ライフサイエンスコーパス: methylene

1 hosphate modifications (thio, borano, imido, methylene).

2 e, Apiol, 1,6-Cyclodecodiene, and 1-methyl-5-methylene.

3 and increased the disorder of the acyl chain methylenes.

4 with borane, reducing the carbonyl groups to methylenes.

5 xo-dig-cycloisomerization of enynes and keto-methylenes.

6 lic ketene acetals, specifically 5,6-benzo-2-methylene-1,3-dioxepane (BMDO), results in well-defined,

7 olymers can uniquely be copolymerized with 2-methylene-1,3-dioxepane (MDO) to generate polymers in wh

8 -Methyl-1alpha,25-(OH)2D3, both epimers of 9-methylene-10,19-dihydro-1alpha,25-(OH)2D3 as well as the

9 imer, were found to be almost as active as 2-methylene-19-nor-(20S)-1alpha,25-dihydroxyvitamin D3 (2M

10 eover, 9alpha-methyl-1alpha,25-(OH)2D3 and 9-methylene-19-nor-1alpha,25-(OH)2D3 showed some in vitro

11 vitamin with the "reversed" triene system, 9-methylene-19-nor-1alpha,25-(OH)2D3, were obtained from t

12 ig cyclization onto the alkyne, leading to 3-methylene-2,3-dihydrobenzofuran derivatives.

13 tor ITCC (3,9-bis(4-(1,1-dicyanomethylene)-3-methylene-2-oxo-cyclopenta[b]thiophen)-5,5,11 ,11-tetrak

14 ne-derivative (aurin; 4-[bis(p-hydroxyphenyl)methylene]-2,5-cyclohexadien-1-one) was identified as an

15 ons, namely Wittig reactions, reactions with methylene active compounds, formation of amines, amides,

16 ion of methyl coumalate with a wide range of methylene active compounds, such as keto-esters or keto-

17 tructures of SMPDL3A with AMP and alpha,beta-methylene ADP (AMPCP) reveal that the substrate binding

18 Inhibition of CD73 by alpha,beta-methylene ADP (AOPCP) in the whole CB preparation in vit

19 The eN inhibitor alpha,beta-methylene-ADP (AOPCP, adenosine-5'-O-[(phosphonomethyl)p

20 CD73 mRNA, and alphabeta-methylene-ADP-inhibitable ecto-AMPase activity were elev

21 An ADPR analog, alpha-beta-methylene-ADPR (AMPCPR), was shown to be entirely resist

22 Substitution at the level of the side chain methylene afforded compounds targeting specifically and

23 tibodies has been developed and involves the methylene alkoxy carbamate (MAC) self-immolative unit.

24 tes by using bromocrotonate as the activated methylene alkylating agent.

25 -bis(diethylamino)-2-{[(1E)-(4-ethoxyphenyl) methylene] amino}spiro[isoindole-1,9'-xanthen]-3(2H)-one

26 All four 2-methylene analogues of the native hormone were character

27 .005 and 0.5-0.06 mug/mL for the amidine and methylene analogues, respectively) and likely benefit fr

28 eported for a cyclohexane featuring opposing methylene and a vinylidene fragments.

29 le to directly functionalize allylic methyl, methylene and methine carbons in a catalytic manner is a

30 he ring test spectral ensemble that contains methylene and methyl peaks (1.4-0.6 ppm) showed that 97.

31 nation occurring in each pathway at both the methylene and methyl positions of ethanol has been inves

32 two trimethylstannyl units, one linked by a methylene and the other by an ethylene group.

33 retina, the P2X1 receptor agonist alpha,beta-methylene ATP (300 nm) evoked sustained vasoconstriction

34 The P2X receptor agonist alpha,beta-methylene ATP (alpha,beta-meATP; 10 muM) evoked rapidly

35 es to intra-arterial injection of alpha,beta-methylene ATP or lactic acid.

36 esic markers capsaicin, AITC and alpha, beta-methylene ATP.

