ライフサイエンスコーパス: phagocytic cell

1 d efficient antigen presentation in the host phagocytic cell.

2 s replace CCR2(+) macrophages as the primary phagocytic cell.

3 by liver-, spleen-, and bone marrow-resident phagocytic cells.

4 ectin-3), a gene typically expressed only in phagocytic cells.

5 ), modulate essential interactions with host phagocytic cells.

6 ) is a catalytic subunit of NOX expressed in phagocytic cells.

7 neration of reactive oxygen species (ROS) in phagocytic cells.

8 with the presence of alternatively activated phagocytic cells.

9 increased transferrin receptor expression by phagocytic cells.

10 ptake, and killing of many microorganisms by phagocytic cells.

11 (iNOS) in the innate response of mononuclear phagocytic cells.

12 tion of extensive retraction was specific to phagocytic cells.

13 leading to C3b opsonization and ingestion by phagocytic cells.

14 ction of Yersinia outer proteins (Yops) into phagocytic cells.

15 tion of the major exosporium protein BclA by phagocytic cells.

16 lem of intracellular survival, especially in phagocytic cells.

17 mulatory beta-glucans from detection by host phagocytic cells.

18 hanism that controls IFN-gamma production by phagocytic cells.

19 ype K1 CPS elicits chemokine production from phagocytic cells.

20 targets for complement receptors present on phagocytic cells.

21 tion between Gram-negative bacteria and host phagocytic cells.

22 xidative antimicrobial molecules produced by phagocytic cells.

23 HSV-induced infiltration of tumor-associated phagocytic cells.

24 les from superoxide that is released by host phagocytic cells.

25 esponse to spirochetal lysate stimulation of phagocytic cells.

26 via modulation of NADPH oxidase activity in phagocytic cells.

27 ocytic leukocytes, as well as in certain non-phagocytic cells.

28 es and has been found to persist inside host phagocytic cells.

29 fection by cell-to-cell spread from adjacent phagocytic cells.

30 ed by Abeta(42) to chemoattract and activate phagocytic cells.

31 crobial peptides, mucociliary clearance, and phagocytic cells.

32 the rituximab-CD20 complexes were removed by phagocytic cells.

33 respiration and exogenously produced by host phagocytic cells.

34 hogens that survive and multiply within host phagocytic cells.

35 udying the interaction of C. neoformans with phagocytic cells.

36 anism, possibly by improving survival within phagocytic cells.

37 g P. aeruginosa resistant to antibiotics and phagocytic cells.

38 defense mechanisms of macrophages and other phagocytic cells.

39 , suggesting a specificity of C5 cleavage by phagocytic cells.

40 icity mediated by complement-fixing DSAs and phagocytic cells.

41 e dying organism are engulfed by circulating phagocytic cells.

42 uent rapid elimination through the action of phagocytic cells.

43 to determine how rickettsiae survive within phagocytic cells.

44 ent activation, and appearance of defects in phagocytic cells.

45 obably mediates its effects via host-derived phagocytic cells.

46 e mechanisms ensuring their survival in host phagocytic cells.

47 is the bacterium's ability to enter into non-phagocytic cells.

48 es these amyloid-beta-dependent functions in phagocytic cells.

49 f the reactive oxygen generation seen in non-phagocytic cells.

50 epitope directed against the Fc component of phagocytic cells.

51 xygen and nitrogen intermediates produced by phagocytic cells.

52 ells and were endocytosed by nonprofessional phagocytic cells.

53 s and uses plasmid-encoded factors to resist phagocytic cells.

54 layer, particles of which can be ingested by phagocytic cells.

55 nd a specific viability deficit inside human phagocytic cells.

56 the interactions between A. pittii and human phagocytic cells.

57 diabetic mice transfer secretory vesicles to phagocytic cells.

58 ed for activation of engulfment receptors on phagocytic cells.

59 everal cell types, including mitotic and non-phagocytic cells.

60 osome-sensitive population of liver-resident phagocytic cells.

61 ins to efficiently and differentially target phagocytic cells.

62 y regulated genes were highly induced inside phagocytic cells.

63 anisms for fungal persistence and killing in phagocytic cells.

