1 Through deep amplicon sequencing,
we uncovered 148 unique alleles at two loci whose relati
2 Here,
we uncover 15 phenotypic and ontogenetic features that d
3 We uncovered 16 signaling pathways (such as fibroblast g
4 sing a whole-genome RNA interference screen,
we uncovered 26 novel regulators of insulin transcriptio
5 In conclusion,
we uncover a cAMP-independent function of Epac1 at the P
6 ng live-tissue and super-resolution imaging,
we uncover a centrosome-nucleated wheel-like microtubule
7 Here
we uncover a complex network comprising a promoter-assoc
8 e-based zebrafish model for CHARGE syndrome,
we uncover a complex spectrum of abnormalities in the ne
9 In addition,
we uncover a defect in protein glycosylation intrappc11m
10 Thus,
we uncover a DNA under replication-53BP1 nuclear body fo
11 Here
we uncover a dual molecular mechanism by which the CHK2-
12 We uncover a dual regulatory role for chromatin during D
13 ng our analysis to model much larger wounds,
we uncover a dynamic behavioral change in the responding
14 Here
we uncover a family of polyketides native to the anaerob
15 Here,
we uncover a full-length endogenous retrovirus envelope
16 We uncover a functional asymmetry within the heart of co
17 Striving to explain this discrepancy,
we uncover a functional mechanism of A-to-I editing in r
18 LRC5 in MHCI transcription in activated DCs,
we uncover a general mechanism counteracting low MHCI su
19 Finally,
we uncover a growth promotion gene expression signature
20 We uncover a H1 enhancer sufficient to drive reporter ge
21 Here
we uncover a hierarchical role of ISL1 in cardiac progen
22 Here
we uncover a link between ESX-5 and the Pst/SenX3-RegX3
23 nhibitory interneurons, and sensory neurons,
we uncover a mechanism for generating alternative startl
24 We uncover a metastasis suppressing role for FAF1 throug
25 hemical genomics screen in Escherichia coli,
we uncover a mode of action for DTPs-the disruption of m
26 Here,
we uncover a modular structure of the human SKI-1/S1P pr
27 Using in vivo and in vitro approaches,
we uncover a molecular pathway whereby direct phosphoryl
28 s, single-cell analyses, and gene knockouts,
we uncover a multi-organ web of tissue-resident memory T
29 Here,
we uncover a mutation (I1042M) in the chitin synthase 1
30 In this article,
we uncover a nanoimmunotherapy using specially designed
31 Additionally,
we uncover a negative feedback loop between actin remode
32 Moreover,
we uncover a neural substrate of such dynamic prioritiza
33 Here,
we uncover a new defining feature of IDS: mothers signif
34 Overall,
we uncover a new feature of BIR and propose that tight c
35 Taken together,
we uncover a new function of minocycline, which stabiliz
36 Here,
we uncover a new mechanism where the transcription facto
37 Here
we uncover a new paradigm for sensing oxidative stress c
38 Here
we uncover a new role for the F-BAR protein pacsin2 in t
39 Here,
we uncover a new role of Pin1 in glutamatergic signaling
40 the mutational history of individual cells,
we uncover a novel mutational signature in healthy aging
41 Here,
we uncover a novel role for a subfamily of MAP4 kinases
42 Finally,
we uncover a novel role for Aurora-B regulated Astrin-SK
43 Here,
we uncover a novel role for Eya and So in promoting cell
44 Here,
we uncover a novel role for the actin-regulatory protein
45 Here
we uncover a novel role for the CNG channel subunit, CNG
46 Here,
we uncover a novel role for the Shu complex in the repai
47 Altogether,
we uncover a novel signaling pathway showing that alpha1
48 t the early stages of rice leaf development,
we uncover a palette of genes whose expression likely un
49 We uncover a poly(A) tail-based regulatory mechanism tha
50 We uncover a previously unappreciated role for Mannose p
51 forward genetics and cytological screening,
we uncover a previously uncharacterized and polarized co
52 Here,
we uncover a previously unidentified molecular mechanism
53 Here,
we uncover a previously unrecognized interplay between t
54 ulk metallic glasses and granular materials,
we uncover a regime of universal deformation dynamics.
