ライフサイエンスコーパス: nucleocytoplasmic

1 eventing histone deacetylation by increasing nucleocytoplasmic acetyl-CoA levels impairs Wnt3a-induce

2 e cytoplasm, we found that ORF57 shifted the nucleocytoplasmic balance by increasing ORF59 RNA accumu

3 rins (Kaps), that mediate the trafficking of nucleocytoplasmic cargoes while also generating a select

4 A critical role for linchpin residues in nucleocytoplasmic coagulation and other forms of free ra

5 of GAPDH was studied as an in vitro model of nucleocytoplasmic coagulation.

6 lfide-cross-linked state via the process of "nucleocytoplasmic coagulation." Here, free radical-induc

7 cooperation between the chloroplast and the nucleocytoplasmic compartment during plant growth and de

8 We detected an age-dependent loss of nucleocytoplasmic compartmentalization (NCC) in donor fi

9 f their transcript isoforms, indicating that nucleocytoplasmic compartmentalization is a cell-specifi

10 Thus, nucleocytoplasmic compartmentalization of licensing fact

11 Nucleocytoplasmic coupling is mediated by outer nuclear

12 criptome analyses have typically disregarded nucleocytoplasmic differences.

13 ses prevail concerning the possible roles of nucleocytoplasmic distribution and trafficking of Gal3 a

14 or 3 (NXF3) as a transporter that alters the nucleocytoplasmic distribution of box C/D snoRNAs from t

15 By genetically manipulating the nucleocytoplasmic distribution of Cdc55, we showed that

16 nd reciprocally regulates protein levels and nucleocytoplasmic distribution of GI in Arabidopsis.

17 e wanted to explore the possibility that the nucleocytoplasmic distribution of IkappaBalpha can be us

18 s spectrometry measurements suggest that the nucleocytoplasmic distribution of RNA binding proteins,

19 There was no change in the nucleocytoplasmic distribution of Snail1 using wild type

20 s of IL-6-induced STAT3-HDAC1 interaction on nucleocytoplasmic distribution of STAT3.

21 As does not have a significant impact on the nucleocytoplasmic distribution of their target isoforms.

22 In line with its obligatory nucleocytoplasmic distribution, DNA binding was only obs

23 e isoforms of one gene can display different nucleocytoplasmic distributions.

24 egalovirus relies on elaborate mechanisms of nucleocytoplasmic egress of viral particles.

25 ear pore complex (NPC), the sole gateway for nucleocytoplasmic exchange in eukaryotic cells, allows f

26 assembly that serves as the sole mediator of nucleocytoplasmic exchange in eukaryotic cells.

27 Our results document regulated nucleocytoplasmic exchange of C3G in response to physiol

28 ponents of all eukaryotic cells that mediate nucleocytoplasmic exchange.

29 clear pore complexes (NPCs) are gateways for nucleocytoplasmic exchange.

30 ransport complexes responsible for selective nucleocytoplasmic exchange.

31 in double nuclear membranes, which carry out nucleocytoplasmic exchange.

32 e complexes are essential for the control of nucleocytoplasmic exchange.

33 nuclear pore complexes (NPCs) controls bulk nucleocytoplasmic exchange.

34 oplasm and a major platform that coordinates nucleocytoplasmic exchanges, gene expression, and genome

35 P K. hnRNP K knockdown compromised NF-M mRNA nucleocytoplasmic export and translation, but had no eff

36 dependent phosphorylation site essential for nucleocytoplasmic export of LKB1(S) and consequent AMPK

37 both in loss of paraspeckles and in enhanced nucleocytoplasmic export of mRNAs containing inverted Al

38 Formation of the Rev-RRE complex signals nucleocytoplasmic export of unspliced and partially spli

39 ress in Schizosaccharomyces pombe, where the nucleocytoplasmic HMG protein Oxs1 acts cooperatively wi

40 In the classical nucleocytoplasmic import pathway, nuclear localization s

41 ntral role in macromolecular trafficking and nucleocytoplasmic information transfer, the nuclear pore

42 only in D5 but also in other viruses of the nucleocytoplasmic large DNA virus (NCLDV) clade.

