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6 long-standing question in bioenergetics, and renders a chemical-biological basis for the design of fu
8 ine mutations in the E-cadherin gene (CDH1), renders a lifetime risk of gastric cancer of up to 70%,
9 65 downregulates its binding to the NDSM and renders a selective decrease in sumoylation of substrate
10 osed model for charge-trapping dynamics that renders a time-dependent change in the threshold voltage
12 and redox metabolism) decrease with age and render aging neurons vulnerable to disease-related insul
16 consciousness at the bedside, clinicians may render an inaccurate prognosis, increasing the likelihoo
18 nal approaches employed in the past have not rendered an authoritative microstructural understanding
19 l in interlayer stacking and layer planarity renders an ordered network with a surface area as high a
20 odes and selected tissues and organs were 3D-rendered: anatomical 3D renderings with 50 nm voxel size
22 -can and film preservatives in polymer-resin render and paint, as well as wood preservatives are used
26 able data) conserved in two or more species, rendering any cross-species interactome comparison immed
27 ces between monomeric ApoE3 and ApoE4, which renders ApoE4 thermodynamically less stable, less struct
28 e experiencing of negative emotions, thereby rendering art reception more intense, more interesting,
32 However, the peak widths are incorrectly rendered because ion diffusion, which affects the peak w
33 ments, and disruptions in this structure can render behavior habitual and inflexible.SIGNIFICANCE STA
34 extended angular benzannelation effectively renders Bergman cyclization irreversible due to favorabl
35 the beta3-N452 N-glycan at the I-EGF1 domain rendered beta3 integrin more active than the wild type.
37 pondingly, that ATF4 or NRF2 deficiency also renders cancer cells more resistant to glucose starvatio
39 e context of mitogenic IL-2 signals, thereby rendering CD8 T cells exquisitely dependent upon environ
43 mpaired the accuracy of mRNA translation and rendered cells highly sensitive to oxidative stress.
44 tors abrogates GNA13-induced TIC phenotypes, rendering cells vulnerable to standard-of-care cytotoxic
46 viability in constant light conditions, but renders cells inviable in cycling conditions when light
49 nt information from 3-dimensional gait data, rendering clinical interpretation of impaired movement p
50 resistant temporal lobe epilepsy will not be rendered completely seizure-free after temporal lobe sur
52 uired for LRT persistence even when BvgAS is rendered constitutively active, suggesting the presence
53 2); however, myocardial [(18)F]FDG spillover rendered coronary [(18)F]FDG scans uninterpretable in 27
55 entify novel lipid molecular species may now render current state-of-the-art lipid libraries obsolete
57 esses DC migration and augments DC survival, rendering DCs in LCH lesions trapped and resistant to ce
59 Wild-type and cathepsin K knockout mice were rendered diabetic by streptozotocin (STZ) injections.
64 rotein-coupled receptor kinase 2 (GRK2) that renders DOR analgesically incompetent at the plasma memb
65 logy resolves a number of problems that have rendered ECA ineffective for biosensing applications.
66 glycolytic activity or glucose availability rendered effector T cells significantly less sensitive t
68 that many processes that rely on SmI2 can be rendered enantioselective by the design of suitable liga
70 ially increased substrate scope in that they render even 1,3-enynes, arylalkynes, and electron-rich a
72 s and DS D1 receptors during fear extinction render fear extinction memory resistant to the disruptin
73 Urea-Based Amino-Sugar Mixture, that rapidly renders fixed tissue samples highly transparent and reli
74 d deficiency usually results from failure to render food B12 bioavailable or from dietary inadequacy.