55 We uncover a regulatory circuit that responds to low cyt
56 Here,
we uncover a regulatory mechanism by which glucose recru
57 Overall,
we uncover a regulatory mode of the transcriptional acti
58 We uncover a retrograde extension mechanism for axon gro
59 Here,
we uncover a role for AEA and its receptor, cannabinoid
60 We uncover a role in senescence for the potent tumor sup
61 From the studies,
we uncover a sequential, two-step mechanism of cellular
62 Thus,
we uncover a surprising proinflammatory role for PPARgam
63 Here,
we uncover a surprising role of the anterograde molecula
64 Here
we uncover a synthetic genetic interaction between C. el
65 Here,
we uncover a systemic program that leverages the amyloid
66 Here
we uncover a third biogenesis strategy that, similar to
67 Thus, using APL as a model,
we uncover a tolerogenic pathway that may represent a re
68 Using Pif1 as a sensor,
we uncover a transition point in which 34 bp of telomeri
69 In this study,
we uncover a unique role for BIRC3, as an IAP that is cr
70 lular site of lipid accumulation in neurons,
we uncover a vicious cycle of cholesterol synthesis and
71 ermediate quantification and carbon tracing,
we uncover a vitamin B12-independent propionate breakdow
72 Finally,
we uncover a widespread loss of H3K27 acetylation in par
73 A neurons, which are crucial for chemotaxis,
we uncovered a Ca(2+) NFL leading to adaptation that wou
74 Here,
we uncovered a central role for epidermal growth factor
75 aging, optogenetics and behavioral analyses,
we uncovered a circuit specific for mechanonociception b
76 We uncovered a conserved AGO subfamily absent in angiosp
77 ontacts with the 40S entry or exit channels,
we uncovered a critical role for eIF3 requiring the eIF3
78 We uncovered a critical role for the IL-1beta pathway in
79 Moreover,
we uncovered a crucial role of the CXCL10/CXCR3 axis, wi
80 In this study,
we uncovered a distinct and critical role for miR-18a in
81 We uncovered a distinct class of miRNAs that target near
82 By messenger RNA sequencing,
we uncovered a dramatic difference between transcription
83 al, redox-biosensor, and genetic strategies,
we uncovered a functional linkage between specific deter
84 In line with this binding,
we uncovered a functional role for Nup98 in mediating en
85 Surprisingly,
we uncovered a hitherto uncharacterized monosynaptic con
86 We uncovered a large number of TDP-43-dependent splicing
87 We uncovered a marked increase in this YAP1 phosphorylat
88 In this study,
we uncovered a means of vaccinia virus adaptation involv
89 transcription factors control transcription,
we uncovered a molecular mechanism that increases produc
90 We uncovered a multipolar nematic phase of matter in the
91 We uncovered a negative feedback loop in M2 myeloid cell
92 Additionally,
we uncovered a new ompA promoter, which we named P3, uti
93 In this work,
we uncovered a new role for the microtubule-associated p
94 By analyzing a kinetic model,
we uncovered a nonlinear initial dose threshold that is
95 Furthermore,
we uncovered a nonuniform pattern of reactivation of fea
96 Here,
we uncovered a novel and the pivotal role of Arabidopsis
97 In the present study,
we uncovered a novel function of tau in its ability to r
98 Here,
we uncovered a novel mechanism by which catecholamines i
99 Moreover,
we uncovered a novel mechanism by which IL-37 suppressed
100 s neuromuscular junction as a model synapse,
we uncovered a novel mechanism that regulates the distri
101 ING finger 1 (MGRN1) affects cell viability,
we uncovered a novel role for its interactor, the ESCRT-
102 In this study,
we uncovered a novel role for the microglial complement
103 We uncovered a novel site (Y382-384) within the P2X7 rec
104 We uncovered a novel, nontranscriptional function for RB
105 , and functional studies of candidate genes,
we uncovered a possible explanation for this unexpected
106 Here,
we uncovered a previously uncharacterized protein family
107 ing knockdown and loss-of-function analyses,
we uncovered a previously unrecognized role for the tran
108 Moreover,
we uncovered a relationship between AXL and the cellular
109 ociated actinobacteria and pathogenic fungi,
we uncovered a remarkable fungal metabolite, homodimeric
110 In addition,
we uncovered a remarkable negative impact of the TLR4 pa
111 We uncovered a rich diversity of predicted Cas9 proteins
112 Here
we uncovered a role for intestinal hypoxia-inducible fac
113 f-function cell and mouse models of Slc22a1,
we uncovered a role of SLC22A1 in the efflux of acylcarn
114 Here
we uncovered a role of the THO complex in restricting th
115 In summary,
we uncovered a signalling pathway operating specifically
116 In human HCC sections
we uncovered a significant correlation between low frequ
117 We uncovered a single phosphorylation site in the licens
118 In high-grade (grade 3) breast cancers,
we uncovered a striking link between high microenvironme
119 Using DSBCapture,
we uncovered a striking relationship between DSBs and el
120 omparing them to the reference pig assembly,
we uncovered a substantial number of novel SNPs and stru
121 D36-overexpressing transgenic (CD36Tg) mice,
we uncovered a surprising function of CD36 in regulating
122 In the present study,
we uncovered a T cell-intrinsic inflammasome that drives
123 ted placebo response, while in another 6/19,
we uncovered a tendency for duloxetine to diminish it.
