechanically ventilated for >/=7 days and expected to re

254 tients (aged 18 years or older, who had been mechanically ventilated for <48 h, and were expected to

255 Six pigs were sedated and mechanically ventilated for 2.5 days with pacing on alte

256 domized adult ICU patients anticipated to be mechanically ventilated for greater than or equal to 48

257 dations were for acutely hospitalized adults mechanically ventilated for more than 24 hours to receiv

258 Donors with COPD and donors who were mechanically ventilated had reduced cell counts.

259 ned by collecting PM2.5 inside and outside a mechanically ventilated high school in the ultraindustri

260 We conducted a retrospective cohort study of mechanically ventilated ICU patients rehospitalized with

261 Of 26,947 mechanically ventilated ICU patients rehospitalized with

262 has not been established prospectively among mechanically ventilated ICU patients.

263 tion-analgesia quality and patient safety in mechanically ventilated ICU patients.

264 We prospectively enrolled 703 mechanically ventilated patients admitted to the emergen

265 Delirium is common in mechanically ventilated patients and is associated with

266 y of nonlinear imputation of PaO2/FIO2 among mechanically ventilated patients and understand what fac

267 lity for the Arabic CAM-ICU, overall and for mechanically ventilated patients assessed using Cohen's

268 We compared data from mechanically ventilated patients from 6 months before to

269 Twenty-four sedated, mechanically ventilated patients immediately prior to an

270 A total of 2,853 mechanically ventilated patients in ICU greater than or

271 Thirty mechanically ventilated patients in whom fluid administr

272 Early mobility in mechanically ventilated patients is safe, feasible, and

273 A major concern in mechanically ventilated patients is the risk of ventilat

274 In the contemporary ICU, mechanically ventilated patients may not have arterial b

275 All mechanically ventilated patients were potentially eligib

276 Forty-eight mechanically ventilated patients who were S. aureus posi

277 The cohort included 7,291 mechanically ventilated patients with 75,621 ventilator

278 This before-after study of mechanically ventilated patients with acute respiratory

279 rative randomized controlled trial involving mechanically ventilated patients with CS after AMI, rout

280 gm atrophy in a population of critically ill mechanically ventilated patients with ultrasound and to

281 ratory rate and equilibration time (teq) for mechanically ventilated patients without lung injury, it

282 ere also observed across subgroups; 100% for mechanically ventilated patients, 88% (60%-98%) and 79%

283 In mechanically ventilated patients, nonlinear imputation o

284 were excluded from SBT eligibility among all mechanically ventilated patients.

285 om 50 muL of airway secretions obtained from mechanically ventilated patients.

286 curacy of intravascular-volume assessment in mechanically ventilated patients.

287 e ventilator-induced lung injury observed in mechanically ventilated patients.

288 nsor in the carotid artery of anaesthetized, mechanically ventilated pigs, without lung injury.

289 Twelve mechanically ventilated pigs.

290 With the pigs anesthetized and mechanically ventilated, 40 mL/kg of blood was removed y

291 Anesthetized, mechanically ventilated, and surgically instrumented pig

292 of critically ill patients, 80% of whom were mechanically ventilated.

293 fants in whom CPAP failed were intubated and mechanically ventilated.

294 % (n = 218) were in the high group; 80% were mechanically ventilated.

295 ing the light-sheet and sectioning the heart mechanically, we establish a holistic strategy for 3-dim

296 Mechanically, we show that BAP1 represses metabolic stre

297 ey are typically fluidic in nature and often mechanically weak for applications such as drug delivery

298 ably, both SpaA and FimA initially refold to mechanically weaker intermediates that recover strength

299 wever, it is unclear how leukocytes interact mechanically with VECs to open the VEC junctions and mig

300 se hypotheses using a microfluidics assay to mechanically wound an epithelial monolayer in combinatio