43 homologous to conserved genes of eukaryotic nucleocytoplasmic large DNA viruses, resulting in the di

44 ith the majority apparently belonging to the nucleocytoplasmic large DNA viruses.

45 arch on perinuclear factories induced by the nucleocytoplasmic large DNA viruses.

46 virus satellites that prey on giant viruses (nucleocytoplasmic large DNA viruses; NCLDVs), which are

47 ses have been discovered and assigned to the nucleocytoplasmic large dsDNA virus (NCLDV) clade.

48 and fractionation reveal that HopQ1 exhibits nucleocytoplasmic localization, while HopQ1 dephosphoryl

49 on 12 yield Esrp1 isoforms with differential nucleocytoplasmic localization.

50 e propose a model of stepwise acquisition of nucleocytoplasmic mechanistic complexity and demonstrate

51 RM1/Exportin-1) receptor pathway, but retain nucleocytoplasmic mobility.

52 Nucleocytoplasmic molecular transport, however, is tight

53 os is a pause in cell cycle regulated by the nucleocytoplasmic (N/C) ratio.

54 The MBT is triggered by a critical nucleocytoplasmic (N/C) ratio; however, the molecular ba

55 Conversely, reduced expression of both nucleocytoplasmic (ncOGT) and mitochondrial (mOGT) OGT i

56 Rather, the mRNA for nucleocytoplasmic O-linked N-acetylglucosaminyltransfera

57 machinery that is predicted to regulate the nucleocytoplasmic O-Man glycosylations.

58 taset allows unprecedented insights into the nucleocytoplasmic organisation of eukaryotic cells, into

59 oocytes via microdissection and measured the nucleocytoplasmic partitioning of approximately 9,000 pr

60 Nucleocytoplasmic partitioning of core clock components

61 vel a potential role of SPA proteins in COP1 nucleocytoplasmic partitioning, we monitored the subcell

62 Here we show that nucleocytoplasmic posttranslational modification of prot

63 Nucleolin (NCL) is a nucleocytoplasmic protein involved in many biological pr

64 Ac transferase (OGT), O-GlcNAcase (OGA), and nucleocytoplasmic protein O-GlcNAcylation in the most ba

65 lar system to study gene transactivation and nucleocytoplasmic protein trafficking.

66 on of 4E-T(ransporter), an additional P-body nucleocytoplasmic protein, revealed that 4E-T colocalize

67 ked beta-N-acetylglucosamine modification of nucleocytoplasmic proteins (O-GlcNAc) confers stress tol

68 O-linked to serine and threonine residues of nucleocytoplasmic proteins (O-GlcNAc) has been linked to

69 However, the type of yeast O-Man nucleocytoplasmic proteins and the localization of ident

70 fication of serine and threonine residues of nucleocytoplasmic proteins by beta-N-acetylglucosamine (

71 glycosylation is thought to be restricted to nucleocytoplasmic proteins of eukaryotes and is mediated

72 inked beta-N-acetylglucosamine (O-GlcNAc) on nucleocytoplasmic proteins serves as a nutrient sensor t

73 egulatory post-translational modification of nucleocytoplasmic proteins that has been implicated in m

74 post-translational signaling modification of nucleocytoplasmic proteins that is essential for embryon

75 a common post-translational modification of nucleocytoplasmic proteins with beta-N-acetyl-glucosamin

76 s a common posttranslational modification of nucleocytoplasmic proteins with beta-N-acetylglucosamine

77 onsive post-translational O-GlcNAcylation of nucleocytoplasmic proteins.

78 on and off serine and threonine residues of nucleocytoplasmic proteins.

79 residues to serine and threonine residues of nucleocytoplasmic proteins.

80 rring on the serine or threonine residues of nucleocytoplasmic proteins.

81 ible for catalyzing removal of O-GlcNAc from nucleocytoplasmic proteins.

