ライフサイエンスコーパス: methyl radical

1 Me scission of the alkoxy radicals to form a methyl radical.

2 gmented to give the (2,2-diphenylcyclopropyl)methyl radical.

3 ore sensitive in detecting the production of methyl radical.

4 a pyramidal C(3v) anion to the planar D(3h) methyl radical.

5 a a mechanism that involves the formation of methyl radicals.

6 anticipated trends: 0 <or= F(C) <or= 0.3 for methyl radical, 0.4 for ethyl radical, 0.57 for n-propyl

7 on the reactivity of the 5-(2'-deoxyuridinyl)methyl radical (1) and 5-(2'-deoxycytidinyl)methyl radic

8 A 5-(2'-Deoxyuridinyl)methyl radical (1) was independently generated from thre

9 nyl radical (3) and 2-methylenecyclopentyl-1-methyl radical (1) were measured using the PTOC-thiol co

10 hotolysis of 2 generates 5-(2'-deoxyuridinyl)methyl radical (1), the reactive intermediate that resul

11 )methyl radical (1) and 5-(2'-deoxycytidinyl)methyl radical (2) was studied.

12 ne strongly lowers the activation energy for methyl radical addition.

13 ine coupling constants similar to the 4-POBN/methyl radical adduct found in aqueous solution.

14 ttacked by the hydroxyl radical to produce a methyl radical; administration of CsA with [(12)C]DMSO p

15 ection of two new stratospheric species, the methyl radical and diacetylene, gaseous species present

16 22 nm(-2)) that photolytically dissociate to methyl radicals and n-doped nanocrystals.

17 al preference for loss of aryl radicals over methyl radicals and that the selectivity for aryl vs met

18 ysis of CpW(CO)3Me has been shown to produce methyl radicals and to cleave DNA in a single-stranded m

19 dependent generation of 5-(2'-deoxycytidinyl)methyl radical, and our results demonstrate that this ra

20 Consistent with the methyl radical-based mechanism, there was no evidence fo

21 If a source of methyl radicals can be established, then the selective o

22 The loss of a methyl radical converts the CB(11)Me(12)(*) radical into

23 phoxide via homolytic bond cleavage leads to methyl radical formation and finally to methane in high

24 Methyl radical formation was further confirmed using [(1

25 using dimethyl sulfoxide (DMSO) demonstrated methyl radical formation, revealing the production of hy

26 Under anaerobic conditions, methyl radicals formed by fragmentation of the autocatal

27 thymidine methyl group, 5-(2'-deoxyuridinyl)methyl radical, forms interstrand cross-links with the o

28 Notably, a methyl radical, generated from peroxide, was confirmed b

29 e independently generated 5-(2'-deoxycytidyl)methyl radical (I) in single- and double-stranded oligod

30 N) spin-trapping experiments aimed to detect methyl radical in biological systems, the nitroxides for

31 is finding is consistent with an almost free methyl radical in the highest transition state.

32 h a single transition state by transfer of a methyl radical, in contrast to previously proposed react

33 drogen-atom reabstraction by an intermediate methyl radical is proposed.

34 adicals and that the selectivity for aryl vs methyl radical loss is dependent on the identity of the

35 hoxybenzene anion show peaks for consecutive methyl radical losses, a feature that establishes the 1,

36 density functional theory predictions of the methyl radical mechanism.

37 trapyrrole that promotes catalysis through a methyl radical/Ni(ii)-thiolate intermediate.

38 ught to involve either methyl-nickel(III) or methyl radical/Ni(II)-thiolate intermediates.

39 f thymine and 5-methylcytosine to give the 5-methyl radical of the pyrimidine bases.

40 The methyl radical produced by the hydroxyl radical represen

41 o involve a one-electron transfer, producing methyl radicals that incorporated into the GAC.

42 s on time scales ranging from <or=0.5 ns for methyl radical to 2.3 ns for adenosyl, the largest radic

43 dical is proposed to subsequently transfer a methyl radical to IB, thus launching the formation of b-

44 ith the (*)OH scavenger Me(2)SO, which forms methyl radical upon reacting with (*)OH.

45 Methyl radicals were detected during ultrasonication by

46 Hydroxyl radical oxidizes DMSO to methyl radical, which forms relatively stable nitroxides

47 nitase and xanthine/xanthine oxidase yielded methyl radical, which was detected by ESR spin trapping.