ライフサイエンスコーパス: methyl ether

1 incorporated as a methyl ester rather than a methyl ether.

2 the biologically inactive derivative PMA-4-O-methyl ether.

3 trated by the synthesis of (S)-(+)-bakuchiol methyl ether.

4 ne followed by cyclodehydration gave cacalol methyl ether.

5 p synthesis of the tricyclic core of estrone methyl ether.

6 hesis of 1a, the C-glycoside analogue of PsA methyl ether.

7 d ortho hydroxylation of haloarenes and aryl methyl ethers.

8 ickel were undertaken with (diphosphine)aryl methyl ethers.

9 n conditions usually required for removal of methyl ethers.

10 er but failed in the removal of the two aryl methyl ethers.

11 yl alcohol, 0.038 microg L(-1) for tert-amyl methyl ether, 0.025 microg L(-1) for ethyl-tert-butyl et

12 nd 4-methoxy derivatives; 2-hydroxyestrone-3-methyl ether; 17beta-estradiol and its 2-hydroxy and 2-

13 -methoxy derivatives, and 2-hydroxyestrone-3-methyl ether; 17beta-estradiol and its 2-hydroxy, and 2-

14 profile resembled that of PsA (1) and PsA O-methyl ether (1b) when assayed for its anti-inflammatory

15 strone, 4-methoxyestrone, 2-hydroxyestrone-3-methyl ether, 2-methoxyestradiol, 4-methoxyestradiol, 2-

16 new reagent for the deprotection of aromatic methyl ethers, 2-(diethylamino)ethanethiol, is reported.

17 eal slightly higher GluN2B affinity than the methyl ethers 21.

18 tudies in rat brain preparations showed that methyl ethers (+)-21 (SNC 80) and (-)-25 exhibited stron

19 97%) along with a small amount (2.4%) of the methyl ether 22.

20 ortho-, meta- and para-Hydroxymethylaniline methyl ethers 3-5-OMe and acetyl derivatives 3-5-OAc wer

21 Deprotection of the methyl ether 39 finally gave 14-epiestone 40.

22 rides 3g and 4g as well as the corresponding methyl ethers 3b and 4b.

23 Although oxime O-methyl ether 4b lacks the traditional side chain hydroge

24 tification of miliacin (olean-18-en-3beta-ol methyl ether), a pentacyclic triterpene methyl ether tha

25 cetic acid terminated poly (ethylene glycol) methyl ether (aaPEG) onto the Thr residue of colistin.

26 including macromonomer poly(ethylene glycol) methyl ether acrylate (PEGA480), tert-butyl acrylate, an

27 on by sequential addition of ethylene glycol methyl ether acrylate and PEGA480 to a poly(methyl acryl

28 Poly(poly[ethylene glycol] methyl ether acrylate) (PPEGA480, DPn = 10, Mn,NMR = 490

29 Protein-resistant poly(ethylene glycol methyl ether acrylate-co-polyethylene glycol diacrylate)

30 gioselective deoxygenation of phloroglucinol methyl ether affords resorcinol.

31 of the configuration of the secondary allyl methyl ether against the alpha-alkoxy alkyllithium confi

32 ophilic cannabinoids, delta(8)-THC and its O-methyl ether analogue, Me-Delta(8)-THC using conventiona

33 nd derivative (8) contains a corresponding 6-methyl ether and a secondary amide of isonipecotic acid

34 On the other hand, tert-butyl methyl ether and anisole fail to form stable boron trich

35 to the discovery of the (alpha-L-alanyloxy)-methyl ether and hemifumarate derivatives of 1 which del

36 enin-2, vicenin-2, stellarin-2, lucenin-2 4'-methyl ether and scoparin), a 3-hydroxy-3-methylglutaryl

37 enin-2, vicenin-2, stellarin-2, lucenin-2 4'-methyl ether and scoparin), three flavonol derivatives (

38 Further studies with [2-(3)H]estradiol 3-methyl ether and with [2-(3)H]estradiol revealed a simil

39 Combinations of benzyl ether, naphthyl methyl ether, and biphenyl methyl ether repeat units wit

40 ertible N10-C11 carbinolamine, carbinolamine methyl ether, and imine forms of PBDs.