82 However, not all P-body components are nucleocytoplasmic proteins; rck/p54, Dcp1a, Edc3, Ge-1,

83 r scale and simultaneously maintain a normal nucleocytoplasmic ratio across a syncytium up to the cen

84 Twine protein destruction was timed by the nucleocytoplasmic ratio and depended on the activation o

85 ow that this destruction is triggered by the nucleocytoplasmic ratio-dependent onset of zygotic trans

86 alian cells by picornaviruses results in the nucleocytoplasmic redistribution of certain host cell pr

87 rus 2A proteinase is sufficient to cause the nucleocytoplasmic redistribution of SRp20.

88 athway antagonists that are epistatic to the nucleocytoplasmic regulator Suppressor of Fused [Su(fu)]

89 The Mollivirus nucleocytoplasmic replication cycle was analyzed using a

90 HuR is a ubiquitous nucleocytoplasmic RNA-binding protein that exerts pleiot

91 thelial tubules are forming and branching, a nucleocytoplasmic shift in Yap localization marks the bo

92 ocation involves the binding of scuPA to the nucleocytoplasmic shuttle protein nucleolin through a re

93 ults also imply that p012 could constitute a nucleocytoplasmic shuttle protein, a feature that could

94 titative assay, which detects differences in nucleocytoplasmic shuttling among seven canonical SR pro

95 s, which suggests that aging causes impaired nucleocytoplasmic shuttling and activation of SIRT1 duri

96 The nucleocytoplasmic shuttling and AU-rich RNA-binding prot

97 Whereas human SRY requires nucleocytoplasmic shuttling and coupled phosphorylation,

98 Due to its rapid nucleocytoplasmic shuttling and high expression level in

99 SUMO activation enzyme (SAE) underwent rapid nucleocytoplasmic shuttling and its nuclear accumulation

100 d the D226 mutation impair HuR's PARylation, nucleocytoplasmic shuttling and mRNA binding.

101 MP/PKA-dependent pathway that controls HDAC5 nucleocytoplasmic shuttling and represses gene transcrip

102 e have shown that C9orf72 may be involved in nucleocytoplasmic shuttling and this may have relevance

103 Together, these results revealed WCC nucleocytoplasmic shuttling as an important step in the

104 method provides a powerful tool for studying nucleocytoplasmic shuttling at the nanometer scale under

105 aling, which involves the regulation of Hxk2 nucleocytoplasmic shuttling by phosphorylation-dephospho

106 the variants exhibited selective defects in nucleocytoplasmic shuttling due to impaired nuclear impo

107 sensors that convert kinase activity into a nucleocytoplasmic shuttling equilibrium for visualizing

108 r technology converts phosphorylation into a nucleocytoplasmic shuttling event that can be measured b

109 Second, Urm1 is conjugated to the nucleocytoplasmic shuttling factor cellular apoptosis su

110 Here, we find that Mpk1 regulates Swi6 nucleocytoplasmic shuttling in a biphasic manner.

111 CaMKI enzyme, which exhibits T(c)-dependent nucleocytoplasmic shuttling in AFD.

112 a GATA transcription factor, exhibits rapid nucleocytoplasmic shuttling in response to cAMP waves.

113 e modulation in the nucleus related to their nucleocytoplasmic shuttling in response to induction of

114 hese data also suggest an important role for nucleocytoplasmic shuttling in this conserved family of

115 These results indicate that nucleocytoplasmic shuttling is essential for virus growt

116 Nucleocytoplasmic shuttling is prevalent among many cell

117 Nucleocytoplasmic shuttling of Aft1 is dependent upon mi

118 hREBP activity is regulated in large part by nucleocytoplasmic shuttling of ChREBP protein via intera

119 Dynamic nucleocytoplasmic shuttling of class IIa histone deacety

120 Nucleocytoplasmic shuttling of class IIa of histone deac

121 Moreover, we also demonstrate that nucleocytoplasmic shuttling of Cth2 requires active tran

122 throughout life, acting via Akt to regulate nucleocytoplasmic shuttling of Foxo3, which functions as

123 inine methyltransferase 1 (PRMT1), regulates nucleocytoplasmic shuttling of FUS.

124 Furthermore, we observe cyclical nucleocytoplasmic shuttling of HDAC5 in mouse fibroblast

125 d beta-AR mediated signaling at the level of nucleocytoplasmic shuttling of HDAC5.