64 understanding of F. tularensis infection of phagocytic cells.

65 latum is a respiratory pathogen that infects phagocytic cells.

66 amentous actin and altered actin dynamics in phagocytic cells.

67 n debris that is usually promptly cleared by phagocytic cells.

68 more efficient at killing and escaping these phagocytic cells.

69 y selective retention within macrophages and phagocytic cells.

70 taken up by peritoneal macrophages and other phagocytic cells.

71 uoG mutant spread to a larger number of lung phagocytic cells.

72 lammasome, Th17 signaling and recruitment of phagocytic cells.

73 ession of rhsT was induced upon contact with phagocytic cells.

74 athogen that invades both phagocytic and non-phagocytic cells.

75 is their rapid recognition and engulfment by phagocytic cells (a process called efferocytosis).

76 Increased phagocytic cell activity was maintained after apoptotic

77 antiinflammatory cytokine interleukin 10 by phagocytic cells after the apoptotic phase of the infect

78 eviously showed that impairment of recruited phagocytic cells allowed survival of ExoU-secreting P. a

79 l role in GAS resistance to human and murine phagocytic cells, allowing the bacteria to persist at th

80 However, many phagocytic cells also act as antigen-presenting cells an

81 nsmission of pathogenic mycobacteria between phagocytic cells also depends on nonlytic ejection throu

82 Phagocytic cells also express exPS, which is dependent o

83 of tumor infiltration with MMP-9 expressing phagocytic cells and a higher degree of coverage of endo

84 with IL-6 that can bind Fcgamma receptors on phagocytic cells and are rapidly internalized.

85 complement but not between an OPA using HL60 phagocytic cells and baby rabbit complement.

86 It is believed that survival within phagocytic cells and cell-to-cell spread via actin protr

87 important virulence factors that lyse human phagocytic cells and contribute to immune evasion.

88 by far the most abundant agent generated by phagocytic cells and may be the major mediator of inflam

89 family, NOX-2 (gp91(phox)), is expressed in phagocytic cells and mediates microbicidal activities.

90 Macrophages are myeloid-derived phagocytic cells and one of the first immune cell types

91 cation channel, inhibited ROS production in phagocytic cells and prevented endotoxin-induced lung in

92 nocytes, and T lymphocytes, in activation of phagocytic cells and release of granule-based enzymes an

93 plicate in professional and non-professional phagocytic cells and subvert immune responses for chroni

94 ges and it was defective for invasion of non-phagocytic cells and survival within macrophages; but it

95 te that Mac-1 expression is critical on both phagocytic cells and T cells for the development of demy

96 production elicited by B. burgdorferi Ags in phagocytic cells and the development of murine Lyme arth

97 een B. anthracis spores with nonprofessional phagocytic cells and thus direct the spores towards upta

98 ytic cell line HL-60 served as the source of phagocytic cells, and a commercial preparation of intrav

99 to electrostatically repel pneumococci from phagocytic cells, and avoidance of phagocytosis correlat

100 antly by activated dendritic cells (DCs) and phagocytic cells, and both cytokines induce IFN-gamma se

101 In tissues, fibroblasts are phagocytic cells, and in culture, they have been shown t

102 arkers (CD14, CD16, and CD172a), were potent phagocytic cells, and produced TNF in response to LPS.

103 cells secrete chemotactic factors to attract phagocytic cells, and we found that S1P potently stimula

104 he vascular endothelium, bone marrow-derived phagocytic cells are a major site of IgG homeostasis.

105 What has emerged from these studies is that phagocytic cells are essential for protection and that d

106 L. monocytogenes to invade non-professional phagocytic cells are not fully understood.

107 the clearance of such debris by mononuclear phagocytic cells are poorly understood.

108 ver, the molecular mechanism(s) by which the phagocytic cells are recruited in the PPT1-KO mouse brai

109 By analyzing the relative proportion of phagocytic cells as a function of cell cycle phase, we o

110 The macrophage was the primary phagocytic cell at all times of infection, but neutrophi

111 ant to phagocytosis by both murine and human phagocytic cells at levels comparable to those of flagel

112 pathogenesis of gas gangrene and the lack of phagocytic cells at the site of infection.