124 Here
we uncovered a thalamocortical mechanism in which cortic
125 graphical information system (GIS) analysis,
we uncovered a twofold higher incidence of Beijing strai
126 Here,
we uncovered a weak 5'-deoxyribose phosphate (5'-dRP) ly
127 of naturally occurring genetic perturbation,
we uncover abundant variation in longevity and reproduct
128 In addition,
we uncovered admixtures between Siberians and Eastern Eu
129 We uncover an alternative mechanism for anomalous Hall e
130 ottleneck towards opening specific DNA site,
we uncover an earlier 100- to 500-mus step that we assig
131 Here,
we uncover an epigenetic program mediated by the NAD(+)-
132 Altogether,
we uncover an immune-regulated cellular pathway of defen
133 Consistent with our model,
we uncover an inverse correlation between ribosome densi
134 Here
we uncover an unanticipated link between ADARs (ADAR1 an
135 arginine sensor for the mTORC1 pathway, and
we uncover an unexpectedly central role for SLC38A9 in a
136 We uncover an unpredicted speciation event in the tropic
137 Using a fragment-based screening approach,
we uncovered an allosteric binding site located near the
138 Examining that model further,
we uncovered an altered cellular immune response that pr
139 ing longitudinal records of online activity,
we uncovered an ecology evolving on a daily time scale t
140 We uncovered an endospermal lipid gap, which channels wa
141 In this study,
we uncovered an immune-regulatory pathway that tempers t
142 In addition to variants in promoters,
we uncovered an important role for variants in 3'UTRs, e
143 Furthermore,
we uncovered an integrated mechanism that acts at the tr
144 Applying this model to the sperm methylomes,
we uncovered an overall evolutionary expansion of the hy
145 We uncover and exploit substrate cleavage preferences di
146 Here
we uncover and mechanistically characterize the NLR Nlrp
147 Besides its key role in the lens,
we uncovered another critical role for alphaB-crystallin
148 Additionally,
we uncover APA of approximately 11,000 expressed genes a
149 Here,
we uncovered at the heart of this response a signaling m
150 ty mapping, array CGH, and exome sequencing,
we uncovered bi-allelic loss-of-function CDK10 mutations
151 We uncovered both shared and unique patterns of diversif
152 Notably,
we uncovered cell state plasticity and adhesion dynamics
153 Finally,
we uncovered cell-type- and cell-cycle-stage-specific co
154 In particular,
we uncovered co-dysregulation of genes associated with o
155 We uncover compelling evidence for the cellular compartm
156 e of Nipbl deficiency in different lineages,
we uncover complex interactions between the cardiac meso
157 We uncover complex T4 inputs and reveal that putative ex
158 Using this approach,
we uncovered complex overlapping expression patterns for
159 e genomes of cucumber, melon and watermelon,
we uncovered conserved syntenic loci encoding metabolic
160 Through functional studies,
we uncover cryptic sequence features within the p27 IDR
161 In this conjuncture,
we uncovered daily oscillations in mitochondrial respira
162 We uncovered differences in inhibitory receptor expressi
163 peripheral sensory structure modifications,
we uncovered differences in relative investment in both
164 Hence, for the first time,
we uncover direct interactions between plastic nanoparti
165 essibility measurements in the Kondo regime,
we uncover directly the charge dynamics of this peculiar
166 Using stage-specific Cre alleles,
we uncovered distinct roles of Notch1 in mononucleated m
167 Remarkably,
we uncovered diurnal oscillations in lipid accumulation
168 Using teeth from captive macaques,
we uncovered elemental imprints specific to disruptions
169 We uncover epigenomic signatures of domestication traits
170 me remodeling complex, which deposits H2A.Z,
we uncovered evidence for functional interactions with c
171 Here,
we uncover,
experimentally, a mode of collective bacteri
172 ly, by CRISPR/Cas9-mediated genomic editing,
we uncover functional hierarchy of constituent enhancers
173 We uncovered gene networks with overlapping feedback loo
174 Thus,
we uncovered genes that modify the interpretation of mor
175 Furthermore,
we uncovered genetic variants in different key regulator
176 he distribution of reported emotional states
we uncover gradients of emotion-from anxiety to fear to
177 We uncover here the function of a gene that supports thi
178 In this context
we uncover here the role of a miRNA, miR-579-3p.