77 tion of this adaptive axis at multiple nodes rendered glioma cells with primary resistance sensitive
78 is glucose dependence prevents hypoglycemia, rendering GLP-1 analogs a useful and safe treatment moda
84 gand 1 (PD-L1) expression on tumor cells can render human CAR T cells (anti-CD19 4-1BBzeta) hypo-func
86 one with a dedicated four-dimensional volume-rendered imaging protocol at varying intervals after TAV
88 acid-stable hemagglutinin (HA) proteins are rendered incapable of pH-induced triggering for membrane
89 4 exhibits white-light emission with a color rendering index (CRI) of 73 which is similar to a fluore
90 ibility theory, suggesting that the A allele renders individuals more sensitive to both positive and
93 rcumvent known resistance mechanisms, can be rendered ineffective by unrecognised adaptations in the
94 iruses inhibited by pseudoknot aptamers were rendered insensitive by a naturally occurring R277K vari
96 type and Ppp1r15a deleted cells and in cells rendered ISR-deficient by CRISPR editing of the Eif2s1 l
98 ion at the promoter of a gene is presumed to render it silent, yet a sizable fraction of genes with m
99 ety of interactions provided by this sorbent rendered it highly efficient for the extraction of aroma
102 C3 current density 10 mA/cm(2) (at -0.75 V), rendering it attractive for solar-to-fuel applications.
103 gmentation and chemical modification of RNA, rendering it less suitable for analysis by techniques th
104 g significantly lowers the (3)Hsigma barrier rendering it the sole reactive state for the reaction.
105 fur-rich character of persulfurated coronene renders it a promising cathode material for lithium-sulf
106 e, insect pathogen and plant symbiont), that renders it an unusually effective model for studying gen
107 Fast and automated calculation of FragFit renders it applicable for implementation of interactive
108 ng intracellular acidification of Salmonella renders it avirulent, suggesting that acid stress pathwa
109 2 amino acids of the endogenous TTP protein renders it constitutively active as an mRNA-destabilizin
112 liance of SIM on algorithmic post-processing renders it particularly sensitive to artifacts that may
114 carries an autosomal recessive mutation that renders its plumage pure white, provides a unique opport
115 ithin the inner plexiform layer (IPL), which renders J-RGCs responsive to light decrements; and (5) d
116 Furthermore, knockdown of GIMAP6 not only rendered Jurkat cells sensitive to apoptosis but also ac
118 lly induced memory reactivation during sleep renders long-term memories of negative experiences more
119 s, such as cationic adjuvant formulation 09, render low-dose vaccination a feasible and promising app
120 show that a critical reliance on glycolysis renders lung SqCC vulnerable to glycolytic inhibition, w
123 chemogenetic stimulation of oxytocin neurons render males sensitive to the distress of an unfamiliar
124 ale clinical trials have not been completed, rendering management decisions to be based on extrapolat
127 ic deficits in the molecular clock regularly render mice with altered mood-associated phenotypes.
128 ced transcriptional remodeling in brown fat, rendering mice sensitive to cold temperature, and dimini
129 Furthermore, intestinal targeting of Baf180 renders mice susceptible to a more aggressive infectious
131 gestive and detoxification mechanisms likely render microbes unnecessary for caterpillar herbivory.
133 of Menninghaus et al. could be deepened and rendered more systematic by recognizing that our emotion
135 neered symbiotic bacteria have been shown to render mosquitoes resistant to the parasite, the challen
136 nsition metal complexes, have been proposed, rendering necessary procedures for their rational benchm
137 gen and used for NADPH/glutathione reduction renders nematodes and human hepatocytes more resistant a
139 NRF1's Neh2L domain with NRF2's Neh2 domain renders NRF1 sensitive to KEAP1-mediated degradation, in
143 relevant adjustments; however, APOE epsilon4 rendered only the medial (beta = -0.22, P = .03) and lat
144 of binding affinity, and thus cooperativity, renders our new cuboctahedral receptor attractive for in
145 tor (olaparib) while overexpression of USP13 renders ovarian cancer cells resistant to chemotherapy.