113 f a filter that separated them from the host phagocytic cells below.

114 receptor 1 (CR1) expressed on the surface of phagocytic cells binds complement-bound immune complexes

115 not inhibit S. aureus binding and uptake by phagocytic cells but instead attenuates S. aureus induce

116 and production of reactive oxygen species in phagocytic cells, but mechanisms have not been fully def

117 Inflammation is mediated primarily by phagocytic cells, but the mechanisms of CNS tissue destr

118 onella pneumophila is able to survive inside phagocytic cells by an internalization route that bypass

119 gent of bacterial pneumonia, survives inside phagocytic cells by avoiding rapid targeting to the lyso

120 Depletion of phagocytic cells by clodronate liposomes in wild-type mi

121 represent part of the general activation of phagocytic cells by endotoxin.

122 ella enterica serovar Typhimurium invade non-phagocytic cells by injecting bacterial effector protein

123 In contrast, in vivo depletion of phagocytic cells by injection of liposomes containing cl

124 nation to the brain, an effect that required phagocytic cells, C1q, and FcgammaRIII (CD16).

125 Despite the presence of these phagocytic cells, chancroid ulcers can persist for month

126 c HL-60 cells, with exogenous PS resulted in phagocytic cell clearance, and this process was further

127 Polymorphonuclear neutrophils (PMN) are phagocytic cells constitutively programmed for apoptotic

128 Recent studies have revealed that these phagocytic cells control the patterning and wiring of th

129 targeted up-regulation of Nox1 expression in phagocytic cells could provide a novel approach in the m

130 hypothesized that P4-mediated activation of phagocytic cells could rapidly and substantially increas

131 en these fungal cells are most vulnerable to phagocytic cell defenses.

132 killer cell-depleted, or carrageenan-treated phagocytic cell-depleted mice were inoculated with 4T1 a

133 D. melanogaster Schneider 2 phagocytic cells displayed decreased phagocytosis and ca

134 he cell-mediated immune system (by targeting phagocytic cells), disrupt epithelial barriers, and libe

135 erium that targets host alveolar mononuclear phagocytic cells during infection.

136 ur study demonstrated that HOCl generated by phagocytic cells during inflammatory episodes has a pote

137 (RNI), were used to investigate the role of phagocytic cells during mucosal and systemic candidiasis

138 conditions such as those encountered within phagocytic cells during the host immune response, iron i

139 in the brain is followed by infiltration of phagocytic cells (e.g. activated microglia, astroglia an

140 nes, and cellular immune defenses, including phagocytic cells (e.g., macrophages).

141 cterial numbers are low relative to those of phagocytic cells, e.g., early in an infection.

142 ease of innate immune-related molecules from phagocytic cells early in the course of infection.

143 us infections through its ability to promote phagocytic cell effector functions.

144 detect IL-6 and ED-1 (a marker of microglial/phagocytic cells), enzyme-linked immunosorbent assay (EL

145 These data indicate that phagocytic cells, especially lung macrophages, can gener

146 otic tumor nodules surrounded by mononuclear phagocytic cells, followed by fibrosis and calcification

147 ellite glial cell precursors are the primary phagocytic cells for apoptotic corpse removal in develop

148 e a useful function in directing hemozoin to phagocytic cells for safe disposal.

149 In vitro, phagocytic cells from C3(+/+) or C3(-/-) mice exhibited

150 The phagocytic cells from MGL1(-/-) mice did not exhibit any

151 Depletion of phagocytic cells from normally developed spleens by trea

152 However, the present study shows that phagocytic cells from patients with either principal for

153 liferation of cyst-lining cells, we depleted phagocytic cells from Pkd1(fl/fl);Pkhd1-Cre mice by trea

154 bial pathogens and glycans on the surface of phagocytic cells from the host.

155 Although professional phagocytic cells harbor intracellular bacteria including

156 s found that the interaction between GXM and phagocytic cells has biological consequences that may co

157 While phagocytic cells have a requisite role in the response t

158 Reactive oxidative species (ROS) produced by phagocytic cells have been ascribed a role in the locali

159 implicated in apoptotic cell (AC) uptake by phagocytic cells; however, their relative dominance in m

160 rvations have established a crucial role for phagocytic cells in host resistance to Salmonella.