179 In conclusion,
we uncovered here an active cornea-TG axis, driven by PE
180 rating omics analyses in 50 matched samples,
we uncover in Taiwanese patients a predominant mutation
181 placebo analgesia from duloxetine response,
we uncovered in 6/19 participants a tendency of duloxeti
182 Thus
we uncover,
in an adult vertebrate, a novel organization
183 the genomic features driving this accuracy,
we uncover interactions between structural proteins, tra
184 Here
we uncover,
investigate, and discuss previously unaddres
185 Furthermore,
we uncover ionic and cellular mechanisms that suggest un
186 generating high quality EWS-RNA interactome,
we uncovered its specific and prevalent interaction with
187 We uncover Lgl1-dependent tissue-wide community effects
188 To conclude,
we uncovered loss of chromosome 22 in almost half of all
189 We uncover many novel prognostic regulators that were ob
190 and the cell force regulation principle that
we uncover may contribute to the rapid mechanical tissue
191 itor-sensitive or inhibitor-resistant cells,
we uncover Midasin's role in assembling Nsa1 particles,
192 For the first time,
we uncovered modular topology in CAE patients that was s
193 We uncover molecular, cellular, and circuit-level mechan
194 We uncovered multiple genes known to be involved in p53
195 clearly resolving phylogenic relationships,
we uncovered mutated LCP1 and WNK1 as novel CLL drivers,
196 Furthermore,
we uncover neural computations underlying learning about
197 Here,
we uncover new cellular factors and mechanisms involved
198 In addition,
we uncover new targets of investigation in both sexes, w
199 We uncovered new driver mutations in the replication-rep
200 Mechanistically,
we uncover novel direct interactions between endogenous
201 Using the chick embryo,
we uncover novel genes in the gene regulatory network un
202 ineage-guided principal components analysis,
we uncover novel relatedness of particular developmental
203 lyzing cell line responses to 265 compounds,
we uncovered numerous TFs whose activity interacts with
204 specifically in the gonads of both genders,
we uncovered pairing-induced processes within the gonads
205 We uncovered patterns of evolution that were distinct fr
206 aboratory experiments and computer modelling
we uncovered patterns of the foraging behaviour that mig
207 We uncover physical underpinnings of formation of colloi
208 Here,
we uncover posttranslational regulatory mechanisms in th
209 argeted fluorescent proteins and biosensors,
we uncover previously unrecognized cell-type differences
210 We uncovered previously unknown interactions that were n
211 We uncovered previously unreported phenotypic heterogene
212 Finally,
we uncover reQTL effects in multiple GWAS loci and show
213 Moreover, the chemical complexity
we uncovered resulted in the development of an improved
214 We uncovered rhythmic behavior in this mutant by simply
215 Here,
we uncover roles for the Bacillus subtilis PhoP regulon
216 Also,
we uncovered several clinically-relevant interactions in
217 ouse models with extensive human validation,
we uncovered several key regulators of metastatic abilit
218 l neurons in mouse hippocampus and striatum,
we uncovered several principles governing neuronal DNA m
219 We uncovered signaling mediated by Janus kinases (Jaks)
220 While
we uncovered signals unique to racial/ethnic populations
221 prototypical 2D system, a GaAs quantum well,
we uncover signatures of many-body effects involving ele
222 owledge of yeast transcriptional regulation,
we uncovered significant regulatory variation in individ
223 We uncovered specific dsx(+) neurons critical for drivin
224 We uncovered specific interactions between unphosphoryla
225 nologies brought the thrills of discovery as
we uncovered specific proteinase genes and defined speci
226 Consequently,
we uncover statistical results in origami, finding the e
227 nteraction assays and multiple mouse models,
we uncover strain-specific effector/immunity repertoires
228 We uncovered striking regulation of PAR complex composit
229 Also,
we uncovered substantial deficiency in beta-cells that o
230 We uncovered surprising features of nucleosome organizat
231 We uncovered sustained basal autophagy in the gut of Crh
232 Using live-cell imaging,
we uncover that autophagy promotes optimal migratory rat
233 Here,
we uncover that collective resistance can also develop v
234 By using different Dif1 mutant proteins,
we uncover that Dun1 phosphorylates Dif1 Ser-104 and Thr
235 However, here
we uncover that E. coli strains expressing a TruB varian
236 Here,
we uncover that mitochondrial dynamics regulates stem ce
237 Collectively,
we uncover that nickel exposure results in DNMT3b induct
238 We uncover that one of them, nam1, regulates entry into
239 Here,
we uncover that RNF168 links the HR machinery to H2A ubi