126 hat Sik3 reduction interferes with circadian nucleocytoplasmic shuttling of Histone deacetylase 4 (HD

127 Nucleocytoplasmic shuttling of Hxk2 induced by glucose l

128 c7-Reg1 as novel regulatory partners for the nucleocytoplasmic shuttling of Hxk2.

129 STRADalpha induces nucleocytoplasmic shuttling of LKB1.

130 Thus regulated nucleocytoplasmic shuttling of RLIM/Rnf12 coordinates ce

131 olled through reversible phosphorylation and nucleocytoplasmic shuttling of Smad1, Smad5, and Smad8 (

132 Our results demonstrate that nucleocytoplasmic shuttling of SRY is necessary for robu

133 an sex reversal due to subtle defects in the nucleocytoplasmic shuttling of SRY suggests that its tra

134 ins, which are involved in the regulation of nucleocytoplasmic shuttling of target proteins, restrict

135 We employed the nucleocytoplasmic shuttling of the transcriptional repre

136 uence YXXXXLPhi, shared with eIF4G, and is a nucleocytoplasmic shuttling protein found enriched in P-

137 The nucleocytoplasmic shuttling protein Nmd3 is an adaptor f

138 In human cells, DcpS is a nucleocytoplasmic shuttling protein that activates miRNA

139 ous nuclear ribonucleoprotein (hnRNP) K is a nucleocytoplasmic shuttling protein that is a key player

140 Nef-associated factor 1 (Naf1) is a host nucleocytoplasmic shuttling protein that regulates multi

141 at, like its mammalian homologues, Cth2 is a nucleocytoplasmic shuttling protein whose nuclear export

142 We previously demonstrated that ATF2 is a nucleocytoplasmic shuttling protein, and it contains two

143 Nucleophosmin (NPM1) is a nucleocytoplasmic shuttling protein, mainly localized at

144 Nucleophosmin (NPM1) is a nucleocytoplasmic shuttling protein, mainly localized at

145 Since FMRP was previously shown to be a nucleocytoplasmic shuttling protein, we examined the hyp

146 Others have shown that Sox10 is a nucleocytoplasmic shuttling protein.

147 beta(2)-AR mRNA is recognized by the nucleocytoplasmic shuttling RNA-binding protein HuR, whi

148 ranules and permits its nuclear import via a nucleocytoplasmic shuttling sequence in the C-terminal d

149 ated with switching from carrier-independent nucleocytoplasmic shuttling to carrier-mediated nuclear

150 rylation, pancreatic and duodenal homeobox 1 nucleocytoplasmic shuttling, and transcription of insuli

151 this family of proteins are known to undergo nucleocytoplasmic shuttling, but little is known about t

152 his dynamics is determined by the balance of nucleocytoplasmic shuttling, formin- and redox-dependent

153 that is involved in pre-mRNA processing and nucleocytoplasmic shuttling, has Sumo1 E3 ligase activit

154 e process involving Smad phosphorylation and nucleocytoplasmic shuttling, regulated by rigidity-depen

155 apable of executing NPM's described roles in nucleocytoplasmic shuttling, ribosome export and cell cy

156 SmgGDS undergoes nucleocytoplasmic shuttling, suggesting that it has both

157 259 and 498, whose phosphorylations control nucleocytoplasmic shuttling.

158 reen to identify pathways controlling TDP-43 nucleocytoplasmic shuttling.

159 2+) channel, as a strong modulator of TDP-43 nucleocytoplasmic shuttling.

160 ependent kinase, a negative regulator of HuR nucleocytoplasmic shuttling.

161 he geometry of the syncytium and kinetics of nucleocytoplasmic shuttling.

162 Recently it was shown that UL84 displays nucleocytoplasmic shuttling.

163 olled through reversible phosphorylation and nucleocytoplasmic shuttling.

164 ranslocation of CaMKIV, which preceded HMGB1 nucleocytoplasmic shuttling.

165 alpha complex but it does not facilitate its nucleocytoplasmic shuttling.

166 Within oocytes, Foxo3 is regulated by nucleocytoplasmic shuttling.

167 ains defects in NFATc4 rephosphorylation and nucleocytoplasmic shuttling.