161 e of persistent apoptotic-cell nuclei within phagocytic cells in nuc-1 mutants.

162 y of small GTPases play an essential role in phagocytic cells in organization of the actin cytoskelet

163 hese results highlight an unexpected role of phagocytic cells in processing T. gondii oocysts, in lin

164 ptococcus neoformans is poorly recognized by phagocytic cells in the absence of opsonins.

165 Microglia are phagocytic cells in the CNS and actively participate in

166 roglia are the principle immune effector and phagocytic cells in the CNS.

167 Kupffer cells (KC) are abundant phagocytic cells in the liver.

168 Our results indicate that phagocytic cells in the lung are injected with ExoU and

169 We determined that phagocytic cells in the lung were frequently injected wi

170 Because microglia, which are phagocytic cells in the mammalian brain, are bone marrow

171 e presence of C3-deficient serum compared to phagocytic cells in the presence of serum with sufficien

172 f outer segments, as well as the presence of phagocytic cells in the subretinal space.

173 readily taken up by both phagocytic and non-phagocytic cells in vitro after a short (approximately 3

174 ing in both liquid culture and within murine phagocytic cells in vitro and in vivo.

175 ting biocompatible nanoparticle that targets phagocytic cells in vivo and is coated with approximatel

176 has also been described in a variety of non-phagocytic cells, including cancer cells.

177 ind to different receptors on the surface of phagocytic cells, including the beta(2) integrin, comple

178 he causative agent of Lyme borreliosis, with phagocytic cells induces the activation of NF-kappaB and

179 Unlike resident phagocytic cells, inflammatory monocytes produced IL-12,

180 Professional phagocytic cells ingest microbial intruders by engulfing

181 Phagocytic cells inhibit the growth of intracellular pat

182 transcription factors, such as NF-kappa B in phagocytic cells, initiate the proinflammatory cytokine

183 hils (polymorphonuclear leukocytes; PMN) are phagocytic cells instrumental in the clearance of infect

184 Macrophages, phagocytic cells involved in an early phase of host defe

185 Macrophages are specialized phagocytic cells involved in clearing invading pathogens

186 CvGal1 expressed by phagocytic cells is "hijacked" by the parasite Perkinsus

187 lla enterica serovar Typhimurium within host phagocytic cells is a critical step in establishing syst

188 binding and uptake of B. anthracis spores by phagocytic cells is a dynamic process and involves multi

189 in the CNS, whose activation into migratory, phagocytic cells is associated with increased expression

190 nal IL-6 in retinal I/R injury in microglial/phagocytic cells is controlled predominantly by NF-kappa

191 e vaccine strain invasion of nonprofessional phagocytic cells is inhibited by cytochalasin D and noco

192 agents capable of increasing Abeta uptake by phagocytic cells is of potential therapeutic interest fo

193 e ability of this organism to survive inside phagocytic cells is poorly understood but thought to be

194 ryllus schlosseri, cell corpse engulfment by phagocytic cells is the recurrent mechanism of programme

195 CD47, a "don't eat me" signal for phagocytic cells, is expressed on the surface of all hum

196 so called CD11b/CD18), a beta(2) integrin on phagocytic cells, is one such receptor.

197 at the ability of S. aureus strains to evade phagocytic cell killing and to survive temporarily withi

198 eased bacterial clearance, and iv) increased phagocytic cell killing of bacteria compared with tail t

199 ammatory cells to the peritoneum, or improve phagocytic cell killing of pathogens.

200 PKH26-phagocytic cell labeling dye was administered intranasal

201 eveloping a cell-based immunotherapy using a phagocytic cell line, HL-60.

202 spread in L2 fibroblasts, a nonprofessional phagocytic cell line.

203 Clodronate-mediated depletion of phagocytic cells markedly prolonged the serum half-life

204 ells, which were also marked by a microglial/phagocytic cell marker (ED1) in the inner retina.