37 ] ring expansion to yield highly substituted methylene azetidines with excellent regio- and stereosel

38 where the unique strain and structure of the methylene aziridine promotes a ring-opening/ring-closing

39 hodium-bound carbenes with strained bicyclic methylene aziridines results in a formal [3+1] ring expa

40 ethod for Pd(II)-catalyzed cross-coupling of methylene beta-C(sp(3))-H bonds in cyclobutanecarboxylic

41 alpha-methyl groups over those of the alpha-methylene, beta- or gamma-methyl groups.

42 NI through free radical polymerization using methylene bis-acrylamide, and ammonium persulphate as th

43 entified three dibenzoates [1,3-phenylenebis(methylene) bis(3-fluoro-4-hydroxybenzoate) (RA-2), 1,2-p

44 -4-hydroxybenzoate) (RA-2), 1,2-phenylenebis(methylene) bis(3-fluoro-4-hydroxybenzoate), and 1,4-phen

45 oro-4-hydroxybenzoate), and 1,4-phenylenebis(methylene) bis(3-fluoro-4-hydroxybenzoate)] with inhibit

46 salts (3-5), and 1,1'-(pyridine-2,6-diylbis(methylene))bis(3-(4-(phenyl ethynyl)benzyl)-1H-benzo[d]i

47 rbene) ligand bis(N-Dipp-imidazole-2-ylidene)methylene (bisNHC, 1) affords [(bisNHC)AlBr2](+)Br(-) (2

48 Methylene blue (4 muM) irradiated with red light (660 nm

49 S-FF in dispersive solid phase extraction of methylene blue (as a cationic dye model) in water and sh

50 ecule with its cavities matching the size of methylene blue (MB(+)), a versatile organic molecule use

51 NA biosensor is developed based on employing methylene blue (MB) as a redox indicator.

52 Using methylene blue (MB) as an electrochemical probe and diff

53 us DNA sequence of Dengue virus (DENV) using methylene blue (MB) as an intercalating agent.

54 otocatalytic effect was also confirmed using methylene blue (MB) dye degradation under natural sunlig

55 Methylene Blue (MB) forms an inclusion complex with Grp-

56 valuated as an inexpensive sorbent to remove methylene blue (MB) from aqueous solution.

57 Methylene blue (MB) has been shown to be safe and effect

58 gate the influence of nanostructuring on DNA-methylene blue (MB) interactions and their application t

59 transfer (ET) between the gold electrode and methylene blue (MB) label conjugated to a double-strande

60 Then, thiolated capture probe (CP) with methylene blue (MB) labeled at 5' end is modified on the

61 ragment of dimebon and phenothiazine core of methylene blue (MB) linked by 1-oxo- and 2-hydroxypropyl

62 -VEGF165 aptamers, resulted in desorption of methylene blue (MB) probe from aptamer and its release i

63 ers were labeled with anthraquinone (AQ) and methylene blue (MB) redox reporters respectively.

64 ocessed graphene oxide nanoribbon (GONR) for methylene blue (MB) sensing.

65 Methylene blue (MB) was employed as electrochemical indi

66 tabilized gold nanoparticles (PLA-AuNPs) and methylene blue (MB) was employed as the redox indicator

67 applied in an adsorption column, to pretreat methylene blue (MB) wastewater with high concentration (

68 ne show a highly sensitive SERS detection of methylene blue (MB) with calculated enhancement factors

69 ed by interaction of anionic mediator, i.e., methylene blue (MB) with free guanine (3'G) of ssDNA.

70 tion in current, generated by interaction of methylene blue (MB) with free guanine (3'G) of ssDNA.

71 ased on these findings, we hypothesized that methylene blue (MB), a mitochondria-permeant redox-activ

72 Methylene blue (MB), a phenothiazine dye that crosses th

73 Methylene blue (MB), a traditional mitochondrial-targeti

74 a unique competitive detection scheme using methylene blue (MB), hydrazine and platinum nanoparticle

75 latin sensor fabricated with a thiolated and methylene blue (MB)-modified oligo-adenine (A)-guanine (

76 formation of these complexes rigidifies the methylene blue (MB)-modified oligoadenine probes, result

77 The methylene blue (MB)-modified probe assumes a linear unst

78 ction between Cr(VI) and surface-immobilized methylene blue (MB).

79 ne reductase inhibitor and redox cycler drug methylene blue (MB).

80 catalytic reduction of H2O2 by oxidation of methylene blue (MB).