168 og1, revealed both coordinated and decoupled nucleocytoplasmic shuttling.

169 interacts with nucleoporins to promote Smad2 nucleocytoplasmic shuttling.

170 lizing functionally related mRNAs within the nucleocytoplasmic space of mitotic cells and suggest tha

171 ver, the trypanosome NPC has almost complete nucleocytoplasmic symmetry, in contrast to the opisthoko

172 cates to the nucleus by the karyopherin-beta nucleocytoplasmic system and binds DNA.

173 we present evidence that indicates that Hxk2 nucleocytoplasmic traffic is regulated by phosphorylatio

174 All nucleocytoplasmic traffic of macromolecules occurs throu

175 The massive nuclear pore complex mediates nucleocytoplasmic traffic ranging from a single histone

176 e developed an efficient means of inhibiting nucleocytoplasmic traffic.

177 myocarditis virus (EMCV) shuts off host cell nucleocytoplasmic trafficking (NCT) by inducing hyperpho

178 wn of certain nucleoporins and components of nucleocytoplasmic trafficking alter integration site pre

179 partners to bring about inhibition of active nucleocytoplasmic trafficking and cap-dependent translat

180 otent antihost inhibition of active cellular nucleocytoplasmic trafficking by triggering aberrant hyp

181 In addition, our results indicate that nucleocytoplasmic trafficking can tolerate both partial

182 We determined that the rates of nucleocytoplasmic trafficking for both Gal80 and Gal3 ar

183 host import/export factors that mediate Gag nucleocytoplasmic trafficking for virion assembly.

184 tracellular protein redistribution, impaired nucleocytoplasmic trafficking has emerged as a mechanism

185 numerous fusion oncoproteins whose effect on nucleocytoplasmic trafficking is poorly understood.

186 fusion proteins displayed tonicity-dependent nucleocytoplasmic trafficking like TonEBP.

187 nducible kinase 2 (SIK2) and SIK3 to promote nucleocytoplasmic trafficking of class IIa HDACs.

188 nucleoporin that plays complex roles in the nucleocytoplasmic trafficking of macromolecules.

189 e the nuclear envelope (NE) and regulate the nucleocytoplasmic trafficking of macromolecules.

190 ithin the nuclear envelope, NPCs mediate the nucleocytoplasmic trafficking of numerous cellular compo

191 rowth and differentiation by controlling the nucleocytoplasmic trafficking of proteins and RNAs, some

192 dent activation of the NLS is crucial in the nucleocytoplasmic trafficking of TonEBP.

193 the nuclear pore complexes, (iii) inhibiting nucleocytoplasmic trafficking, and (iv) inhibiting trans

194 motif required by L to mediate inhibition of nucleocytoplasmic trafficking, significantly reduced L-p

195 rotein homeostasis, with specific defects in nucleocytoplasmic trafficking, the induction of stress a

196 rmed nucleoporins (Nups), mediates selective nucleocytoplasmic trafficking.

197 FAK complexes, depending on their respective nucleocytoplasmic trafficking.

198 tant to building a complete understanding of nucleocytoplasmic trafficking.

199 suggesting the existence of myosin XI-driven nucleocytoplasmic trafficking.

200 2) phosphorylation correlated with transient nucleocytoplasmic translocation of CREB.

201 ef-1 activated MAPK signaling, which induced nucleocytoplasmic translocation of FOXO1 and PDX1 and le

202 pendent phosphorylation of Ser-399 triggered nucleocytoplasmic translocation of LKB1(S) in response t

203 Here we show that this is triggered by nucleocytoplasmic translocation of the transcription fac

204 rtial sequestration of factors essential for nucleocytoplasmic transport (Gle1 and RanGAP1), and intr

205 was originally identified as a regulator of nucleocytoplasmic transport [1] and subsequently found t

206 studies offered clues that mHTT may disrupt nucleocytoplasmic transport and a mutation of an NUP can

207 entify polyglutamine-dependent inhibition of nucleocytoplasmic transport and alteration of nuclear in

208 In addition, LKB1 nucleocytoplasmic transport and AMPK activation in respo

209 nuclear pore complex (NPC) has dual roles in nucleocytoplasmic transport and chromatin organization.