205 GS-9620 induced phagocytic cell maturation and improved effector-mediate

206 n the vascular circulation, erythrocytes and phagocytic cells may accumulate membrane lipid hydropero

207 of hosts with disseminated candidiasis, that phagocytic cells may play an active role in increasing t

208 I/R injury, and its expression by microglia/phagocytic cells may protect RGC layer neurons from I/R

209 t of lymphocyte specific protein 1 (LSP1) on phagocytic cell motility, stable transfection of LSP1-nu

210 Mononuclear phagocytic cells (MPCs), including macrophages and dendr

211 Phagocytic cell NADPH oxidase (NOX) generates reactive o

212 As the first-responder phagocytic cells, neutrophils are recruited in large num

213 While entry into macrophages and other phagocytic cells occurs constitutively, intracellular in

214 We discovered that Mtb infects phagocytic cells of diverse phenotypes, that the predomi

215 requirements for survival and replication in phagocytic cells of organisms from different kingdoms.

216 l role in the antimicrobial functions of the phagocytic cells of the immune system.

217 Hydrogen peroxide (H2O2) is used by phagocytic cells of the innate immune response to kill e

218 LRRK2 protein is highly expressed in phagocytic cells of the innate immune system, most notab

219 including alveolar macrophages, are primary phagocytic cells of the innate immune system.

220 n embryonic development OECs are the primary phagocytic cells of the primary olfactory nerve.

221 intracellular pathogen that persists within phagocytic cells of the reticuloendothelial system.

222 olism including the sequestration of iron in phagocytic cells of the reticuloendothelial system.

223 r pathogens that survive and multiply within phagocytic cells of their hosts.

224 s, allowing them to survive and replicate in phagocytic cells of vertebrate hosts.

225 opsonophagocytic killing of staphylococci by phagocytic cells offers opportunities to establish such

226 f LPS- and IAV-beads by different subsets of phagocytic cells or LPS-mediated differential activation

227 nce demonstrates that macrophages, and other phagocytic cells, play a key role in regulating tumor gr

228 icroglia (MG), a heterogeneous population of phagocytic cells, play important roles in central nervou

229 Early in infection, phagocytic cells, predominantly neutrophils, are recruit

230 Macrophages are specialized phagocytic cells, present in all tissues, which engulf a

231 al endotoxin concentrations, and circulating phagocytic cell priming and had significantly less pulmo

232 mia, plasma IL-6 concentrations, circulating phagocytic cell priming and pulmonary leukosequestration

233 gration across a hyperpermeable gut barrier, phagocytic cell priming, and cytokinemia are key events

234 e inflammatory response, including activated phagocytic cells, pro- and anti-inflammatory cytokines,

235 but not epithelial cells or resident CD11b+ phagocytic cells, produced CCL2 in response to C. rodent

236 ygenation together with oxidants produced by phagocytic cells promote chronic oxidative stress within

237 Candidate phagocytic cell receptors responsible for the enhancemen

238 Macrophages and other phagocytic cells recognize and engulf these dead cells.

239 ging, PBSC were mixed with carbonyl iron and phagocytic cells removed with samarium cobalt magnets.

240 Defects in the phagocytic cells' respiratory burst lead to life-threate

241 r data suggest that the distinct mononuclear phagocytic cell response seen in cerebral X-ALD results,

242 eated mice confirmed that the elimination of phagocytic cells significantly reduces survival time and

243 the capacity to concentrate drug delivery to phagocytic cells, significantly reducing off-target toxi

244 y a key role in the bactericidal capacity of phagocytic cells such as macrophages and neutrophils.

245 In phagocytic cells such as macrophages, these pathogens mu

246 totic tissue is recognized for engulfment by phagocytic cells such as macrophages.

247 Phagocytic cells such as neutrophils and macrophages are

248 in contact with receptors on the surface of phagocytic cells such as neutrophils, monocytes/macropha

249 These results challenge the convention that phagocytic cells such as the microfold cells solely faci

250 ogen, Francisella survives and replicates in phagocytic cells, such as macrophages.

251 tion between the infecting microorganism and phagocytic cells, such as macrophages.

252 ctin was expressed by hemocytes, circulating phagocytic cells, suggesting a role for Drosophila galec

253 l association of blood-borne fungi with host phagocytic cells that are capable of killing the fungus.