81 ry after extinction training by low-dose USP methylene blue (MB).

82 pain-gel with a red-light absorbing pigment (methylene blue - MB) to mediate photodynamic therapy (PD

83 n used to treat malaria (quinacrine [QC] and methylene blue [MB]) or to study P. falciparum (acridine

84 s xylem flux toward the bud, as evidenced by Methylene Blue accumulation in the bud after CK treatmen

85 the memory-enhancing effects of posttraining methylene blue administration on retention of fear extin

86 determine the affinity constant, KD, of the methylene blue Affimer to be comparable to that of antib

87 grade silicone incorporating crystal violet, methylene blue and 2 nm gold nanoparticles.

88 s demonstrate a nearly 100% removal rate for methylene blue and an impressively high removal rate for

89 toring of the photocatalytic degradations of methylene blue and methyl orange under different flow ra

90 analogous to the Calvin cycle) between leuco-methylene blue and the onium salt oxidant that is respon

91 h to highlight the exceptional properties of methylene blue as a redox reporter in such applications

92 ectrochemical detection of cholesterol using Methylene Blue as redox indicator.

93 ndicates that a PEG-based peptide, employing methylene blue as redox reporter, and deposited on an el

94 ay of simultaneously using two redox probes: Methylene blue as the reporter of the conformational cha

95 Conclusion Low-dose methylene blue can increase functional MR imaging activi

96 ion and vesicle degradation as a function of methylene blue concentration follows a diffusion law in

97 ians use radio-labeled sulfur colloid and/or methylene blue dye to identify the SLN, which is most li

98 rparts for the photocatalytic degradation of methylene blue dye under visible-light irradiation.

99 ely detect SLNs based on the accumulation of methylene blue dye.

100 Methylene blue enhances memory and the retention of fear

101 Double strand specific intercalator methylene blue in combination with [Fe(CN)6](3-) is used

102 issue expansion effects and a visual lack of methylene blue in the fibroids.

103 ral correlates of the oral administration of methylene blue in the healthy human brain.

104 hat underwent LN excision had no evidence of methylene blue in the iliac nodes; mice without surgical

105 nzthiazoline-6-sulfonic acid), dopamine, and methylene blue in the presence of O2.

106 r catalytic activity toward the reduction of methylene blue in the presence of sodium borohydride.

107 Results Administration of methylene blue increased response in the bilateral insul

108 5), or no intervention (n = 5), followed by methylene blue injection.

109 on alters the accessibility of Cr(VI) to the methylene blue label on the surface-immobilized DNA prob

110 f two DNA adaptor strands modified with four methylene blue molecules and electrocatalysis using gluc

111 g the retention of the ion-pairs formed with Methylene Blue on the muMNPC.

112 and 1 hour after administration of low-dose methylene blue or a placebo.

113 Some fibroids exhibited regions with partial methylene blue penetration into the tumor environment.

114 responsible for regeneration of the organic methylene blue photocatalyst.

115 f photocatalytic reactions in an Ag nanocube-methylene blue plasmonic system.

116 fare worse at the follow-up if they received methylene blue posttraining.

117 on's r=-0.68 or beyond) between collagen and methylene blue staining.

118 ofabrication technologies, and modified with methylene blue tagged aptamer using standard gold thiol

119 r solution containing blood vessel stain and methylene blue to analyze intratumoral transport.

120 on and subsequently promote the reduction of methylene blue to its colorless leuco form.

121 Mice were dissected to determine whether methylene blue traveled to the iliac LN.

122 on or with sham LN excision consistently had methylene blue visible in the ipsilateral iliac nodes.

123 lysis of variance was performed with a drug (methylene blue vs placebo) and time (before vs after adm

124 As methylene blue was able to passively diffuse into fibroi

125 Methylene blue was also associated with a 7% increase in

126 Two milliliter of methylene blue were instilled above the cuff to quantify

127 Among Gram-negative bacteria, only methylene blue with E. coli K12 and rose bengal with C.

128 eading to an improved electronic exchange of methylene blue with the electrode surface due to the red

129 ucts with DNA, a duplex intercalating agent (methylene blue), and a cytotoxic metal ion (Hg(II)) whic

130 n Toray paper as support and a layer of poly(methylene blue)/tetrabutylammonium bromide/Nafion and gl

131 We also demonstrate that methylene blue, a reported tau aggregation inhibitor, mo

132 ng electrochemical biosensors, ferrocene and methylene blue, along with the effect of changing both t

133 lectrodes modified with polythymine, bearing methylene blue, as redox probe, in 3' position.