210 uclear pore complex (NPC) is responsible for nucleocytoplasmic transport and constitutes a hub for co

211 oughout the cell cycle, including interphase nucleocytoplasmic transport and mitotic spindle assembly

212 c nuclear permeability barrier and selective nucleocytoplasmic transport are maintained by nuclear po

213 ycine (FG) repeats play an important role in nucleocytoplasmic transport as they bind to transport re

214 Here we demonstrate that nucleocytoplasmic transport at the membrane domain surro

215 The RanGTPase acts as a master regulator of nucleocytoplasmic transport by controlling assembly and

216 tain this conformation throughout the entire nucleocytoplasmic transport cycle.

217 ever little is known about the regulation of nucleocytoplasmic transport during the formation of myof

218 and serves as the sole conduit to facilitate nucleocytoplasmic transport in eukaryotes.

219 s) are key cellular transporter that control nucleocytoplasmic transport in eukaryotic cells, but its

220 cts in the nuclear pore complex and impaired nucleocytoplasmic transport in Huntington's disease (HD)

221 Therefore, we evaluated the NPC and nucleocytoplasmic transport in multiple models of HD, in

222 s provide evidence for an important role for nucleocytoplasmic transport in the pathogenic mechanism

223 Dysfunction in nucleocytoplasmic transport is also an emerging theme in

224 permeability, selectivity, and the speed of nucleocytoplasmic transport is an assembly of natively u

225 Nucleocytoplasmic transport is facilitated by nuclear po

226 Nucleocytoplasmic transport is mediated by nuclear pore

227 Nucleocytoplasmic transport is mediated by nuclear pore

228 Nucleocytoplasmic transport is mediated by the interacti

229 Nucleocytoplasmic transport is sustained by karyopherins

230 asm, it may mediate a connection between the nucleocytoplasmic transport machinery and the endosomal

231 exportins represent an essential part of the nucleocytoplasmic transport machinery.

232 rovides several binding sites for the mobile nucleocytoplasmic transport machinery.

233 rovides a multitude of binding sites for the nucleocytoplasmic transport machinery.

234 concomitantly can interact with the soluble nucleocytoplasmic transport machinery.

235 common mechanism for SUMOylation to regulate nucleocytoplasmic transport may lie in the interplay bet

236 the NPC, taking a central role in the vital nucleocytoplasmic transport mechanism.

237 Nucleocytoplasmic transport occurs exclusively through n

238 ant function of small GTPases in the cell is nucleocytoplasmic transport of both proteins and RNA.

239 Retroviral replication requires the nucleocytoplasmic transport of both spliced and unsplice

240 1 phosphorylation at S307, which directs the nucleocytoplasmic transport of LKB1 and consequent AMPK

241 role that can be considered dependent on the nucleocytoplasmic transport of macromolecules (i.e. is t

242 The nuclear pore complex mediates nucleocytoplasmic transport of macromolecules in eukaryo

243 In eukaryotes, the nucleocytoplasmic transport of macromolecules is mainly

244 The NPC regulates nucleocytoplasmic transport of macromolecules, utilizing

245 enetic information is regulated by selective nucleocytoplasmic transport of messenger RNA:protein com

246 Regulated nucleocytoplasmic transport of proteins is central to ce

247 inson-Gilford progeria syndrome inhibits the nucleocytoplasmic transport of several factors with key

248 t factors underlie the efficiency of certain nucleocytoplasmic transport pathways.

249 Here we analyzed the nucleocytoplasmic transport properties of both Gag prote

250 show that importin beta, a well established nucleocytoplasmic transport protein, interacts with comp

251 irst time revealed a novel role that MOG1, a nucleocytoplasmic transport protein, plays in cardiac ph

252 estration and impairment of nuclear HR23 and nucleocytoplasmic transport proteins is an outcome of, a

253 s will continue to be applied to outstanding nucleocytoplasmic transport questions, and that the appr

254 Continuous cycles of nucleocytoplasmic transport require disassembly of trans

255 answer by other means, yet the complexity of nucleocytoplasmic transport requires that interpretation

