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2 ructural determinants of domain swapping and raise the possibility that a single ion channel subtype
5 otype and phenotype in choanoflagellates and raises the possibility that a protein with C-type lectin
6 Na(+) to regulate Smoothened in our assays, raising the possibility that a Na(+) gradient provides t
7 nal parent-of-origin effects in female mice, raising the possibility that a similar mechanism may con
8 alling in lifespan regulation in C. elegans, raising the possibility that a similar process may occur
9 roteins (Env) in the CD4-bound conformation, raising the possibility that accumulating CD4 at the sur
10 for the etiology of human uveitis, but also raise the possibility that activation of autoreactive TC
11 (CD80 upregulation) signaling mechanisms and raise the possibility that activation of P2X7R could pla
13 s unravel a new regulatory role for ADAR and raise the possibility that ADAR mediates the differentia
15 stream of the BCR is dampened in GC B cells, raising the possibility that Ag presentation and competi
16 iated at least in part through beta-catenin, raising the possibility that agents that modulate beta-c
18 ctors are sex-specific disease modifiers and raising the possibility that aggressive anti-MIF treatme
19 -lysosomal pathway and retromer function and raise the possibility that alterations in these pathways
20 d in energy metabolism and oxidative stress, raising the possibility that AMA may be found in patient
23 evolution than was previously understood and raising the possibility that an age-related clonal proce
25 ntly, however, molecular dating methods have raised the possibility that angiosperms may have existed
30 ainst TGF-beta-induced pro-fibrotic activity raises the possibility that anti-lipidogenic therapy may
31 ast Hsp90 (Hsp82) conformation and function, raising the possibility that appearance of this PTM in h
40 eristics of early HIV/SIV infection in mind, raising the possibility that better performance could be
41 enescence in individuals with HCV infection, raising the possibility that blocking this negative-sign
46 interaction between the receptor and c-Cbl, raising the possibility that Cbl-b is necessary for c-Cb
50 duced by simple morphological variation, and raise the possibility that changes in swimming pattern m
51 aptic localization and also binds zinc, thus raising the possibility that changing zinc levels modula
52 TOR promotes cholesterol synthesis, our data raise the possibility that cholesterol synthesis and mTO
53 also perturbed in orthologous mouse models, raising the possibility that ciliary dysfunction contrib
54 are relevant to many types of CNS pathology, raising the possibility that CNS precursors could be man
55 which thalamic axons do not grow internally, raised the possibility that Co cells might have an ances
56 esponsive hypothalamo-pituitary-adrenal axis raises the possibility that cocaine-related impairments
57 hat exit the Golgi region toward the surface raised the possibility that compartments distal to the T
58 rotein-protein interactions with each other, raising the possibility that coordination facilitates co
63 e Zika and Dengue viruses' envelope proteins raise the possibility that cross-reactive antibodies ind
66 tributed pathway to mount a complex response raises the possibility that danger sensing is an evoluti
72 imilar pattern was not found for WM lesions, raising the possibility that different factors promote t
75 emerged prior to monkeys' choice initiation, raising the possibility that dopamine impacts impending
78 sis between gut microbiota and host immunity raises the possibility that dysbiosis of the intestinal
80 /HER2 overexpression, E2f3a is up-regulated, raising the possibility that E2F3a is a critical effecto
81 es of multiple middle Pliocene hominins have raised the possibility that early hominins were as speci
82 ipid signals modulate immune cell responses, raising the possibility that early inhibition of iPLA2be
83 iezo1 is amenable to chemical activation and raise the possibility that endogenous Piezo1 agonists mi
86 localization of tight junction proteins and raise the possibility that endothelial S1P1 inhibition m
87 e amount of adducts formed by endogenous FA, raising the possibility that epigenetic mechanisms may c
88 Htt-induced neuronal dysfunction and death, raising the possibility that epigenetic strategies targe
89 h as grid cells, could depend on plasticity, raising the possibility that experience plays a critical
92 n-positive intranuclear neuronal inclusions, raising the possibility that failure of protein quality
93 nt of myelin produced during development and raise the possibility that Fbxw7 could be a target of my
95 erminants of K. pneumoniae pathogenicity and raises the possibility that functional mutations in CD36
99 nsferase Dnmt3b with H3K36me3-rich chromatin raises the possibility that genic DNA methylation is inf
101 grid cell network in the entorhinal cortex, raising the possibility that grid cells contribute to st
102 ify a non-pyroptotic function for GSDMD, and raise the possibility that GSDMD pores represent conduit
103 methylation of lysine 9 on histone 3 (H3K9), raising the possibility that H3K9Me2, a repressive chrom
107 fferentiation and adiponectin secretion, and raise the possibility that human ARL15 haploinsufficienc
108 sNA segments to initiate unwinding they also raise the possibility that hUPF1 has significantly reduc
110 ure to hypoglycemia and increased mortality, raising the possibility that hypoglycemia has adverse ca
111 rain injury and mTOR are linked to epilepsy, raising the possibility that IGF-1 may be epileptogenic.