41 secondary alcohol to form the corresponding methyl ether, and MMAS-2 introduces a cis-cyclopropane i

42 dimethyl ether, poly(ethylene glycol) ethyl methyl ether, and poly(ethylene glycol) are found on the

43 ludes the use of benzyl methyl ethers, vinyl methyl ethers, and unbiased anisole derivatives, thus re

44 -2-ene-5-methoxy)alkanes, di(norborn-2-ene-5-methyl)ether, and 1,3-di(norborn-2-ene-5-methoxy)benzene

45 usions, the aromatic hydrogens of tyrosine O-methyl ether are photochemically inert, but become labil

46 rging mycotoxin" alternariol and alternariol-methyl ether arouse concern due to evidences of toxicity

47 Furthermore, use of a methyl ether as a stable protecting group for benzylic a

48 ria resulted in the discovery of tetrangulol methyl ether as an inhibitor of QR-2.

49 famates, esters, carbonates, carbamates, and methyl ethers as C-O-based electrophiles attached to the

50 Despite the formidable potential of aryl methyl ethers as coupling partners, the scarcity of meta

51 gh yields in either THF or CPME (cyclopentyl methyl ether) as solvent with heating to reflux.

52 than those of dA; however, introduction of a methyl ether at the 6 position of dG produced a noncleav

53 ns have been synthesized, including fraxinol methyl ether, ayapin, herniarin, xanthoxyletin, and allo

54 ol), derivatization of the 3-OH (cholesterol methyl ether, cholesteryl formate), and alteration of th

55 ndustin A derivatives to their corresponding methyl ethers consistently abolished their ability to in

56 A methyl ether corresponding to HSQ was detected when meth

57 es of benzyl-, phenylpropyl-, and biphenyl-4-methyl ether dendrons demonstrated biomimetic self-assem

58 Evaluation of the O-methyl ether derivative of 4 suggested that the 3-hydrox

59 ry with sorghum root extracts identified a 3-methyl ether derivative of the likely pentadecatrienyl r

60 in vitro antimicrobial profile of the tetra methyl ether derivative of vancomycin aglycon against va

61 A select series of methyl ether derivatives of vancomcyin aglycon were prep

62 n-containing Lewis bases, such as tert-butyl methyl ether, dioxane, anisole, ethyl acetate, beta-chlo

63 -hydroxy derivatives, and 2-hydroxyestrone-3-methyl ether; estradiol and its 2-, 4-methoxy and 2-, 16

64 In MeOH/MeCN, up to 28% of exo-2-norbornyl methyl ether formed at the expense of some of the norbor

65 ubstituted phenyl ring adorned with an extra methyl ether functional group, has also been synthesized

66 hilic aromatic substitution of benzazepine 3-methyl ethers gave 7-substituted analogs.

67 By using a substrate with a methyl ether in place of the Bzbr phenol, it was shown t

68 for the identification of 2-hydroxyestrone-3-methyl ether in urine obtained from both pre- and postme

69 e present a mild way of converting secondary methyl ethers into ketones using calcium hypochlorite in

70 er 3-(1H-imidazol-4-yl)propyl-(4-iodophenyl)-methyl ether (iodoproxyfan), which are strongly consiste

71 Normally, O-demethylation of this methyl ether is favored over benzofuran hydroxylation ba

72 with norbornylene in the presence of t-butyl methyl ether leads to formation of an iridium(I) Fischer

73 ain, a set of three adjacent bromines, and a methyl ether linkage on the phenyl ring.

74 es, 16-ketoestradiol, and 2-hydroxyestrone-3-methyl ether metabolites.