134 blocked by the methemoglobin reducing agent methylene blue, haptoglobin, or the heme-binding protein

135 uced plasma sound source) to deliver agents (methylene blue, MB, in PBS) into bovine AC.

136 We used three synthetic photosensitizers (methylene blue, rose bengal, and nitrite) and two model

137 amely 9,10-anthraquinone-1,5-disulfonate and methylene blue, were used as surrogates for dissolved or

138 Doing so we find that the performance of methylene blue-based, thiol-on-gold sensors is unmatched

139 tuberculosis and Escherichia coli) by using methylene blue-labeled structure-switching DNA stem-loop

140 Photooxidation of methylene blue-NP41-bound nerves, followed by biotin hyd

141 Methylene blue-tagged peptides combined with a polyethyl

142 tion of small organic target compounds, here methylene blue.

143 one, chloroquine, proguanil, cycloguanil and methylene blue.

144 Pt(IV) center of SAT and surface-immobilized methylene blue.

145 nts up to 3.4 x 10(3) for the probe molecule methylene blue.

146 traction in TAA by DPPH was located on -CH2- methylene bridge because the corresponding radical was m

147 Methylene bridge formation has profound effects on the p

148 of fluorenes having an enamine moiety at C-9 methylene bridge is developed from N-sulfonyl-4-biaryl-1

149 v) transition state (2) for inversion of the methylene bridge of 1 is antiaromatic and supports a two

150 presence of CO2 or formaldehyde form mutual, methylene-bridged cross-links between Lys(158) and Cys(2

151 The bowl-shaped structure of methylene-bridged indenocorannulene was verified by X-ra

152 Fluorenes and methylene-bridged polyarenes were easily and efficiently

153 s and supramolecular properties of the first methylene-bridged propanediurea-based dimers are describ

154 mR (EcFrmR) protein reveals the formation of methylene bridges that link adjacent Pro2 and Cys35 resi

155 thoxyphenyl moiety with a sulfur, ketone, or methylene bridging group at position 3 of the indole and

156 Selective bromination of gamma-methylene C(sp(3) )-H bonds of aliphatic amides and delt

157 p(3) )-H bonds of aliphatic amides and delta-methylene C(sp(3) )-H bonds of nosyl-protected alkyl ami

158 The beta-methylene C(sp(3) )-H bonds of various carbocyclic rings

159 ctive alkoxycarbonylation of both methyl and methylene C(sp(3))-H bonds with alkyl chloroformates thr

160 However, methylene C(sp(3))-H carbonylation remains a great chall

161 vors the C-H bonds of methyl groups over the methylene C-H bonds and tolerates various functional gro

162 c enantioselective functionalization of beta-methylene C-H bonds in aliphatic amides.

163 II)-catalyzed C-H carbonylation reactions of methylene C-H bonds in secondary aliphatic amines lead t

164 opment of methods to functionalize the alpha-methylene C-H bonds of these systems enantioselectively

165 ligands for the enantioselective coupling of methylene C-H bonds with aryl boronic acids.

166 and applied to the oxidation of unactivated methylene C-H bonds.

167 sing reactions, where E-butene serves as the methylene capping agent, are provided.

168 In situ methylene capping is introduced as a practical and broad

169 The in situ methylene capping strategy was used with the same Ru cat

170 vity because it generates extremely reactive methylene carbene.

171 2'-Fluoro-6'-methylene carbocyclic adenosine (FMCA) is a potent and s

172 e presence of TBAI/TBHP, esters possessing a methylene carbon alpha-to oxygen with benzylamines provi

173 sertion into prochiral C-H bonds on a single methylene carbon center.

174 to a tRNA(Glu)substrate through the terminal methylene carbon of a formerly methylcysteinyl residue a

175 iral carbon-hydrogen (C-H) bonds on a single methylene carbon via asymmetric metal insertion remains

176 state photoisomerization that transposes the methylene carbon.