147 activation in this system, a mechanism that renders PDA cells more invasive and less anchorage-depen
150 il material adjacent to the ablated area was rendered porous in appearance presumably due to local th
151 We introduce an experimental design that renders possible the stringent study of judgment propaga
152 ctability are unique theoretical constructs, rendering predictions and implications from the model su
153 how that CRISPR/Cas9-mediated PTEN depletion rendered PTEN wild-type Hec-1A endometrioid endometrial
154 Thus the selection of proper ripening stage renders reduced formation of acrylamide in plantain chip
156 carry a KDPI over 35 and have therefore been rendered relatively inaccessible to pediatric recipients
157 th activating mutations in the MAPK cascade, rendered resistant to targeted therapies, display dimini
163 nge of nanoparticle and polymeric materials, renders SCPINS (soft-confinement pattern-induced nanopar
164 d on single-walled carbon nanotubes (SWCNTs) rendered selective to dopamine to study its release from
165 We have identified that in human fibroblasts rendered senescent by stress, replicative exhaustion, or
166 curring, pseudoknot-insensitive viruses were rendered sensitive by the inverse K277R mutation, establ
169 This increasing computational complexity renders simulations for individuals with higher cognitiv
170 creased Ki-67 expression in SNU308 cells and rendered SNU308 cells less responsive to 1alpha,25(OH)2D
172 of sound stimuli, somatic EPSP normalization renders spike initiation more sensitive to synapse timin
173 amide coupling, with unreacted surface area rendered stable and low fouling by incorporation of PEG
174 The futile redox cycle rapidly consumes O2, rendering standard assays of Krebs cycle turnover unusab
175 and Trail Making Test Parts A and B and was rendered statistically nonsignificant by APOE epsilon4 i
176 The mesoporous structure of the CNF paper rendered strong adhesion of the AZO layer and exhibited
177 function and the calibration of gas masses) render such comparisons inconclusive in terms of the mas
179 onsiveness to input from oxygen sensors, and renders sustained escape from 21% oxygen transient and c
181 L-17A, and gamma interferon [IFN-gamma]) and rendered T cells refractory to mitogen for a least 18 h
182 l proliferation, blocked IL-2 secretion, and rendered T cells unresponsive to further downstream diff
185 ivity and alters its association with Tap42, rendering Tap42-associated phosphatases unresponsive to
186 ence of mycolic acids (MAs), which, in part, render the bilayer extremely hydrophobic and impermeable
189 have evolved immune evasion strategies that render the elicitation of effective antibody responses t
190 ns of the cargoes are resolved accurately to render the intracellular transport process in live cells
193 drolysis activity of ATP synthase, which may render the protective role of IF1 in ischemic hearts.
195 the absence of conformational entropy would render the resulting affinity biologically meaningless.
197 via a simple "graft-to" immersion process to render the surface with both nonfouling and protein func
198 upled with their tunable band gap energy can render the vertical 2D MoS2 unique opportunities for env
201 45a DISARM system into Bacillus subtilis has rendered the engineered bacteria protected against phage
207 rapid decline of wild devil populations have rendered the species at risk of inbreeding depression.
209 vivo adaptation in mice and rhesus monkeys, rendering the cagT4SS nonfunctional; however, these mode
210 ectin glycoprotein ligand-1, CD43, and CD44 (rendering the E-selectin ligands cutaneous lymphocyte Ag
213 ucture elements revealed substantial changes rendering the hybrid de facto nonreactive with patients'
214 relies on mitochondrial function for energy, rendering the kidney highly susceptible to ischemic AKI.
215 ibrin formation surrounding the tumor cells, rendering the metastases susceptible to mucosal immunity
217 oteostasis undergoes a decline during aging, rendering the organism susceptible to these pathologies.
218 his population was much lower than expected, rendering the primary endpoint inadequately powered.
221 sleep disruption may be one key factor that renders the aging brain vulnerable to Abeta deposition a
222 amide is cleaved at an enzyme-like rate that renders the amide nonisolable at 35 degrees C and pH 4 o
223 y 0.02; J is the dominant exchange constant) renders the compound an excellent candidate for a spin-(
225 impacts arteries where disturbed blood flow renders the endothelium susceptible to inflammation.