254 Microglia are the resident mononuclear phagocytic cells that are critical for innate and adapti

255 Neutrophils are phagocytic cells that kill microorganisms but it is uncl

256 Macrophages are phagocytic cells that participate in the clearance of ap

257 LPS in murine microglial cells, the resident phagocytic cells that play a pivotal role in inflammator

258 Dendritic cells (DCs) are professional phagocytic cells that play an essential role in host def

259 Macrophages are a diverse population of phagocytic cells that reside in tissues throughout the b

260 ive production of reactive oxygen species in phagocytic cells that results in life-threatening infect

261 SLO and SLS were cytotoxic to epithelial and phagocytic cells that the bacteria would typically encou

262 ts into the signaling pathways in immune and phagocytic cells that underlie sepsis and SIRS and consi

263 ttern receptor recognition to recruitment of phagocytic cells-that occur during UPEC-mediated UTI.

264 the bacterial surface and translocated into phagocytic cells; these cells subsequently underwent inf

265 C. neoformans has the capacity to escape phagocytic cells through a process known as nonlytic exo

266 CRP interacts with phagocytic cells through FcgammaRI and FcgammaRII and ac

267 nalization and intracellular survival within phagocytic cells thus may play an important role in the

268 e analogue inhibited the chemotaxis of human phagocytic cells to a number of formyl peptide receptor-

269 acterial infection depends on the ability of phagocytic cells to be recruited and properly activated

270 ed CD8 T cells secrete cytokines that induce phagocytic cells to engulf and kill bacterial pathogens.

271 ia, interferes with the ability of recruited phagocytic cells to eradicate bacteria from the lung.

272 ental processes or injury must be cleared by phagocytic cells to maintain and repair tissues.

273 (2)O(2) can activate NAD(P)H oxidases in non-phagocytic cells to produce additional oxidant species,

274 ity immunoglobulin G (IgG) and activation of phagocytic cells to produce nitric oxide.

275 these signaling pathways to the response of phagocytic cells to the spirochete and the molecular mec

276 ponse to the interaction of spirochetes with phagocytic cells to TNF-alpha production.

277 idea that B cells evolved from an ancestral phagocytic cell type and provide an evolutionary framewo

278 tiation of metamorphosis and are the primary phagocytic cell type in the pupal neuropil.

279 mammalian brain glia, and identify the major phagocytic cell type responsible for engulfing degenerat

280 nts extends to epithelial cells, a minimally phagocytic cell type.

281 s-under (SIMU), which is expressed in highly phagocytic cell types during development and required fo

282 demonstrates that exogenous exposure of non-phagocytic cell types of vascular origin (smooth muscle

283 cantly more adherence to all nonprofessional phagocytic cell types.

284 ers in apoptotic cell clearance by different phagocytic cell types.

285 the phagolysosomes of neutrophils and other phagocytic cell types.

286 In contrast, infection of phagocytic cells was not affected, leaving intact the ab

287 Internalization of BCG by phagocytic cells was shown to be significantly enhanced

288 bacterial mutant defective for growth within phagocytic cells was shown to be similarly defective for

289 Using PKH26-PCL to label resident phagocytic cells, we demonstrated that Gr-1 Macs were de

290 cells (DCs) were ablated but failed when all phagocytic cells were depleted.

291 protein that is preferentially expressed by phagocytic cells, where it promotes efferocytosis and in

292 and undermines the health of these critical phagocytic cells, which can potentially interfere with t

293 , is involved in the handling of pristane by phagocytic cells, which is required to trigger disease i

294 o the malaria parasite from clearance by the phagocytic cells, which may be an immune escape mechanis

295 or macrophages in the thymus are regarded as phagocytic cells whose function is to clear apoptotic de

296 Thus, MSCs are novel phagocytic cells with a potential for immunotherapy in t

297 on remains unclear because prestimulation of phagocytic cells with microbial molecules is required fo

298 following bacterial internalization by host phagocytic cells with subsequent killing, using the enca

299 n shown to encode a transmembrane protein on phagocytic cells, with two functional sequence motifs in

300 highly expressed in CD68(+) macrophages and phagocytic cells within tuberculosis lesions and that [(