118 important regulator of CD8+ T cell fate and raise the possibility that increasing proteasome activit
124 c neurons produces acute aversive states and raises the possibility that inhibiting AMPA transmission
125 limiting mitochondrial lipid utilization and raise the possibility that inhibition of fatty acid oxid
126 als that promote resistance to chemotherapy, raising the possibility that inhibitors of KV11.1 could
129 systematically with imposed conditions, this raises the possibility that it may be used as a strain m
130 cific and developmentally controlled manner, raising the possibility that it influences developmental
131 odified other than a single disulphide bond, raising the possibility that it might require additional
132 by data from both animal and human studies, raising the possibility that kidney DDAH1 expression exa
133 vents at polymerizing microtubule plus-ends, raising the possibility that Kif15 motors may synchroniz
136 ing a major impact on wild populations, this raises the possibility that life histories may be influe
137 ls are a major site of virus replication and raised the possibility that, like papillomaviruses, EBV
138 y, with reported values between 6.8 and 9.1, raising the possibility that linear chain synthesis may
140 mph nodes after SVV reactivation in monkeys, raising the possibility that macrophages and dendritic c
141 y glacial-interglacial changes in sea level, raising the possibility that magmatic flux acts as a neg
144 (e.g. type I fibers and cardiomyocytes), and raises the possibility that Mb also serves as an acylcar
148 4 is sufficient to cause memory impairments, raising the possibility that memory problems seen in AD
149 everal smoking-related diseases than whites, raising the possibility that menthol cigarettes contribu
151 tive disorders, such as Parkinson's disease, raising the possibility that microbiota-ENS interactions
152 of heart defects in the cohesinopathies, and raise the possibility that mild mutations in cohesin gen
153 ion in the mitochondrial life cycle and also raise the possibility that mitochondrial turnover events
154 cells from triple A syndrome patients, which raises the possibility that mitotic errors may underlie
156 arning may also involve dopamine modulation, raising the possibility that model-based learning may co
157 Ac in behavioral responses to AMPH, and they raise the possibility that modulation of PV+ interneuron
159 Elevation of DA release in the global KO raised the possibility that motor deficits in a Parkinso
160 ne improved coronary microvascular function, raising the possibility that MR blockade could have bene
161 ational modifications in PB accumulation and raise the possibility that mRNP dynamics are posttransla
163 The unheralded existence of tripartite ICEs raises the possibility that multipartite elements reside
164 atumoral heterogeneity and cancer stem cells raise the possibility that multiple breast cancer subtyp
165 mena produced by crowding of orientation and raises the possibility that multiple classes of object r
166 ss and in vivo muscle mitochondrial function raises the possibility that muscle mitochondrial mechani
168 orally inoculated pigs with a mouse bioassay raises the possibility that naturally exposed pigs could
170 ing studies in substance-use disorders, thus raising the possibility that neural processing of negati
174 ness of commissural axons at the midline and raise the possibility that nuclear signaling may be a co
177 the increased cardiovascular risk in RA, and raises the possibility that optimizing pain management m
181 dback unfavourably on metabolism and growth, raising the possibility that other venting mechanisms be
182 in Duffy-null Africans have been documented, raising the possibility that P. vivax, a virulent pathog
183 are disabled for this activity, our findings raise the possibility that p53 mitigates oncogenic disea
185 acterial variants arise during infection and raise the possibility that pathogen diversification occu
187 However, disparities in fistula placement raise the possibility that patient factors have a role i
188 pluripotent stem cell (iPSC) technology has raised the possibility that patient-specific iPSCs may b
190 d Sca1(+) cells increased MSC proliferation, raising the possibility that PDGF-BB enhances expansion
191 FRbeta, define the underlying mechanism, and raise the possibility that PDGFRbeta-mediated diseases i
192 d (IBA)-mediated auxin homeostasis in roots, raising the possibility that PEN3 exports multiple funct
194 at BRD2 supports boundary activity, and they raise the possibility that pharmacologic BET inhibitors
196 re consistent with previous observations and raise the possibility that pikas might play a previously
197 factor for stroke and myocardial infarction raised the possibility that pioglitazone, which improves
199 observed to increase throughout development, raising the possibility that posttranslational modificat
200 observed a strong neuronal signature, which raises the possibility that PPAR agonists may be targeti
201 es relevant to visually guided behaviors and raise the possibility that propagating activity patterns
202 pha-helix and components of the active site, raising the possibility that RAG2 binding alters the str
203 more complex than previously envisioned and raise the possibility that RE splicing might generate fu
204 sations of the tibia, fibula, and footplate, raising the possibility that re-emergence of hindlimbs d
206 s and neurodegenerative disorders, our study raises the possibility that replication fork progression
207 tase (catalytic subunit) in some cell lines, raising the possibility that RMRP might play a role in t
209 , the noncleaved form is involved in memory, raising the possibility that secreted and full-length AP
212 inant-negative effect on other E3s in vitro, raising the possibility that short circuiting also may s