240 By screening human cDNA library,
we uncover that the Golgi resident protein acyl-coenzyme
241 We uncover that the least active users are predominantly
242 In Vibrio cholerae,
we uncover that this requirement is due to cytoplasmic s
243 In the present study,
we uncovered that IF1 is upregulated in mouse hearts wit
244 For example,
we uncovered that individuals with reciprocal rearrangem
245 system and subcellular nanobody expression,
we uncovered that maintenance of Mira asymmetric localiz
246 riants in human cancer cells and Drosophila,
we uncovered that MOB1/Warts binding is essential for tu
247 Here
we uncovered that murine endocrine pancreatic progenitor
248 Aided by these tools,
we uncovered that perturbations in the actin cytoskeleto
249 cytic choriomeningitis virus (LCMV) strains,
we uncovered that T cell differentiation and acquisition
250 sing fission yeast cell cycle as an example,
we uncovered that the non-equilibrium network dynamics a
251 Additionally,
we uncovered that this synergism is mediated through Gi,
252 Furthermore,
we uncovered that XRN2 functions as pro-metastatic gene,
253 Altogether,
we uncover the axonal function of the splicing factor SF
254 Here,
we uncover the breakdown of Ohm's law owing to a topolog
255 We uncover the complex multistage process of capsid asse
256 protein-interaction, and functional studies,
we uncover the early events of C. elegans brain assembly
257 Using this framework,
we uncover the existence of a narrow range of parameter
258 ety of energy landscape analysis tools, here
we uncover the features in the molecular architecture of
259 We uncover the formation of spatial patterns of trapped
260 ll-controlled donor/acceptor bilayer system,
we uncover the genuine effects of molecular orientation
261 Here
we uncover the hidden part of the blood proteome via nov
262 Here,
we uncover the mechanisms underlying this paracrine tumo
263 haracterizing myo2 smy1 conditional mutants,
we uncover the molecular function of Smy1 as a factor th
264 Here,
we uncover the molecular mechanism of primed conversion
265 numerical methods in exhaustive simulations,
we uncover the ordering in the underdoped ground state.
266 riori knowledge of interaction partners, and
we uncover the origin of this success.
267 ing predictions from network control theory,
we uncover the relationship between regional controllabi
268 mental data alone however, and in particular
we uncover the role of non-native electrostatic interact
269 Here
we uncover the role of Sip1 in retinogenesis.
270 Here,
we uncover the selective roles of individual members of
271 By studying two concrete systems,
we uncover the statistical correlation between the intri
272 Here,
we uncover the structural basis for both chain selection
273 Using whole-genome sequencing
we uncover the underlying genes for 44 of these mutant p
274 In addition,
we uncovered the distribution of Gag correlated residues
275 tion with CRISPR/Cas9 knockin of GFP fusion,
we uncovered the global targets of UNC-30 and UNC-55.
276 We uncovered the methylation states for nearly identical
277 In addition,
we uncovered the minimum substrate requirements and demo
278 Here,
we uncovered the molecular mechanism by which this phosp
279 Moreover,
we uncovered the network interdigitations of Tau and amy
280 We uncovered the potential causes of its shy-flowering n
281 We uncovered the reason for this phenotype by showing th
282 Specifically,
we uncovered the role of hppH [=1,3,4,6,7,8-hexahydro-2H
283 Here,
we uncovered the role of TOR during the bean (Phaseolus
284 We uncovered the underlying pathway: both treatments act
285 Here,
we uncovered this mechanism via complete theoretical cal
286 In this study
we uncovered,
through targeted ablation, a potential rol
287 Here
we uncover timely new functions of the SASP in promoting
288 cs subject to continuous homodyne detection,
we uncover transient chaos associated with quantum traje
289 Specifically,
we uncovered tsRNA signatures in chronic lymphocytic leu
290 Here,
we uncover two discrete roles and functions of DRFs duri
291 We uncover two distinct modes of signalling inhibition:
292 Here, using Drosophila,
we uncover two distinct reduplicated chromosome response
293 We uncover two distinct regimes of the dynamical phase c
294 We uncover two inter-organ mechanisms of protective immu
295 Through genetic screening in C. elegans,
we uncover two metformin response elements: the nuclear
296 In particular,
we uncover two new states: one contains only the azimuth
297 We uncovered upstream sequences that include start codon
298 Here
we uncover,
using in silico simulation, two feed-forward
299 We uncover various new activities in regulating gene exp
300 Finally, most of the variants that
we uncover within A. fumigatus have been previously hypo