177 Robenidine, 1 (2,2'-bis[(4-chlorophenyl)methylene]carbonimidic dihydrazide), was active against

178 1, 27 (2,2'-bis{[4-(1,1-dimethylethyl)phenyl]methylene}carbonimidic dihydrazide), and 69 (2,2'-bis[1-

179 bbon-shaped nanostructures, whereas the nine methylene CAs assembled into long nanofibers without cry

180 > carbonyl (CO) approximately ester (COO) > methylene (CH2).

181 ng arginine and lysine analogues with varied methylene chains as well as all-d-isomers were synthesiz

182 A similar diphosphine with longer methylene chains, P((CH2)18)3P, is equally effective.

183 mixture of hexafluoro-2-propanol (HFIP) and methylene chloride (DCM) is described.

184 Active methylene compounds react with in situ generated nonstab

185 When other active methylene compounds were subjected to this domino reacti

186 for the two bonds departing from the central methylene considerably affects the binding of compound 1

187 s, as well as amorphous and crystalline poly(methylene)-containing components were enriched using neu

188 oth intra- and intermolecular aldehyde alpha-methylene coupling with olefins to construct both cyclic

189 o Cp*(Cl)Ti(N(t)Bu)(NC5H5) (10) and an alpha-methylene cyclopent-3-enimine (11).

190 carbocyclic key intermediate, D-2'-fluoro-6'-methylene cyclopentanol 14, has been developed from diaz

191 en isotope ratios of the methyl [(D/H)I] and methylene [(D/H)II] groups in ethanol can be used as geo

192 lpha-Methylene-gamma-butyrolactone and alpha-methylene-delta-valerolactone undergo Pd-catalyzed Matsu

193 ty (kcat/Km) for asparagine despite only one methylene difference in length.

194 ine/isocyanate metathesis reaction with 4,4'-methylene diphenyl diisocyanate (4,4'-MDI) circumvents h

195 trial grade MDA, multimeric MDA species, and methylene diphenyl diisocyanate (MDI) mixtures.

196 MDA is a precursor to methylene diphenyl diisocyanate (MDI), a hard block comp

197 5 procedures performed on children: (99m)Tc-methylene diphosphate (MDP) bone scans, (99m)Tc-mercapto

198 ific CD73 inhibitor (adenosine 5'-alpha,beta-methylene-diphosphate) enhanced the microbicidal M1 subs

199 nventional imaging (CT or MRI, and a (99m)Tc-methylene diphosphonate bone scan) before enrollment.

200 In an exploratory analysis, paired (99m)Tc-methylene diphosphonate bone scans ((99m)Tc-BS) were ava

201 ncer patients after a single 600-MBq (99m)Tc-methylene diphosphonate injection.

202 ons of electron-rich aldehydes and activated methylene donors.

203 C5 is the largest to date for a nonanomeric methylene due to an unprecedented through-space n --> si

204 phenylene) bipyridin-1-ium-1,4-phenylene-bis(methylene)) (ExBox(4+)) to form both the ExBox(3+*) and

205 te that the enzyme's reduced flavin relays a methylene from the folate carrier to the nucleotide acce

206 The 2-methylene-furan-3-one reductase or Fragaria x ananassa E

207 alpha-Methylene-gamma-butyrolactone (MBL), a naturally occurri

208 Design, synthesis, and evaluation of alpha-methylene-gamma-butyrolactone analogues and their evalua

209 alpha-Methylene-gamma-butyrolactone and alpha-methylene-delta-

210 est that an isatin-derived spirocyclic alpha-methylene-gamma-butyrolactone is a suitable core for opt

211 r the synthesis of an optically active alpha-methylene-gamma-lactone from p-chlorostyrene has been de

212 The buckypaper anode consisted of poly(methylene green) and a hydrogel matrix containing lactat

213 Intramolecular exchange of the methylene group bound to the metal within the cyclopenta

214 ent functionalization of the unreactive beta-methylene group in an unprecedented tandem fashion and u

215 nd orthogonal specificities even if only one methylene group is exchanged between the polymer backbon

216 olecule in the vitamin D receptor when the 2-methylene group is present may provide new insight into

217 demonstrate the vibrational spectroscopy of methylene group of adsorbed sub-monolayer cetrimonium br

218 However, in the 20R series, a 2-methylene group was required for high bone mobilizing ac

219 Second, for the methylene group, a significant apparent kinetic isotope

220 ethyl group are more pronounced than for the methylene group.