256 The nuclear pore complex gates nucleocytoplasmic transport through a massive, eight-fol

257 Cardioviruses disrupt nucleocytoplasmic transport through the activity of thei

258 The nuclear pore complex (NPC) mediates nucleocytoplasmic transport through the nuclear envelope

259 f G4C2 repeat expansion is the compromise of nucleocytoplasmic transport through the nuclear pore, re

260 There is significant evidence linking nucleocytoplasmic transport to cell cycle control.

261 ights into how these nucleoporins coordinate nucleocytoplasmic transport to mount a robust immune res

262 Nuclear transport receptors (NTRs) mediate nucleocytoplasmic transport via their affinity for unstr

263 Although global nucleocytoplasmic transport was not significantly altere

264 easomal degradation and proteins involved in nucleocytoplasmic transport were sequestered by poly(GA)

265 This mechanism may coordinate nucleocytoplasmic transport with other mitogenic effects

266 model of an intact NPC structure to examine nucleocytoplasmic transport with refined spatial and tem

267 romised nuclear envelope integrity, impaired nucleocytoplasmic transport, and accumulation of DNA dou

268 ical for cellular processes such as mitosis, nucleocytoplasmic transport, and nuclear envelope format

269 ct role of the disorder within FG repeats in nucleocytoplasmic transport, and resolves the apparent c

270 he nuclear pore complexes (NPCs) that enable nucleocytoplasmic transport, and the spindle pole bodies

271 -FTD spectrum disorder, including autophagy, nucleocytoplasmic transport, DNA damage repair, pre-mRNA

272 gradient of RanGTP on chromatin that directs nucleocytoplasmic transport, mitotic spindle assembly an

273 ll GTPase Ran is best known for its roles in nucleocytoplasmic transport, mitotic spindle assembly, a

274 y of GTPases, is best known for its roles in nucleocytoplasmic transport, mitotic spindle fiber assem

275 The NUP107 complex is important for nucleocytoplasmic transport, nuclear envelope assembly,

276 with recent reports showing that DPRs affect nucleocytoplasmic transport, our results point to an imp

277 g karyopherins and effectors of Ran-mediated nucleocytoplasmic transport, providing insight into pote

278 included 1) mRNAs within the nucleolus when nucleocytoplasmic transport, rRNA biogenesis, or RNA pro

279 es in multiple cellular processes, including nucleocytoplasmic transport, spindle formation, and post

280 P) is important to Ran signaling involved in nucleocytoplasmic transport, spindle organization, and p

281 Nucleocytoplasmic transport, the trafficking of macromol

282 echanics is essential for characterizing the nucleocytoplasmic transport, which has a central importa

283 pore complex encloses a central channel for nucleocytoplasmic transport, which is thought to consist

284 The nuclear pore complex (NPC) mediates all nucleocytoplasmic transport, yet its structure and bioge

285 oncentration in the nucleus is important for nucleocytoplasmic transport.

286 Nups in the nuclear pore, and mechanisms of nucleocytoplasmic transport.

287 ptors (Karyopherins (Kaps)) that orchestrate nucleocytoplasmic transport.

288 mbers (karyopherins) mediate the majority of nucleocytoplasmic transport.

289 t, consistent with its essential function in nucleocytoplasmic transport.

290 ility of Cic by controlling the rates of its nucleocytoplasmic transport.

291 zation and aggregation of NUPs and defective nucleocytoplasmic transport.

292 TPase Ran and the importin proteins regulate nucleocytoplasmic transport.

293 G domain nucleoporins, which are crucial for nucleocytoplasmic transport.

294 TG (RAN) translation proteins also disrupted nucleocytoplasmic transport.

295 nonsense-mediated mRNA decay pathway, and to nucleocytoplasmic transport.

296 sphorylation site which is essential for its nucleocytoplasmic transport.

297 hting the importance of the shape effects in nucleocytoplasmic transport.

298 ) are 110-megadalton assemblies that mediate nucleocytoplasmic transport.

299 lex (NPC) filaments and is a docking site in nucleocytoplasmic transport.

300 nstitutes the sole gateway for bidirectional nucleocytoplasmic transport.