227 though glycosylation improves solubility and renders the metabolites suitable for transport and seque
229 flux and stochasticity during pre-nucleation renders the reactions susceptible to perturbations by ot
230 ctionally, depleting cellular Sal-1 strongly renders the Salmonella bacteria less resistant to the ho
235 of ZIKV to antagonize the mouse IFN response renders the virus highly susceptible to circulating IFN
236 thanides possess similar chemical properties rendering their separation from one another a challenge
237 namic properties of telomeres and telomerase render them difficult to study using ensemble biochemica
238 nd efficacy (treating only those whose genes render them likely to benefit) when implementing psychos
240 of TNFalpha and MEKK4-p38-Noxa pathways that render them susceptible to cystine deprivation-induced n
241 y (WJ) on a molecular level, and potentially render them unsuitable for clinical use in multiple reci
242 ce climatic changes that are large enough to render them unsuitable for coffee farming, in the absenc
244 bumin and nab-paclitaxel in cancer cells and rendered them resistant to nab-paclitaxel-induced apopto
245 ed attenuation of SMPD1 in human NSCLC cells rendered them resistant to serum starvation-induced apop
246 entials of breast cancer stem-like cells and rendered them sensitive to apoptosis induced by chemothe
247 Ecdysone receptor in mid-larval neuroblasts, rendering them competent to respond to the systemic horm
249 ce a dramatic, irreversible efficiency loss, rendering them effectively nonoperational, whereas the S
250 the resulting pancreata were of mouse size, rendering them insufficient for isolating the numbers of
251 grate the growth of all plant parts instead, rendering them less affected by mechanisms such as compe
255 ssion in virus-specific CD8 T cells in mice, rendering them sensitive to anti-4-1BB agonist therapy.
257 efective glycine uptake in DLBCL cell lines, rendering them uniquely dependent upon SHMT enzymatic ac
258 demiology of immunocompromised patients that renders them a particularly high-risk population to inte
259 t the iron dependence of ovarian cancer TICs renders them exquisitely sensitive in vivo to agents tha
260 increased ribosome loading of modified mRNAs renders them more permissive for initiation by favoring
261 d lipid metabolism found in NF2-mutant cells renders them sensitive to elevated levels of malonyl-CoA
263 that expressing hNTCP on macaque hepatocytes renders them susceptible to HBV infection, thereby estab
265 whether disturbances to T cell immunity may render these patients vulnerable to fungal infections.
266 originating from a twin microstructure, has rendered these steels almost useless in martensite state
267 ected yet vital role in stage V gametocytes, rendering these cells exquisitely sensitive to decreases
268 sses pro-inflammatory macrophage activation, rendering these cells inefficient at controlling infecti
269 patterns that are conserved across tissues, rendering these CpGs novel epigenetic biomarkers for hea
270 nts for an accurate spectral reconstruction, rendering these experiments ineffective for high-through
271 ions in the salience of conditioned stimuli, rendering these stimuli less able to be learned about an
272 ression of the polyubiquitin gene UBB, which renders these cancer cells sensitive to further decrease
273 perimental evidences that beta-CDs inclusion renders these compounds more stability towards the oxidi
274 , involving Archimedean and Platonic bodies, renders these supramolecular keplerates as a class of ca
275 brain development and plasticity, they also render this period a particularly sensitive one for envi
277 -ion spectroscopy coupled with tandem MS may render this the key technology to unravel complex glycom
278 the chloramphenicol acetyltransferase gene, rendering this organism insensitive to its toxicity.
279 hotoreaction was cytocompatible and tunable, rendering this platform amenable to studies of dynamic m
280 liminate the actions of pyrrolidinones, thus rendering this series uniquely sensitive to subunit stoi
281 py (SMLM) on cells expressing mCherry, which renders this approach applicable to a very wide range of
284 nical aspects of different technologies that render those methods more or less suitable for different
286 -rapamycin-binding site of Tor2's FRB domain rendering TORC2 rapamycin insensitive and recessing the
287 stic modelling of a specific immune networks renders transcriptome data valuable for the prediction o
290 Mutations in EGFR drive tumor growth but render tumor cells sensitive to treatment with EGFR tyro
291 oenvironmental alteration by CSF-1R blockade renders tumor cells more susceptible to receptor tyrosin
293 ction of cells undergoing active replication rendered tumour cells more resistant to Chk1 inhibitor-i
297 ; the resulting water-soluble cages could be rendered water-insoluble through reverse anion exchange.
298 Systemic neutrophil depletion was found to render wild-type mice highly sensitive to respiratory F.
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