75 n polymerization (PP) of di(ethylene glycol) methyl ether methacrylate (MEO2MA), a thermo-responsive

76 quent in situ ATRP of oligo(ethylene glycol) methyl ether methacrylate (OEGMA) yielded a site-specifi

77 Polymerization of oligo(ethylene oxide) methyl ether methacrylate (OEOMA) in the presence of CuB

78 We prepared an oligo(ethylene glycol) (OEG) methyl ether methacrylate copolymer via RAFT polymerizat

79 EG-like polymer, poly(oligo(ethylene glycol) methyl ether methacrylate) [poly(OEGMA)], with low polyd

80 rthy sequence involving epoxidation of the O-methyl ether, methanolysis under mildly acidic condition

81 Direct generation of bis-methyl ether moieties from methoxymethyl ethers minimize

82 odehydration or photodeamination and deliver methyl ethers, most probably via quinone methides (QMs),

83 a blend formation with poly(ethylene glycol) methyl ether (mPEG) to prevent its leaching out from the

84 lvents, tetrahydrofuran, dioxane, tert-butyl methyl ether, n-pentane and dichloromethane.

85 -methoxycoumarin O-demethylation, tert-butyl methyl ether O-demethylation, and indole 3-hydroxylation

86 The formation of the methyl ether of (1R,2S,5R)-menthol was the only organic

87 es functionalised with poly(ethylene glycol) methyl ether of mean molecular weight 5000, provides a n

88 hromenes A (2), B (3), E (6), F (7), and the methyl ether of siccanochromene C (55).

89 nol, tert-butanol) and cleavage of sec-butyl-methyl ether on POM clusters with different central atom

90 Formation of the methyl ether product 22 suggests the involvement of a be

91 ah-Zap lignite, and a polystyrene-poly(vinyl methyl ether) (PS-PVME) polymer blend representing the m

92 ystyrene (dPS) grafted silica and poly(vinyl methyl ether) PVME matrix show that the sharp phase tran

93 l ether, naphthyl methyl ether, and biphenyl methyl ether repeat units with different alkyl carboxyla

94 Deuterium substitution of the methyl ether results in an inverse isotope effect on ben

95 utanesulfinyl amines with HCl in cyclopentyl methyl ether results in complete conversion to tert-buta

96 The finding that the binding of tropolone methyl ether (ring C of COL) induced a GTPase activity s

97 Retinyl methyl ether (RME) is known to prevent the development o

98 l transfer catalyst to provide a cyclopentyl methyl ether solution of ethyl tert-butanesulfinate with

99 oumaric acid, pinocembrin, and pinobanksin 5-methyl ether, specifically induce detoxification genes.

100 ethyl tert-butyl ether (ETBE), and tert-amyl methyl ether (TAME) by chemical oxidation (permanganate,

101 a-ol methyl ether), a pentacyclic triterpene methyl ether that is enriched in grains of common/broomc

102 zing the nanorods with poly(ethylene glycol) methyl ether thiol (PEG-thiol) prior to silica coating,

103 solvent free strategy to functionalize aryl methyl ethers through direct nucleophilic substitution o

104 the C-ring analogue of colchicine, tropolone methyl ether (TME), does not prevent this process.

105 A most striking result was that tropolone methyl ether (TME), which is ring C of COL, and which bi

106 ene, hydroxyhydroquinone, and phloroglucinol methyl ether to form pyrogallol, hydroquinone, and resor

107 ation of (PNP)Ir-CO and oxidation of t-butyl methyl ether to t-butyl formate via an iridium carbene.

108 cceptor, thermolysis of (PNP)IrH2 in t-butyl methyl ether under an atmosphere of CO2 also results in

109 recedented catalytic ipso-silylation of aryl methyl ethers under mild conditions and without recourse

110 wide scope, which includes the use of benzyl methyl ethers, vinyl methyl ethers, and unbiased anisole

111 S)-4'-(CH(3)O)-DADFT, 6] indicated that this methyl ether was a ligand with excellent iron-clearing e

112 Liquid-liquid extraction with tert-butyl methyl ether was used for plasma sample preparation, and

113 olecular C-H functionalization of a range of methyl ethers with high levels of site selectivity and e

114 Simple exchange of these methyl ethers with more labile functionalities disabled

115 es (styrene oxide, epichlorohydrin, glycidyl methyl ether) with CO2 under mild reaction conditions, d

116 Deprotection of this aryl methyl ether yielded cacalol.