213 to the size of their closest competitor and raise the possibility that similar plastic responses to
214 re essential for ant social organization and raise the possibility that, similar to mammals, receptor
215 signalling that precedes pathogen encounter, raising the possibility that small molecules targeting S
220 have been identified in some invertebrates, raising the possibility that some of these genes may pla
222 e of cells in the central nervous system has raised the possibility that specific immune-mediated mec
225 A lack of studies on aquatic trackmakers raises the possibility that such traces may be ignored o
227 nous genes that affect virus replication and raise the possibility that synthetic transcription facto
228 the vesicle docking C2B-PIP2 interaction and raise the possibility that Syt1 rings could pre-form on
229 hanced susceptibility to seizures in CJD and raise the possibility that targeting IL-1beta with clini
231 be critical modulators of disease pathology, raising the possibility that targeting aberrant splicing
232 lfactory structures susceptible to aging and raise the possibility that the age-related changes that
238 DNA) in early-stage Alzheimer's disease (AD) raised the possibility that the same neurodegenerative e
240 onstriction, which would potentiate hypoxia, raises the possibility that the bioelectric impact of ne
242 nfirms earlier reports of mixed isolates and raises the possibility that the host range of C. hominis
243 toms; however, the lack of a placebo control raises the possibility that the observed antidepressant
244 ificant percentage of renal cell carcinomas, raising the possibility that the activity of SETD2 is tu
245 y, this activity is reduced in SMA patients, raising the possibility that the aetiology of SMA is lin
246 , which we confirmed using other techniques, raising the possibility that the modification affects th
247 for altered regulation of MLH1 and LRRFIP2, raising the possibility that the modifier affects regula
248 ARL13b that occurs during cilia resorption, raising the possibility that the sensitivity of ARL13b s
249 the presence of JAK/STAT pathway mutations, raising the possibility that the therapeutic potential o
250 the insect chemosensory receptor family and raise the possibility that their ancestral role was in e
255 e pathogenesis of this enigmatic disease and raise the possibility that therapies specifically direct
256 e than has been previously appreciated, thus raising the possibility that there may be unexpected fun
258 old into defined structures and bind ligands raises the possibility that these too might be capable o
259 gions are disproportionately in the tropics, raising the possibility that these ecosystems may be par
260 sion of several RhoGAP genes in BLBC tumors, raising the possibility that these genes may be oncogeni
261 go bulk increases in response to DNA damage, raising the possibility that these linkages are largely
262 c to tumor cells but not normal osteoblasts, raising the possibility that these may be tractable targ
263 ccumulation and associated oxidative stress, raising the possibility that these metabolites play a ro
264 till able to bind Sia on human erythrocytes, raising the possibility that these viruses can use multi
265 play essential roles in parasite infectivity raised the possibility that they could be targeted by pr
266 uish between folded and unfolded EGF repeats raised the possibility that they participate in a qualit
267 ominence as key modulators of host immunity, raising the possibility that they could influence the ou
268 nents from genomes of many lower eukaryotes, raising the possibility that they have been lost or alte
269 s and are reported to promote thermogenesis, raising the possibility that they interact to direct an
270 e efferent neurons inhibit inner hair cells, raising the possibility that they play a role in the pro
271 ional 5' RNA cap structure in eukaryotes and raise the possibility that this 5' NAD(+) cap could modu
272 nown Golgi apparatus-targeted cargos, and we raise the possibility that this nonclassical pathway is
274 tic open/closed conformational change, which raises the possibility that this assumption may not be v
275 for the conservation of Tasmanian devils and raises the possibility that this species is particularly
276 tients compared with hormone naive patients, raising the possibility that this could serve as a bioma
277 ith structural homology to Kdo transferases, raising the possibility that this enzyme is responsible
278 was large and the sample fraction was small, raising the possibility that this estimation bias could
279 reduced early in the life span of Q140 mice, raising the possibility that this may occur in human HD
280 cking, synaptic currents, and spine density, raising the possibility that this mutation may contribut
281 kable number of different ion channel types, raising the possibility that this protein might be invol
282 orm under intracellular reducing conditions, raising the possibility that this unusual dimer might ha
284 nd central memory CD4(+) T-cell populations, raising the possibility that transmitted viral phenotype
286 ion and to be induced by activated Th2 cells raises the possibility that TSLP may be involved in a po
287 opies of adenine- and uridine-rich elements, raising the possibility that undefined trans-acting fact
290 en identified in human cancers, our findings raise the possibility that unresolved RNA:DNA hybrid str
293 balance and can scavenge and store antigens, raising the possibility that vesicular or transcellular
295 teraction that is necessary for viral entry, raising the possibility that viral escape from antibody
299 activated in tumors by somatic alterations, raises the possibility that well tolerated inhibitors ta
300 governing the switch to multicellularity and raises the possibility that YlbF, YmcA and YaaT broadly
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