221 m alkanes were prepared, where the number of methylene groups between the ammonium groups ranges from

222 Methyl as well as cyclic and acyclic methylene groups can be activated.

223 pendant functions as similar as carbonyl or methylene groups in a complex assembly process.

224 sive regioselectivity in the presence of two methylene groups in different steric environments.

225 fatty acids in intramyocellular lipids, and methylene groups in extramyocellular lipids were found.

226 on of the four oxygens in TOTMB for the four methylene groups in TMB is very unusual, since the singl

227 The methylene groups of R provide an experimental probe of t

228 onds, which may by separated by one to three methylene groups.

229 The functionalized activated methylene halides employed in these reactions for the sy

230 thiolate salts with functionalized activated methylene halides.

231 y, the introduction of a methyl group at the methylene hinge connecting the 6-amino-9H-purin-9-yl pen

232 A, the dimethyl analogue 2 and four isomeric methylene homologues (including the natural product itse

233 keleton is more difficult because one of the methylene hydrogen atoms (Hb) has its BDE lowering withi

234 es F(-) through its partially positive gamma-methylene in mimicry of phenylalanine's quadrupolar inte

235 Fragmentation allowed us to quantify the methylene incorporation at specific sites.

236 tructures of eight alkyl benzenes, in single-methylene increases from benzene to n-hexylbenzene, boun

237 in the discovery of (E)-3-((1H-indazol-6-yl)methylene)indolin-2-ones, which are superseded by the bi

238 K4 inhibitors yielded (E)-3-((1Hindazol-6-yl)methylene)indolin-2-ones, which were superseded by the b

239 boxylic acid analogs containing an exocyclic methylene instead of an epoxide, indicating that the FMO

240 On the other hand, 3-[(alkoxycarbonyl)methylene]isobenzofuran-1(3H)imines were selectively obt

241 s a key hydroxy-directed CH olefination of 1-methylene isochroman with an alpha,beta-unsaturated keto

242 led to the formation of 3-[(dialkylcarbamoyl)methylene]isoindolin-1-ones through the intermediate for

243 sation of readily available (het)aryl active methylene ketones with (het)aryl dithioesters followed b

244 (3H)-ones, as these substrates are exocyclic methylene lactamyl Michael acceptors.

245 entenolides, whereas the five-membered alpha-methylene lactone reacts to mixtures of regioisomers wit

246 onditions for Matsuda-Heck arylations of exo-methylene lactones were eventually applied to the synthe

247 the 2'-position of arabinouridine through a methylene linker are conveniently prepared and incorpora

248 uthenium(II) complexes bridged by a flexible methylene linker have received considerable interest as

249 ly modulated by hydroxyl substitution on the methylene linker, where the R-hydroxy isomer has a 60-fo

250 ained from diethyl 2-[((3-methylphenyl)amino)methylene]malonate.

251 ]pyrrol-2-yl)benzo[c][1,2,5 ]thiadiazol-4-yl)methylene)malononitrile leads to an increased open-circu

252 ]pyrrol-2-yl)benzo[c][1,2,5 ]thiadiazol-4-yl)methylene)malononitrile.

253 ster linkage between Glu6 and the nascent C4 methylene moiety of DMIA.

254 The benzylic methylene moiety was found to be the source of the aroyl

255 has been replaced by the cyano(4-nitrophenyl)methylene moiety.

256 diazepine ternary center and the side chain methylene moiety.

257 ed for the imidazolium C(2)-CH3 protons, the methylene N-CH2 protons, and the inner aromatic proton o

258 ionic macrocycle which contains two N,N'-bis(methylene)naphthalenediimide units inserted in between t

259 e more in favor of the methyl group than the methylene of the pentyl chain, in excellent agreement wi

260 n of protected 2,3-dideoxy-2-fluoro-2,3-endo-methylene-pentofuranoses from d-glyceraldehyde and 2,3-d

261 -dideoxy-2-fluoro-3-C-hydroxymethyl-2,3-endo-methylene-pentofuranoses from d-isoascorbic acid, via Si

262 scaffold for synthetic elaboration at the 2-methylene position thereby affording extended oxazoles.

263 alytic carbene transformations from oxidized methylene precursors.

264 , ammonium (preserving positive charge), and methylene (preserving neither pi-accepting capabilities

265 ed (1)H resonances originating from the four methylene protons of the azadithiolate ligand in the [2F

266 roposed for these enzymes is the attack of a methylene radical, derived from a methylcysteine residue

267 (2))-H and one C(sp(3))-H bond of the active methylene residue.

268 nal monomers are often dominated by the long methylene sequences of the repeat units in their solid-s

269 he stereoelectronic properties of the sulfur-methylene sigma bonds that terminate the molecule.

270 lopropanation of alkenes with CH2 Cl2 as the methylene source.

271 A flexible 3-carbon methylene spacer between the exo N atom of the sugar moi

272 ate of CH3ReO3/Al2O3 is a distribution of mu-methylene species formed by the activation of the C-H bo

273 xtensive series of DFT calculations, that mu-methylene structures (Al-CH2-ReO3-Al) containing a Re ho

274 ic alcohol derivatives possessing a terminal methylene substituent.

275 tom-'substituted' NTPs, we elucidate how the methylene substitution in the pyrophosphate leaving grou

276 bonds in U:dT recovers a strong response to methylene substitution of UTP.

277 Intriguingly, the effect of the beta,gamma-methylene substitution on the non-cognate UTP/dT scaffol

278 E)-2-{[(1-tert-butoxycarbonyl)-1H-indol-3-yl]methylene}succinate and (R)-2,2,5,5-tetramethyl-1,3-diox

279 the convenient use of dimethyl malonate as a methylene synthon.

280 nd does not evolve spontaneously to a stable methylene tautomer.

281 rial one-carbon metabolism by suppression of methylene tetrahydrofolate dehydrogenase/cyclohydrolase.

282 We assessed a causal relationship of WMH to methylene tetrahydrofolate reductase (MTHFR).

283 mmon polymorphisms, the c. 1298A > C, of the methylene-tetrahydrofolate reductase (MTHFR) gene, an en

284 for generating CH3-THF in organisms without methylene-tetrahydrofolate reductase.

285 For linker lengths up to seven methylenes, the CAs were found to pack into 2D crystalli

286 -(4-bromophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)methylene)thiazolidine-2,4- dione (2), a thiazolidine-2,

287 (Z)-2-(nitro((E)-p-substitutedphenyldiazenyl)methylene)thiazolidines in xylene and dimethoxyethane un

288 own to be a reactive and versatile source of methylene to create new C-N but also C-O and C-C bonds.

289 intramolecular sulfamidation at the benzylic methylene to give N-arylsuflonyl-1-arylisoindolinones, w

290 s N(1),N(1'),N(1'')-(benzene-1,3,5-triyltris(methylene))tris(N(4)-(4-(methylamino)b utyl)butane-1,4-d

291 Surprisingly, homologation with a single methylene unit between the oxadiazole and heterocyclic r

292 3, corresponding to the number of catenated methylene units between imino nitrogen atoms).

293 hed by systematic variation of the number of methylene units between the double bond and the trifluor

294 fatty acid chains differing in length by two methylene units, but analysis of the reported data sugge

295 s of 2a, 2b, and 2c incorporated 3, 6, and 9 methylene units, respectively.

296 eoxy-2'-fluoro-3'-C-hydroxymethyl-2',3'-endo-methylene-uridine by X-ray crystallography yielded the p

297 indicating the dominance of antisymmetric CH methylene vibrations as the anhydrous milk fats crystal

298 romatics, some cationic and one neutral dye (methylene violet), also stiffened the Li(+) GB hydrogel.

299 The 20R- and 20S-isomers of 25-hydroxy-2-methylene-vitamin D3 and 3-desoxy-1alpha,25-dihydroxy-2-

300 itamin D3 and 3-desoxy-1alpha,25-dihydroxy-2-methylene-vitamin D3 have been synthesized.